{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neuronal+Ceroid+Lipofuscinosis+CLN3&page=2",
    "query": {
      "condition": "Neuronal Ceroid Lipofuscinosis CLN3",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neuronal+Ceroid+Lipofuscinosis+CLN3&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T01:20:56.682Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04974307",
      "title": "Optic-to-Audio Device in a Pediatric Cohort With CLN3-related Conditions or Low Vision",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "CLN3-related Disorders",
        "Non-CLN3 Related Low Vision"
      ],
      "interventions": [
        {
          "name": "OrCam MyEye 2",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Years to 18 Years"
      },
      "enrollment_count": 11,
      "start_date": "2021-09-30",
      "completion_date": "2023-10-07",
      "has_results": true,
      "last_update_posted_date": "2024-10-23",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04974307"
    },
    {
      "nct_id": "NCT01966757",
      "title": "Neuronal Ceroid Lipofuscinosis and Associated Sleep Abnormalities",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neuronal Ceroid Lipofuscinosis",
        "Batten's Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 57,
      "start_date": "2013-07",
      "completion_date": "2016-07",
      "has_results": false,
      "last_update_posted_date": "2016-07-26",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01966757"
    },
    {
      "nct_id": "NCT02725580",
      "title": "Gene Therapy For Children With Variant Late Infantile Neuronal Ceroid Lipofuscinosis 6 (vLINCL6) Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Variant Late-Infantile Neuronal Ceroid Lipofuscinosis"
      ],
      "interventions": [
        {
          "name": "AT-GTX-501",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "Emily de los Reyes",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Year and older"
      },
      "enrollment_count": 13,
      "start_date": "2016-05",
      "completion_date": "2024-10",
      "has_results": true,
      "last_update_posted_date": "2025-10-24",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02725580"
    },
    {
      "nct_id": "NCT02678689",
      "title": "A Safety, Tolerability, and Efficacy Study of BMN 190 in Pediatric Patients < 18 Years of Age With CLN2 Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Jansky-Bielschowsky Disease",
        "Batten Disease",
        "Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2",
        "CLN2 Disease",
        "CLN2 Disorder"
      ],
      "interventions": [
        {
          "name": "BMN 190 recombinant human tripeptidyl peptidase-1 (rhTPP1)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Intracerebroventricular access device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE"
      ],
      "sponsor": "BioMarin Pharmaceutical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 14,
      "start_date": "2016-01-22",
      "completion_date": "2022-04-20",
      "has_results": true,
      "last_update_posted_date": "2025-02-17",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02678689"
    },
    {
      "nct_id": "NCT05642221",
      "title": "Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Juvenile Neuronal Ceroid Lipofuscinosis",
        "Smith-Lemli-Opitz Syndrome",
        "Creatine Transporter Deficiency",
        "Niemann-Pick Disease Type C1"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "6 Months to 110 Years"
      },
      "enrollment_count": 73,
      "start_date": "2023-01-23",
      "completion_date": "2025-04-25",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05642221"
    },
    {
      "nct_id": "NCT04644549",
      "title": "Natural History Study of Batten Disease",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Batten Disease",
        "Neuronal Ceroid Lipofuscinosis CLN6",
        "Neuronal Ceroid Lipofuscinosis CLN3"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Emily de los Reyes",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 10,
      "start_date": "2021-04-27",
      "completion_date": "2022-03-11",
      "has_results": false,
      "last_update_posted_date": "2025-07-30",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04644549"
    },
    {
      "nct_id": "NCT04273243",
      "title": "Long-Term Follow Up of CLN6 Batten Disease Subjects Following Gene Transfer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "CLN6",
        "Batten Disease"
      ],
      "interventions": [
        {
          "name": "AT-GTX-501",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "Emily de los Reyes",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Months and older"
      },
      "enrollment_count": 10,
      "start_date": "2020-01-24",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-02",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04273243"
    },
    {
      "nct_id": "NCT03307304",
      "title": "Investigations of Juvenile Neuronal Ceroid Lipofuscinosis",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)",
        "Batten Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Week",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "1 Week to 100 Years"
      },
      "enrollment_count": 300,
      "start_date": "2017-11-27",
      "completion_date": "2050-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03307304"
    },
    {
      "nct_id": "NCT05174039",
      "title": "An Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of Subjects With Batten Ceroid Lipofuscinosis, Neuronal 3 (CLN3) Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Batten Disease"
      ],
      "interventions": [
        {
          "name": "Miglustat 100 milligrams (mg) Oral Capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Beyond Batten Disease Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2022-03-10",
      "completion_date": "2024-05-30",
      "has_results": true,
      "last_update_posted_date": "2025-09-09",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05174039"
    },
    {
      "nct_id": "NCT01414985",
      "title": "AAVRh.10 Administered to Children With Late Infantile Neuronal Ceroid Lipofuscinosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Late Infantile Neuronal Ceroid Lipofuscinosis",
        "Batten Disease"
      ],
      "interventions": [
        {
          "name": "AAVrh.10CUCLN2",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Years to 18 Years"
      },
      "enrollment_count": 8,
      "start_date": "2010-04-15",
      "completion_date": "2017-02-08",
      "has_results": false,
      "last_update_posted_date": "2020-08-31",
      "last_synced_at": "2026-07-24T01:20:56.682Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01414985"
    }
  ]
}