{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nicotine+Exposure", "query": { "condition": "Nicotine Exposure" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 62, "total_pages": 7, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Nicotine+Exposure&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-22T08:57:13.120Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04019626", "title": "A Study to Assess Tobacco-related Biomarkers of Exposure in Smokers Using myBlu E-cigarettes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Continue-smoking", "type": "OTHER" }, { "name": "myblu Tobacco 2.5%", "type": "OTHER" }, { "name": "myblu Tobacco 4.0%", "type": "OTHER" }, { "name": "myblu Honeymoon 2.5%", "type": "OTHER" }, { "name": "myblu Honeymoon 4.0%", "type": "OTHER" }, { "name": "JUUL 5%", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Fontem Ventures BV", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 240, "start_date": "2019-03-01", "completion_date": "2020-12-31", "has_results": true, "last_update_posted_date": "2021-06-30", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 1, "location_summary": "Lincoln, Nebraska", "locations": [ { "city": "Lincoln", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT04019626" }, { "nct_id": "NCT00118534", "title": "Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Mental Health", "Stress Disorders, Post-Traumatic", "Substance-Related Disorders", "Tobacco Use Disorder" ], "interventions": [ { "name": "Integrated Care for Smoking Cessation in PTSD patients", "type": "BEHAVIORAL" }, { "name": "Standard of Care", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "US Department of Veterans Affairs", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 943, "start_date": "2004-07", "completion_date": "2009-06", "has_results": true, "last_update_posted_date": "2014-05-05", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 11, "location_summary": "Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more", "locations": [ { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "San Diego", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00118534" }, { "nct_id": "NCT00586482", "title": "Pilot Study: Preoperative Nicotine Lozenges", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking" ], "interventions": [ { "name": "Nicotine Lozenge", "type": "DRUG" }, { "name": "Placebo Lozenge", "type": "DRUG" }, { "name": "Abstinence Advisement", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 46, "start_date": "2006-08", "completion_date": "2013-01", "has_results": true, "last_update_posted_date": "2014-12-22", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00586482" }, { "nct_id": "NCT04107779", "title": "Changes in Biomarkers of Cigarette Smoke Exposure After Switching Either Exclusively or Partly to JUUL ENDS", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Electronic Cigarette Use", "Cigarette Use, Electronic", "Tobacco Use", "Tobacco Smoking" ], "interventions": [ { "name": "Switch from UB of Combustible Cigarette to JUUL 5% Virginia Tobacco ENDS", "type": "OTHER" }, { "name": "Switch from UB of Combustible Cigarette to JUUL 3% Virginia Tobacco ENDS", "type": "OTHER" }, { "name": "Switch from UB of Combustible Cigarette to JUUL 5% Mint ENDS", "type": "OTHER" }, { "name": "Switch from UB of Combustible Cigarette to JUUL 3% Mint ENDS", "type": "OTHER" }, { "name": "Switch from UB of Combustible Cigarette to JUUL 5% Menthol ENDS", "type": "OTHER" }, { "name": "Switch from UB of Combustible Cigarette to JUUL 3% Menthol ENDS", "type": "OTHER" }, { "name": "Switch from UB of Combustible Cigarette to JUUL 5% Mango ENDS", "type": "OTHER" }, { "name": "Switch from UB of Combustible Cigarette to JUUL 3% Mango ENDS", "type": "OTHER" }, { "name": "Switch to Dual-use of JUUL 5% and UB of Combustible Cigarette", "type": "OTHER" }, { "name": "Tobacco/Nicotine Abstention", "type": "OTHER" }, { "name": "Usual Brand of cigarettes", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Juul Labs, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 279, "start_date": "2019-09-17", "completion_date": "2020-06-24", "has_results": false, "last_update_posted_date": "2020-07-28", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 5, "location_summary": "Little Rock, Arkansas • Rogers, Arkansas • St Louis, Missouri + 2 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Dayton", "state": "Ohio" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04107779" }, { "nct_id": "NCT03786042", "title": "Trial on the Effect of E-cigarette Advertising on Cigarette Perceptions in Adolescents", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Attentional Bias", "Smoking Cues", "Positive Perceptions About Cigarette Smoking", "Social Norms", "Smoking Susceptibility" ], "interventions": [ { "name": "E-cigarette ad exposure", "type": "BEHAVIORAL" }, { "name": "non e-cigarette TV