{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-fluent+Aphasia",
    "query": {
      "condition": "Non-fluent Aphasia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-fluent+Aphasia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:11:20.999Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00903266",
      "title": "Melodic-Intonation-Therapy and Speech-Repetition-Therapy for Patients With Non-fluent Aphasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Aphasia",
        "Stroke",
        "Cerebrovascular Accident",
        "Apoplexy",
        "Cerebral Infarction"
      ],
      "interventions": [
        {
          "name": "Melodic Intonation Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Speech-Repetition-Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2008-02",
      "completion_date": "2020-06",
      "has_results": false,
      "last_update_posted_date": "2020-09-21",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00903266"
    },
    {
      "nct_id": "NCT02226796",
      "title": "Transcranial Direct Stimulation (tDCS) and Behavioral Intervention in Aphasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aphasia"
      ],
      "interventions": [
        {
          "name": "Transcranial direct current stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "20 Years to 85 Years"
      },
      "enrollment_count": 3,
      "start_date": "2015-09-01",
      "completion_date": "2018-12-01",
      "has_results": true,
      "last_update_posted_date": "2022-10-18",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02226796"
    },
    {
      "nct_id": "NCT01674868",
      "title": "Fluoxetine for Motor, Aphasia, and Neglect Recovery After Ischemic Stroke",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "fluoxetine",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 0,
      "start_date": "2013-04",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2015-06-16",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01674868"
    },
    {
      "nct_id": "NCT02365922",
      "title": "Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "FTLD",
        "Progressive Supranuclear Palsy (PSP)",
        "Frontotemporal Dementia (FTD)",
        "Corticobasal Degeneration (CBD)",
        "PPA Syndrome",
        "Behavioral Variant Frontotemporal Dementia (bvFTD)",
        "Semantic Variant Primary Progressive Aphasia (svPPA)",
        "Nonfluent Variant Primary Progressive Aphasia (nfvPPA)",
        "FTD With Amyotrophic Lateral Sclerosis (FTD/ALS)",
        "Amyotrophic Lateral Sclerosis (ALS)",
        "Oligosymptomatic PSP (oPSP)",
        "Corticobasal Syndrome (CBS)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 1489,
      "start_date": "2014-09",
      "completion_date": "2020-09",
      "has_results": false,
      "last_update_posted_date": "2021-05-21",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 15,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • San Diego, California + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02365922"
    },
    {
      "nct_id": "NCT01623284",
      "title": "PiB PET Scanning in Speech and Language Based Dementias",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "PPA",
        "Primary Progressive Aphasia",
        "Aphasia",
        "Non-fluent Aphasia",
        "Semantic Dementia",
        "Apraxia of Speech",
        "Primary Progressive Nonfluent Aphasia",
        "Progressive Aphasia"
      ],
      "interventions": [
        {
          "name": "C-11 PiB",
          "type": "DRUG"
        },
        {
          "name": "F-18 FDG",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 168,
      "start_date": "2010-03",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2015-12-22",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01623284"
    },
    {
      "nct_id": "NCT04881617",
      "title": "Treatment for Speech and Language in Primary Progressive Aphasia",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Progressive Aphasia",
        "Semantic Dementia",
        "Semantic Memory Disorder",
        "Logopenic Progressive Aphasia",
        "Nonfluent Aphasia, Progressive",
        "Aphasia",
        "Aphasia, Progressive"
      ],
      "interventions": [
        {
          "name": "Lexical Retrieval Training (LRT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Video-Implemented Script Training for Aphasia (VISTA)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 60,
      "start_date": "2017-07-01",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-13",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Austin, Texas",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04881617"
    },
    {
      "nct_id": "NCT00537004",
      "title": "Language in Primary Progressive Aphasia",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Progressive Aphasia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 500,
      "start_date": "2007-05",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00537004"
    },
    {
      "nct_id": "NCT06829420",
      "title": "Mirror Speech Entrainment: A Novel Technique for Voice Personalized Speech Entrainment for Nonfluent Aphasia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aphasia Non Fluent",
        "Stroke",
        "Aphasia"
      ],
      "interventions": [
        {
          "name": "Mirror speech entrainment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Traditional speech entrainment: auditory-only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Traditional speech entrainment: auditory-visual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2025-05-01",
      "completion_date": "2027-08-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-21",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 2,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06829420"
    },
    {
      "nct_id": "NCT03658135",
      "title": "BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TES",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Primary Tauopathies",
        "Corticobasal Degeneration Syndrome",
        "Frontotemporal Lobar Degeneration With Tau Inclusions",
        "MAPT Mutation Carriers, Symptomatic",
        "Traumatic Encephalopathy Syndrome",
        "Nonfluent Aphasia, Progressive"
      ],
      "interventions": [
        {
          "name": "BIIB092",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "35 Years to 80 Years"
      },
      "enrollment_count": 22,
      "start_date": "2018-09-12",
      "completion_date": "2019-12-13",
      "has_results": false,
      "last_update_posted_date": "2019-12-19",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03658135"
    },
    {
      "nct_id": "NCT03406429",
      "title": "rTMS as a Treatment for PPA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Logopenic Variant Primary Progressive Aphasia",
        "Non-Fluent Primary Progressive Aphasia"
      ],
      "interventions": [
        {
          "name": "Active rTMS",
          "type": "DEVICE"
        },
        {
          "name": "SHAM rTMS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 12,
      "start_date": "2019-12-01",
      "completion_date": "2022-01-01",
      "has_results": false,
      "last_update_posted_date": "2022-04-07",
      "last_synced_at": "2026-05-22T08:11:20.999Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03406429"
    }
  ]
}