{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nicotine",
    "query": {
      "condition": "Nicotine"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 1142,
    "total_pages": 115,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nicotine&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T03:35:29.707Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03830892",
      "title": "Effects of E-Cigarette Power and Nicotine Content in Dual Users and Vapers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarettes"
      ],
      "interventions": [
        {
          "name": "E-cigarette Lab Session 15 watts, 10 mg nicotine",
          "type": "OTHER"
        },
        {
          "name": "E-cigarette Lab Session 15 watts, 30 mg nicotine",
          "type": "OTHER"
        },
        {
          "name": "E-cigarette Lab Session 30 watts, 10 mg nicotine",
          "type": "OTHER"
        },
        {
          "name": "E-cigarette Lab Session 30 watts, 30 mg nicotine",
          "type": "OTHER"
        },
        {
          "name": "Own Brand Session - E-cigarette",
          "type": "OTHER"
        },
        {
          "name": "Own Brand Session - E-cigarette/Cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 48,
      "start_date": "2019-01-18",
      "completion_date": "2020-03-06",
      "has_results": true,
      "last_update_posted_date": "2021-06-04",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03830892"
    },
    {
      "nct_id": "NCT00593099",
      "title": "A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Affective Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Bipolar Disorder"
      ],
      "interventions": [
        {
          "name": "Bupropion",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 5,
      "start_date": "2004-04",
      "completion_date": "2006-06",
      "has_results": false,
      "last_update_posted_date": "2017-01-11",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00593099"
    },
    {
      "nct_id": "NCT01048957",
      "title": "The Neural Basis of Cue-Elicited Cigarette Craving and Its Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Real Time Feedback Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 79,
      "start_date": "2007-01-09",
      "completion_date": "2013-04-08",
      "has_results": false,
      "last_update_posted_date": "2019-12-16",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01048957"
    },
    {
      "nct_id": "NCT04332926",
      "title": "Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "Tobacco product administration and assessment, own brand cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine",
          "type": "OTHER"
        },
        {
          "name": "Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine",
          "type": "OTHER"
        },
        {
          "name": "Tobacco product administration and assessment, ECIG 30 Watts, 15 mg/ml nicotine",
          "type": "OTHER"
        },
        {
          "name": "Tobacco product administration and assessment, ECIG 30 Watts, 30 mg/ml nicotine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 44,
      "start_date": "2021-01-05",
      "completion_date": "2023-09-08",
      "has_results": true,
      "last_update_posted_date": "2025-02-13",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04332926"
    },
    {
      "nct_id": "NCT01393301",
      "title": "Integrated Treatment for Smoking Cessation & Anxiety in People With HIV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Symptoms of Anxiety",
        "HIV"
      ],
      "interventions": [
        {
          "name": "Integrated cognitive-behavioral therapy for smoking cessation and anxiety",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 72,
      "start_date": "2011-10",
      "completion_date": "2015-05",
      "has_results": true,
      "last_update_posted_date": "2023-05-03",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01393301"
    },
    {
      "nct_id": "NCT07129265",
      "title": "Understanding Vape Marketing Study",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "E-cigarette",
        "Vaping",
        "Tobacco",
        "Nicotine",
        "Adolescent Behavior",
        "Video Information",
        "Digital Education Interventions"
      ],
      "interventions": [
        {
          "name": "Working group",
          "type": "OTHER"
        },
        {
          "name": "Focus group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2025-08-04",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-19",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07129265"
    },
    {
      "nct_id": "NCT02520349",
      "title": "Lab to Real World Assessment of E-cigarette Abuse Liability and Appeal",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "MarkTen and e-Go e-cigarettes",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Truth Initiative",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 80,
      "start_date": "2016-05",
      "completion_date": "2018-08-31",
      "has_results": false,
      "last_update_posted_date": "2020-10-06",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Richmond, Virginia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02520349"
    },
    {
      "nct_id": "NCT01216904",
      "title": "Nicotine Treatment of Impulsivity in Parkinson's Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Vermont",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2010-10",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2013-05-14",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01216904"
    },
    {
      "nct_id": "NCT05327452",
      "title": "Testing Home-based Exercise Strategies in Underserved Minority Cancer Patients Undergoing Chemotherapy: the THRIVE Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Colorectal Cancer",
        "Prostate Cancer"
      ],
      "interventions": [
        {
          "name": "Supervised Home-Based Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Unsupervised Home-Based Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Dana-Farber Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 135,
      "start_date": "2022-10-31",
      "completion_date": "2027-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05327452"
    },
    {
      "nct_id": "NCT00325611",
      "title": "Multidisciplinary Inpatient Palliative Care Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cerebrovascular Accident",
        "Cancer",
        "Coronary Arteriosclerosis",
        "Heart Failure, Congestive",
        "Diabetes Mellitus",
        "Acquired Immunodeficiency Syndrome",
        "Failure to Thrive",
        "Pulmonary Disease, Chronic Obstructive",
        "Dementia",
        "Kidney Failure, Chronic",
        "Pneumonia",
        "Liver Failure",
        "Renal Failure",
        "Respiratory Failure",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Multidisciplinary palliative care team met with patient",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 550,
      "start_date": "2002-04",
      "completion_date": "2004-07",
      "has_results": false,
      "last_update_posted_date": "2006-05-15",
      "last_synced_at": "2026-06-10T03:35:29.707Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00325611"
    }
  ]
}