{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neuroinflammatory+Response", "query": { "condition": "Neuroinflammatory Response" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 38, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neuroinflammatory+Response&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-10T13:58:02.602Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00459316", "title": "Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and Youth", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "HIV Infections", "Meningitis" ], "interventions": [ { "name": "Quadrivalent meningococcal conjugate vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "24 Years", "sex": "ALL", "summary": "2 Years to 24 Years" }, "enrollment_count": 384, "start_date": "2007-06", "completion_date": "2013-03", "has_results": true, "last_update_posted_date": "2021-11-03", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 35, "location_summary": "Alhambra, California • Long Beach, California • Los Angeles, California + 25 more", "locations": [ { "city": "Alhambra", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00459316" }, { "nct_id": "NCT04480333", "title": "Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Covid19", "Corona Virus Infection", "Severe Acute Respiratory Syndrome", "Severe Acute Respiratory Infection", "Severe Acute Respiratory Syndrome (SARS) Pneumonia", "Severe Acute Respiratory Syndrome of Upper Respiratory Tract", "Neurodegeneration", "Neuroinflammatory Response" ], "interventions": [ { "name": "Drug: NA-831 - 0.10 mg/kg", "type": "DRUG" }, { "name": "Placebo- 0.10 mg/kg", "type": "DRUG" }, { "name": "Drug: NA-831 - 0.20 mg/kg", "type": "DRUG" }, { "name": "Placebo- 0.20 mg/kg", "type": "DRUG" }, { "name": "Drug: GS-5734 - 1.00 mg/kg", "type": "DRUG" }, { "name": "Placebo- 1.00 mg/kg", "type": "DRUG" }, { "name": "Drug: GS-5734 - 2.00 mg/kg", "type": "DRUG" }, { "name": "Placebo- 2.00 mg/kg", "type": "DRUG" }, { "name": "Drugs: NA-831 (0.10 mg/kg) plus GS-5734 (1.00 mg/kg)", "type": "COMBINATION_PRODUCT" }, { "name": "Placebo 0.10 mg + 1.00 mg/kg", "type": "COMBINATION_PRODUCT" }, { "name": "Drugs: NA-831 (0.20 mg/kg) plus GS-5734 (2.00 mg/kg)", "type": "COMBINATION_PRODUCT" }, { "name": "Placebo 0.20 mg + 2.00 mg/kg", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "DRUG", "COMBINATION_PRODUCT" ], "sponsor": "Biomed Industries, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "21 Years to 50 Years" }, "enrollment_count": 45, "start_date": "2020-09-15", "completion_date": "2021-03-31", "has_results": false, "last_update_posted_date": "2020-07-21", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 1, "location_summary": "Sunnyvale, California", "locations": [ { "city": "Sunnyvale", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04480333" }, { "nct_id": "NCT00777790", "title": "Study of a Booster Dose of Meningococcal Diphtheria Toxoid Conjugate Vaccine in Adolescents", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Meningitis", "Meningococcemia" ], "interventions": [ { "name": "Meningococcal Polysaccharide Diphtheria Toxoid Conjugate", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "13 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "13 Years to 21 Years" }, "enrollment_count": 241, "start_date": "2004-02", "completion_date": "2005-04", "has_results": true, "last_update_posted_date": "2014-02-14", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 9, "location_summary": "Atlanta, Georgia • Marietta, Georgia • Woburn, Massachusetts + 6 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Marietta", "state": "Georgia" }, { "city": "Woburn", "state": "Massachusetts" }, { "city": "Albany", "state": "New York" }, { "city": "Akron", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00777790" }, { "nct_id": "NCT00474526", "title": "A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Vaccine In Infants", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Meningitis, Meningococcal" ], "interventions": [ { "name": "Meningococcal ACWY Conjugate Vaccine", "type": "BIOLOGICAL" }, { "name": "DTaP-IPV-HBV", "type": "BIOLOGICAL" }, { "name": "Hib", "type": "BIOLOGICAL" }, { "name": "Rotavirus", "type": "BIOLOGICAL" }, { "name": "Pneumococcal 7-valent Conjugate Vaccine", "type": "BIOLOGICAL" }, { "name": "HAV", "type": "BIOLOGICAL" }, { "name": "MMR-V", "type": "BIOLOGICAL" }, { "name": "DTaP", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Novartis Vaccines", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "2 Months", "maximum_age": "2 Months", "sex": "ALL", "summary": "2 Months to 2 Months" }, "enrollment_count": 4545, "start_date": "2007-03", "completion_date": "2009-11", "has_results": true, "last_update_posted_date": "2014-03-24", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 53, "location_summary": "Bessemer, Alabama • Birmingham, Alabama • Downey, California + 43 more", "locations": [ { "city": "Bessemer", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Downey", "state": "California" }, { "city": "Oakland", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00474526" }, { "nct_id": "NCT01203345", "title": "Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Infant, Newborn", "Infant, Low Birth Weight", "Infant, Small for Gestational Age", "Infant, Premature", "Sepsis" ], "interventions": [ { "name": "IVIG", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NICHD Neonatal Research Network", "sponsor_class": "NETWORK", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": "72 Hours", "sex": "ALL", "summary": "Up to 72 Hours" }, "enrollment_count": 2416, "start_date": "1988-01", "completion_date": "1991-03", "has_results": false, "last_update_posted_date": "2019-03-22", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 8, "location_summary": "Birmingham, Alabama • Washington D.C., District of Columbia • Miami, Florida + 5 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Miami", "state": "Florida" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01203345" }, { "nct_id": "NCT04263454", "title": "The Innate Central Nervous System Immune Response to an Experimental Immune Challenge in People With Fibromyalgia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Fibromyalgia" ], "interventions": [ { "name": "Endotoxin, Escherichia Coli", "type": "DRUG" }, { "name": "Magnetic Resonance Spectroscopy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "University of Alabama at Birmingham", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "FEMALE", "summary": "18 Years to 55 Years · Female only" }, "enrollment_count": 36, "start_date": "2020-03-11", "completion_date": "2021-12-22", "has_results": true, "last_update_posted_date": "2023-04-14", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 1, "location_summary": "Birmingham, Alabama", "locations": [ { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT04263454" }, { "nct_id": "NCT04542161", "title": "Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Fatigue Syndrome", "Myalgic Encephalomyelitis" ], "interventions": [ { "name": "NAC 900mg/day", "type": "DRUG" }, { "name": "NAC 3600mg/day", "type": "DRUG" }, { "name": "NAC 0mg/day (Placebo)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Weill Medical College of Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "21 Years to 60 Years" }, "enrollment_count": 95, "start_date": "2020-09-01", "completion_date": "2026-04-30", "has_results": false, "last_update_posted_date": "2026-02-25", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04542161" }, { "nct_id": "NCT00442169", "title": "Safety and Immunogenicity of ChimeriVax-WN02 West Nile Vaccine in Healthy Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "West Nile Fever" ], "interventions": [ { "name": "ChimeriVax-WN02 Low Dose", "type": "BIOLOGICAL" }, { "name": "ChimeriVax-WN02 Medium Dose", "type": "BIOLOGICAL" }, { "name": "ChimeriVax-WN02 High Dose", "type": "BIOLOGICAL" }, { "name": "0.9% Saline solution", "type": "BIOLOGICAL" }, { "name": "0.9 % NaCl solution", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 208, "start_date": "2005-12", "completion_date": "2009-04", "has_results": true, "last_update_posted_date": "2016-04-14", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 5, "location_summary": "Phoenix, Arizona • Idaho Falls, Idaho • Lenexa, Kansas + 2 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Idaho Falls", "state": "Idaho" }, { "city": "Lenexa", "state": "Kansas" }, { "city": "Springfield", "state": "Missouri" }, { "city": "Norfolk", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00442169" }, { "nct_id": "NCT03674541", "title": "The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome", "Chronic Fatigue Syndrome", "Myalgic Encephalomyelitis", "Exercise Intolerance", "Dysautonomia", "Low Ventricular Filling Pressures (Preload Failure)", "Postural Orthostatic Tachycardia Syndrome", "Orthostatic Hypotension", "Fibromyalgia" ], "interventions": [ { "name": "Pyridostigmine Bromide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 45, "start_date": "2020-01-14", "completion_date": "2021-12-20", "has_results": true, "last_update_posted_date": "2022-11-08", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03674541" }, { "nct_id": "NCT02092883", "title": "Evaluation of Neuroinflammation in Children With Infantile Spasms", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Infantile Spasms" ], "interventions": [ { "name": "ACTH", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Wayne State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 8, "start_date": "2013-03", "completion_date": "2017-07", "has_results": false, "last_update_posted_date": "2017-11-07", "last_synced_at": "2026-06-10T13:58:02.602Z", "location_count": 1, "location_summary": "Detroit, Michigan", "locations": [ { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT02092883" } ] }