{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nicotine+Addiction&page=6",
    "query": {
      "condition": "Nicotine Addiction",
      "page": 6
    },
    "page_size": 10
  },
  "pagination": {
    "page": 6,
    "page_size": 10,
    "total_count": 497,
    "total_pages": 50,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nicotine+Addiction&page=7&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nicotine+Addiction&page=5&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T12:46:20.285Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03473483",
      "title": "Cigarette Harm Reduction With Electronic Cigarette Use",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Tobacco Toxicity",
        "Nicotine Dependence, Cigarettes",
        "Cardiovascular Risk Factor",
        "Nicotine Withdrawal"
      ],
      "interventions": [
        {
          "name": "SREC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2022-08-01",
      "completion_date": "2026-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-12-09",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03473483"
    },
    {
      "nct_id": "NCT04188873",
      "title": "Cessation Screening Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Preparation Varenicline and Standard Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Preparation Varenicline and Extended Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Standard Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Extended Duration Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Preparation Combination NRT and Standard Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Preparation Combination NRT and Extended Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Standard Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Extended Duration Combination NRT",
          "type": "DRUG"
        },
        {
          "name": "Intensive Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 538,
      "start_date": "2020-12-10",
      "completion_date": "2025-05-08",
      "has_results": true,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04188873"
    },
    {
      "nct_id": "NCT00297453",
      "title": "Smoking Treatment in HIV Clinical Care Settings",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Internet-based smoking treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Individual Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "self-help",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 207,
      "start_date": "2006-01",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2012-06-27",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00297453"
    },
    {
      "nct_id": "NCT06688539",
      "title": "E-cigarette Cessation in Adults Who Co-use Cannabis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "Varenicline Pill",
          "type": "DRUG"
        },
        {
          "name": "Contingency management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 105,
      "start_date": "2025-02-19",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-12",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 3,
      "location_summary": "Charleston, South Carolina • Lancaster, South Carolina • Pickens, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Lancaster",
          "state": "South Carolina"
        },
        {
          "city": "Pickens",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06688539"
    },
    {
      "nct_id": "NCT00996034",
      "title": "Nicotine Vaccination and Nicotinic Receptor Occupancy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "NicVAX",
          "type": "BIOLOGICAL"
        },
        {
          "name": "[123I]5-IA-85380",
          "type": "RADIATION"
        },
        {
          "name": "Nicotine bitartrate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "RADIATION",
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 14,
      "start_date": "2009-09",
      "completion_date": "2011-02",
      "has_results": true,
      "last_update_posted_date": "2015-12-24",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00996034"
    },
    {
      "nct_id": "NCT02487953",
      "title": "Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "ENDS",
          "type": "OTHER"
        },
        {
          "name": "Placebo patch",
          "type": "OTHER"
        },
        {
          "name": "Placebo ENDS",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-07",
      "completion_date": "2022-01",
      "has_results": false,
      "last_update_posted_date": "2018-09-12",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02487953"
    },
    {
      "nct_id": "NCT03077737",
      "title": "Reducing Tobacco Use Disparities Among Low-Income Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Choose to Change",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced usual care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 190,
      "start_date": "2017-04-21",
      "completion_date": "2018-08-31",
      "has_results": true,
      "last_update_posted_date": "2022-01-21",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03077737"
    },
    {
      "nct_id": "NCT00969137",
      "title": "Sensitivity to Intravenous Nicotine: Genetic Moderators",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "saline",
          "type": "DRUG"
        },
        {
          "name": "Nicotine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 213,
      "start_date": "2009-06-02",
      "completion_date": "2016-06-01",
      "has_results": false,
      "last_update_posted_date": "2017-04-19",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00969137"
    },
    {
      "nct_id": "NCT01867411",
      "title": "Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 159,
      "start_date": "2013-11-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-09-24",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01867411"
    },
    {
      "nct_id": "NCT02986711",
      "title": "Penn State TXT2STAYQUIT Study- a Texting Study to Help Hospitalized Smokers Stay Quit",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence, Cigarettes"
      ],
      "interventions": [
        {
          "name": "Motivational Text Messages",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 158,
      "start_date": "2013-12",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2018-12-19",
      "last_synced_at": "2026-10-23T12:46:20.285Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02986711"
    }
  ]
}