{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neurotoxicity", "query": { "condition": "Neurotoxicity" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 124, "total_pages": 13, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Neurotoxicity&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-07T15:20:32.216Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00068445", "title": "Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Neurotoxicity", "Pain", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "lamotrigine", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 131, "start_date": "2004-02", "completion_date": "2013-11", "has_results": true, "last_update_posted_date": "2018-05-04", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 23, "location_summary": "Scottsdale, Arizona • Jacksonville, Florida • Atlanta, Georgia + 20 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Honolulu", "state": "Hawaii" }, { "city": "Peoria", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00068445" }, { "nct_id": "NCT00363129", "title": "Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Neurotoxicity", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "vitamin E", "type": "DIETARY_SUPPLEMENT" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 207, "start_date": "2006-12", "completion_date": "2014-08", "has_results": true, "last_update_posted_date": "2016-07-06", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 69, "location_summary": "Bloomington, Illinois • Canton, Illinois • Carthage, Illinois + 46 more", "locations": [ { "city": "Bloomington", "state": "Illinois" }, { "city": "Canton", "state": "Illinois" }, { "city": "Carthage", "state": "Illinois" }, { "city": "Eureka", "state": "Illinois" }, { "city": "Galesburg", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00363129" }, { "nct_id": "NCT02890030", "title": "The Platinum Study Comparison Group", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Testicular Neoplasms" ], "interventions": [ { "name": "Questionnaire", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Lawrence Einhorn", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "MALE", "summary": "18 Years to 55 Years · Male only" }, "enrollment_count": 102, "start_date": "2015-05", "completion_date": "2017-06-14", "has_results": false, "last_update_posted_date": "2020-04-08", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 1, "location_summary": "Indianapolis, Indiana", "locations": [ { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02890030" }, { "nct_id": "NCT00437060", "title": "Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Childhood B Acute Lymphoblastic Leukemia", "Childhood T Acute Lymphoblastic Leukemia", "Cognitive Side Effects of Cancer Therapy", "Long-Term Effects Secondary to Cancer Therapy in Children", "Neurotoxicity Syndrome", "Psychological Impact of Cancer", "Untreated Childhood Acute Lymphoblastic Leukemia" ], "interventions": [ { "name": "Cognitive Assessment", "type": "PROCEDURE" }, { "name": "Diffusion Tensor Imaging", "type": "PROCEDURE" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Pharmacological Study", "type": "OTHER" }, { "name": "Psychosocial Assessment and Care", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "Children's Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "17 Years", "sex": "ALL", "summary": "1 Year to 17 Years" }, "enrollment_count": 233, "start_date": "2007-01", "completion_date": null, "has_results": false, "last_update_posted_date": "2017-07-21", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 102, "location_summary": "Birmingham, Alabama • Downey, California • Long Beach, California + 83 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Downey", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00437060" }, { "nct_id": "NCT01099449", "title": "Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapeutic Agent Toxicity", "Colorectal Cancer", "Neuropathy", "Neurotoxicity" ], "interventions": [ { "name": "calcium gluconate", "type": "DRUG" }, { "name": "magnesium sulfate", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" }, { "name": "oxaliplatin", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 362, "start_date": "2010-06", "completion_date": "2013-03", "has_results": true, "last_update_posted_date": "2022-11-03", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 404, "location_summary": "Fairbanks, Alaska • Antioch, California • Fairfield, California + 278 more", "locations": [ { "city": "Fairbanks", "state": "Alaska" }, { "city": "Antioch", "state": "California" }, { "city": "Fairfield", "state": "California" }, { "city": "Fremont", "state": "California" }, { "city": "Fresno", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01099449" }, { "nct_id": "NCT01789047", "title": "Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Idiopathic Parkinson's Disease", "Drug Induced Dyskinesia" ], "interventions": [ { "name": "Topiramate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Amantadine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Rush University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "30 Years to 90 Years" }, "enrollment_count": 42, "start_date": "2013-03", "completion_date": "2016-07", "has_results": true, "last_update_posted_date": "2019-04-16", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 5, "location_summary": "Birmingham, Alabama • Tampa, Florida • Chicago, Illinois + 2 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tampa", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT01789047" }, { "nct_id": "NCT00003624", "title": "Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cervical Cancer", "Endometrial Cancer", "Fallopian Tube Cancer", "Neurotoxicity", "Ovarian Cancer", "Primary Peritoneal Cavity Cancer", "Sarcoma" ], "interventions": [ { "name": "amifostine trihydrate", "type": "DRUG" }, { "name": "cisplatin", "type": "DRUG" }, { "name": "paclitaxel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Gynecologic Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "FEMALE", "summary": "Female only" }, "enrollment_count": null, "start_date": "1998-12", "completion_date": null, "has_results": false, "last_update_posted_date": "2013-04-11", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 8, "location_summary": "Orange, California • Washington D.C., District of Columbia • Atlanta, Georgia + 5 more", "locations": [ { "city": "Orange", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT00003624" }, { "nct_id": "NCT00263861", "title": "Nerve Function in Older Diabetic Patients Who Are Undergoing Chemotherapy for Metastatic Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Neurotoxicity", "Unspecified Adult Solid Tumor, Protocol Specific" ], "interventions": [ { "name": "management of therapy complications", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Case Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 14, "start_date": "2005-03", "completion_date": "2007-09", "has_results": false, "last_update_posted_date": "2010-06-11", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00263861" }, { "nct_id": "NCT01362205", "title": "Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Alcohol Withdrawal Delirium", "Alcohol Withdrawal Associated Autonomic Hyperactivity", "Alcohol Withdrawal Hallucinosis", "Alcohol Withdrawal-Induced Delirium Tremens" ], "interventions": [ { "name": "Dexmedetomidine", "type": "DRUG" }, { "name": "Placebos", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Denver Health and Hospital Authority", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "89 Years", "sex": "ALL", "summary": "18 Years to 89 Years" }, "enrollment_count": 49, "start_date": "2012-03", "completion_date": "2016-09", "has_results": true, "last_update_posted_date": "2017-11-06", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 7, "location_summary": "Colorado Springs, Colorado • Denver, Colorado • Lakewood, Colorado + 2 more", "locations": [ { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Denver", "state": "Colorado" }, { "city": "Denver", "state": "Colorado" }, { "city": "Lakewood", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01362205" }, { "nct_id": "NCT03561168", "title": "Review of Diagnostic Yield of MRI Brain Results in Children Under Age 3 Years", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Seizures", "Development Delay", "Anesthetic Neurotoxicity" ], "interventions": [ { "name": "Change in plan of care based on MRI results", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "1095 Days", "sex": "ALL", "summary": "Up to 1095 Days" }, "enrollment_count": 561, "start_date": "2017-10-12", "completion_date": "2018-06-15", "has_results": false, "last_update_posted_date": "2018-06-19", "last_synced_at": "2026-06-07T15:20:32.216Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03561168" } ] }