{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-Union+Fracture&page=2",
    "query": {
      "condition": "Non-Union Fracture",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-Union+Fracture&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T01:34:40.659Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05699174",
      "title": "PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infections",
        "Infected Wound",
        "Nonunion of Fracture",
        "Injury Leg",
        "Amputation",
        "Internal Fixation; Complications, Infection or Inflammation",
        "Fracture",
        "Lower Extremity Fracture",
        "Antibiotic Side Effect"
      ],
      "interventions": [
        {
          "name": "Standard of Care PO (oral) antibiotics",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care Intravenous (IV) antibiotics",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Major Extremity Trauma Research Consortium",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2023-05-30",
      "completion_date": "2027-09-29",
      "has_results": false,
      "last_update_posted_date": "2026-02-02",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 13,
      "location_summary": "Indianapolis, Indiana • Baltimore, Maryland • Minneapolis, Minnesota + 9 more",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Queens",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05699174"
    },
    {
      "nct_id": "NCT03382483",
      "title": "Observational, Non-interventional Use of LIPUS to Mitigate Fracture Non-union in Patients at Risk",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mitigation of Fracture Non-union in Patients at Risk"
      ],
      "interventions": [
        {
          "name": "Low intensity pulsed ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bioventus LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 12387,
      "start_date": "2017-10-16",
      "completion_date": "2022-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-28",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 1,
      "location_summary": "Jericho, New York",
      "locations": [
        {
          "city": "Jericho",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03382483"
    },
    {
      "nct_id": "NCT07280169",
      "title": "Carbo-fix Lateral Plate Devices and Standard Plate-Nail Constructs in Distal Femur Fractures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Distal Femur Fracture"
      ],
      "interventions": [
        {
          "name": "Carbo-fix Lateral Plate Device",
          "type": "DEVICE"
        },
        {
          "name": "Standard Plate-Nail Construct",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-01-29",
      "completion_date": "2029-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07280169"
    },
    {
      "nct_id": "NCT04299022",
      "title": "Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fractures, Bone",
        "Nonunion of Fracture",
        "Fractures, Open",
        "Fractures, Ununited",
        "Fracture, Tibial",
        "Fracture of Femur",
        "Fracture Arm"
      ],
      "interventions": [
        {
          "name": "Vivigen Cellular Bone Matrix",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "LifeNet Health",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 250,
      "start_date": "2021-06-01",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-04-02",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 4,
      "location_summary": "Orlando, Florida • Jersey City, New Jersey • Durham, North Carolina + 1 more",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Jersey City",
          "state": "New Jersey"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04299022"
    },
    {
      "nct_id": "NCT02783274",
      "title": "Actis Total Hip System 2 Year Follow-up",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Traumatic Arthritis",
        "Rheumatoid Arthritis",
        "Congenital Hip Dysplasia",
        "Avascular Necrosis of the Femoral Head",
        "Acute Traumatic Fracture of the Femoral Head or Neck",
        "Certain Cases of Ankylosis",
        "Non-union of Femoral Neck Fractures",
        "Certain High Sub-Capital & Femoral Neck Fractures in Elderly"
      ],
      "interventions": [
        {
          "name": "Actis Total Hip System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 266,
      "start_date": "2016-07-01",
      "completion_date": "2024-03-13",
      "has_results": true,
      "last_update_posted_date": "2025-08-15",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 9,
      "location_summary": "Louisville, Kentucky • Boston, Massachusetts • Rochester, Minnesota + 6 more",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02783274"
    },
    {
      "nct_id": "NCT00556543",
      "title": "Clinical Study of the U-Plate Fracture Repair System to Treat Rib Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rib Fracture",
        "Flail Chest"
      ],
      "interventions": [
        {
          "name": "U-plate fracture repair system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2006-11",
      "completion_date": "2008-10",
      "has_results": true,
      "last_update_posted_date": "2011-07-01",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00556543"
    },
    {
      "nct_id": "NCT03937310",
      "title": "NGS for Non-unions",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nonunion of Fracture"
      ],
      "interventions": [
        {
          "name": "Next-generation sequencing of swabs collected during surgery",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Rothman Institute Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2019-01-03",
      "completion_date": "2022-02-03",
      "has_results": false,
      "last_update_posted_date": "2019-05-03",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03937310"
    },
    {
      "nct_id": "NCT04964947",
      "title": "Tobramycin Injection to Prevent Infection in Open Fractures",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Wound Infection",
        "Fractures, Open",
        "Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "Tobramycin Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 600,
      "start_date": "2022-01-10",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 3,
      "location_summary": "Lexington, Kentucky • Boston, Massachusetts • Nashville, Tennessee",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04964947"
    },
    {
      "nct_id": "NCT06872775",
      "title": "855303-RNA Biomarker Validation",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fractures, Bone"
      ],
      "interventions": [
        {
          "name": "Blood draws to assess RNA expression levels",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2025-08-25",
      "completion_date": "2028-08-24",
      "has_results": false,
      "last_update_posted_date": "2026-01-16",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 7,
      "location_summary": "Sacramento, California • Bloomington, Indiana • Columbia, Missouri + 4 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Bloomington",
          "state": "Indiana"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06872775"
    },
    {
      "nct_id": "NCT00424567",
      "title": "Feasibility Study of Aastrom Tissue Repair Cells to Treat Non-Union Fractures.",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Fracture, Ununited",
        "Pseudarthrosis"
      ],
      "interventions": [
        {
          "name": "Fracture surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Cultured Bone Marrow Tissue",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Vericel Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2003-10",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2021-05-11",
      "last_synced_at": "2026-06-11T01:34:40.659Z",
      "location_count": 4,
      "location_summary": "Des Plaines, Illinois • Ann Arbor, Michigan • Royal Oak, Michigan + 1 more",
      "locations": [
        {
          "city": "Des Plaines",
          "state": "Illinois"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00424567"
    }
  ]
}