{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-24+Hour+Sleep-Wake+Disorder",
    "query": {
      "condition": "Non-24 Hour Sleep-Wake Disorder"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:39:05.981Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00972075",
      "title": "Efficacy and Safety of Circadin for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Non-24 Hour Sleep-Wake Disorder",
        "Blindness"
      ],
      "interventions": [
        {
          "name": "melatonin (Circadin)",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Neurim Pharmaceuticals Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "20 Years to 80 Years"
      },
      "enrollment_count": 13,
      "start_date": "2006-02",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2009-09-09",
      "last_synced_at": "2026-05-22T03:39:05.981Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia • New York, New York",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00972075"
    },
    {
      "nct_id": "NCT02776215",
      "title": "Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Circadian Rhythm Sleep Disorders",
        "Non-24 Hour Sleep-Wake Disorder",
        "Autism Spectrum Disorder",
        "Smith-Magenis Syndrome"
      ],
      "interventions": [
        {
          "name": "tasimelteon",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanda Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 24,
      "start_date": "2016-10-04",
      "completion_date": "2017-12-20",
      "has_results": false,
      "last_update_posted_date": "2024-03-21",
      "last_synced_at": "2026-05-22T03:39:05.981Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02776215"
    },
    {
      "nct_id": "NCT01429116",
      "title": "Tasimelteon for the Treatment of Non-24-hour Sleep-Wake Disorder (N24HSWD) in Blind Individuals With no Light Perception",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Non-24-Hour Sleep-Wake Disorder"
      ],
      "interventions": [
        {
          "name": "tasimelteon",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanda Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2011-10",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2015-04-21",
      "last_synced_at": "2026-05-22T03:39:05.981Z",
      "location_count": 22,
      "location_summary": "Phoenix, Arizona • Orange, California • Palo Alto, California + 19 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01429116"
    },
    {
      "nct_id": "NCT03980340",
      "title": "Breath Biomarkers for Sleep Loss and Circadian Timing",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Shift-Work Sleep Disorder",
        "Shift Work Type Circadian Rhythm Sleep Disorder",
        "Sleep Disorders, Circadian Rhythm",
        "Sleep Disorders, Intrinsic",
        "Advanced Sleep Phase Syndrome (ASPS)",
        "Advanced Sleep Phase Syndrome",
        "Advanced Sleep Phase",
        "Delayed Sleep Phase",
        "Delayed Sleep Phase Syndrome",
        "Non-24 Hour Sleep-Wake Disorder",
        "Irregular Sleep-Wake Syndrome"
      ],
      "interventions": [
        {
          "name": "Short Nap Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No Nap Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 5,
      "start_date": "2021-01-28",
      "completion_date": "2025-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-03",
      "last_synced_at": "2026-05-22T03:39:05.981Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03980340"
    },
    {
      "nct_id": "NCT01430754",
      "title": "Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Non-24-Hour Sleep-Wake Disorder"
      ],
      "interventions": [
        {
          "name": "tasimelteon",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanda Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2011-09",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2014-10-10",
      "last_synced_at": "2026-05-22T03:39:05.981Z",
      "location_count": 22,
      "location_summary": "Phoenix, Arizona • Orange, California • Palo Alto, California + 19 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01430754"
    },
    {
      "nct_id": "NCT01163032",
      "title": "Efficacy and Safety of Tasimelteon Compared With Placebo in Totally Blind Subjects With Non-24-Hour Sleep-Wake Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Non-24-Hour Sleep-Wake Disorder"
      ],
      "interventions": [
        {
          "name": "tasimelteon",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanda Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 136,
      "start_date": "2010-08",
      "completion_date": "2012-11",
      "has_results": true,
      "last_update_posted_date": "2014-10-16",
      "last_synced_at": "2026-05-22T03:39:05.981Z",
      "location_count": 23,
      "location_summary": "Phoenix, Arizona • Orange, California • Palo Alto, California + 20 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01163032"
    },
    {
      "nct_id": "NCT03956745",
      "title": "Biomarkers for Circadian Timing in Healthy Adults",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sleep Wake Disorders",
        "Sleep Disorders, Circadian Rhythm",
        "Sleep Disorders, Intrinsic",
        "Advanced Sleep Phase Syndrome (ASPS)",
        "Advanced Sleep Phase Syndrome",
        "Advanced Sleep Phase",
        "Delayed Sleep Phase",
        "Delayed Sleep Phase Syndrome",
        "Non-24 Hour Sleep-Wake Disorder",
        "Irregular Sleep-Wake Syndrome",
        "Shift-Work Sleep Disorder",
        "Shift Work Type Circadian Rhythm Sleep Disorder",
        "Delayed Phase Sleep Syndrome"
      ],
      "interventions": [
        {
          "name": "sleep-wake timing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "constant routine",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 15,
      "start_date": "2021-06-01",
      "completion_date": "2025-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-03",
      "last_synced_at": "2026-05-22T03:39:05.981Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03956745"
    }
  ]
}