commercials", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "Trustees of Dartmouth College", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "14 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "14 Years to 17 Years" }, "enrollment_count": 139, "start_date": "2019-02-04", "completion_date": "2021-12-09", "has_results": true, "last_update_posted_date": "2025-09-26", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 1, "location_summary": "Lebanon, New Hampshire", "locations": [ { "city": "Lebanon", "state": "New Hampshire" } ], "official_url": "https://clinicaltrials.gov/study/NCT03786042" }, { "nct_id": "NCT04090879", "title": "Low Nicotine Content Cigarettes in Vulnerable Populations: Affective Disorders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Tobacco Use Disorder" ], "interventions": [ { "name": "Either normal nicotine content cigarettes (15.8mg/g) or reduced nicotine content cigarettes (0.4mg/g)", "type": "OTHER" }, { "name": "E-Cigarettes", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Brown University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 326, "start_date": "2020-10-18", "completion_date": "2023-11-27", "has_results": true, "last_update_posted_date": "2025-04-01", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 2, "location_summary": "Providence, Rhode Island • Burlington, Vermont", "locations": [ { "city": "Providence", "state": "Rhode Island" }, { "city": "Burlington", "state": "Vermont" } ], "official_url": "https://clinicaltrials.gov/study/NCT04090879" }, { "nct_id": "NCT03802019", "title": "Cigarette Packaging of Low Nicotine Cigarettes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking, Cigarette" ], "interventions": [ { "name": "LNC Cigarettes + Colored Packaging", "type": "OTHER" }, { "name": "Own Brand", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Abramson Cancer Center at Penn Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 219, "start_date": "2019-09-18", "completion_date": "2025-08-27", "has_results": false, "last_update_posted_date": "2026-02-23", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03802019" }, { "nct_id": "NCT05447325", "title": "Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Escalation in Young Adult ENDS Users", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Message Exposure (Sequence: Regular Then Flavor)", "Message Exposure (Sequence: Flavor Then Regular)", "No Message Exposure (Control Condition)" ], "interventions": [ { "name": "Exposure to Anti-Vaping Messages (generic themes then flavor-specific themes)", "type": "BEHAVIORAL" }, { "name": "Exposure to Anti-Vaping Messages (flavor-specific themes then generic themes)", "type": "BEHAVIORAL" }, { "name": "Exposure to Anti-Vaping Messages (no message exposure)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Georgia", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "29 Years", "sex": "ALL", "summary": "18 Years to 29 Years" }, "enrollment_count": 180, "start_date": "2022-07-15", "completion_date": "2026-07-31", "has_results": false, "last_update_posted_date": "2026-04-03", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 1, "location_summary": "Athens, Georgia", "locations": [ { "city": "Athens", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05447325" }, { "nct_id": "NCT04429932", "title": "A Study to Evaluate Nicotine Uptake and Biomarkers in Adult Smokers Using mybluTM Electronic Cigarettes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "Myblu flavor A_2.4", "type": "OTHER" }, { "name": "Myblu flavor B_2.4", "type": "OTHER" }, { "name": "Myblu flavor C_2.4", "type": "OTHER" }, { "name": "Myblu flavor D_2.4", "type": "OTHER" }, { "name": "Myblu flavor E_1.2", "type": "OTHER" }, { "name": "Myblu flavor F_1.2", "type": "OTHER" }, { "name": "Myblu flavor G_2.4", "type": "OTHER" }, { "name": "Myblu flavor H_2.4", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Fontem US LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 39, "start_date": "2019-12-01", "completion_date": "2020-01-31", "has_results": true, "last_update_posted_date": "2021-06-07", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 1, "location_summary": "Lincoln, Nebraska", "locations": [ { "city": "Lincoln", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT04429932" }, { "nct_id": "NCT03492463", "title": "The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nicotine Dependence, Cigarettes" ], "interventions": [ { "name": "Nicotine patch", "type": "DRUG" }, { "name": "Placebo patch", "type": "OTHER" }, { "name": "E-cigarettes", "type": "OTHER" }, { "name": "Non-nicotine e-cigarettes", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 94, "start_date": "2018-08-06", "completion_date": "2021-05-31", "has_results": true, "last_update_posted_date": "2023-02-08", "last_synced_at": "2026-07-22T08:57:13.120Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03492463" } ] }