{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neuropathic+Leg+Pain",
    "query": {
      "condition": "Neuropathic Leg Pain"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T21:20:16.643Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01512121",
      "title": "Spinal Cord Stimulation and Functional MRI",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Complex Regional Pain Syndrome (CRPS)",
        "Neuropathic Leg Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Vibhor Krishna",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 10,
      "start_date": "2011-09",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2019-09-23",
      "last_synced_at": "2026-06-26T21:20:16.643Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01512121"
    },
    {
      "nct_id": "NCT04687215",
      "title": "Diabetic Neuropathy in Spinal Cord Stimulator Patients",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetes Mellitus",
        "Neuropathy",
        "Neuropathic Pain",
        "Vascular Diseases",
        "Vascular Stiffness",
        "Microvascular Changes",
        "Pain, Chronic"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2022-01-27",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-05",
      "last_synced_at": "2026-06-26T21:20:16.643Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04687215"
    },
    {
      "nct_id": "NCT00399841",
      "title": "Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intractable Neuropathic Pain",
        "Pain",
        "Back Pain",
        "Lower Extremity Pain"
      ],
      "interventions": [
        {
          "name": "Precision for Spinal Cord Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2006-11",
      "completion_date": "2008-11",
      "has_results": true,
      "last_update_posted_date": "2020-12-19",
      "last_synced_at": "2026-06-26T21:20:16.643Z",
      "location_count": 1,
      "location_summary": "Belleville, Illinois",
      "locations": [
        {
          "city": "Belleville",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00399841"
    },
    {
      "nct_id": "NCT01976598",
      "title": "Sub-Sensory Intraspinal Neurostimulation Therapy",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Back Pain",
        "Back Pain With Radiation",
        "Pain in Leg, Unspecified"
      ],
      "interventions": [
        {
          "name": "Sub-Sensory Stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Algos Clinical Development Thomas L. Yearwood, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "22 Years to 85 Years"
      },
      "enrollment_count": 1,
      "start_date": "2013-10",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2015-01-19",
      "last_synced_at": "2026-06-26T21:20:16.643Z",
      "location_count": 1,
      "location_summary": "Pascagoula, Mississippi",
      "locations": [
        {
          "city": "Pascagoula",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01976598"
    },
    {
      "nct_id": "NCT07260656",
      "title": "Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Diabetic Neuropathies, Painful",
        "Diabetic Foot",
        "Diabetic Peripheral Neuropathy"
      ],
      "interventions": [
        {
          "name": "Capsaicin Palmitate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Carilion Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "25 Years to 75 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-11-26",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-06-26T21:20:16.643Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07260656"
    },
    {
      "nct_id": "NCT00375960",
      "title": "A Research Study of V3381 for the Treatment of Diabetic Peripheral Neuropathic Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pain",
        "Diabetic Neuropathies"
      ],
      "interventions": [
        {
          "name": "V3381",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vernalis (R&D) Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 50,
      "start_date": "2006-06",
      "completion_date": "2007-04",
      "has_results": false,
      "last_update_posted_date": "2007-04-02",
      "last_synced_at": "2026-06-26T21:20:16.643Z",
      "location_count": 5,
      "location_summary": "Walnut Creek, California • Clearwater, Florida • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Walnut Creek",
          "state": "California"
        },
        {
          "city": "Clearwater",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Southfield",
          "state": "Michigan"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00375960"
    },
    {
      "nct_id": "NCT03539081",
      "title": "Spinal Cord Stimulation for Restless Legs Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Restless Legs Syndrome",
        "Neuropathic Pain"
      ],
      "interventions": [
        {
          "name": "Dual-energy X-ray absorptiometry Scan",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Laboratory Measurements",
          "type": "OTHER"
        },
        {
          "name": "Blood Flow Measurement",
          "type": "OTHER"
        },
        {
          "name": "Continuous Blood Pressure",
          "type": "OTHER"
        },
        {
          "name": "Partial pressure of oxygen",
          "type": "OTHER"
        },
        {
          "name": "Microneurography",
          "type": "OTHER"
        },
        {
          "name": "Anthropometric Measurements",
          "type": "OTHER"
        },
        {
          "name": "John Hopkins Restless Legs Severity Scale",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Continuous Blood Pressure Diary",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Marshall Holland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 15,
      "start_date": "2016-07-05",
      "completion_date": "2020-04-23",
      "has_results": true,
      "last_update_posted_date": "2023-09-21",
      "last_synced_at": "2026-06-26T21:20:16.643Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03539081"
    },
    {
      "nct_id": "NCT06741579",
      "title": "Mechanisms of Stimulation for Pain Alleviation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Neuropathic Pain in the Low Back and Legs",
        "Peripheral Nerve Stimulation",
        "Chronic Neuropathic Pain"
      ],
      "interventions": [
        {
          "name": "Peripheral Nerve Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Care Regimen",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 148,
      "start_date": "2025-09-26",
      "completion_date": "2028-11-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-02",
      "last_synced_at": "2026-06-26T21:20:16.643Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06741579"
    }
  ]
}