{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-inferiority+Trial",
    "query": {
      "condition": "Non-inferiority Trial"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 178,
    "total_pages": 18,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-inferiority+Trial&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T05:59:33.185Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03341273",
      "title": "Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin Level",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Respiratory Tract Infection"
      ],
      "interventions": [
        {
          "name": "Azithromycin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "VIDAS B.R.A.H.M.S Procalcitonin Test (PCT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 514,
      "start_date": "2017-12-08",
      "completion_date": "2020-08-15",
      "has_results": true,
      "last_update_posted_date": "2023-06-28",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 5,
      "location_summary": "Atlanta, Georgia • Decatur, Georgia • Durham, North Carolina + 1 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Decatur",
          "state": "Georgia"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03341273"
    },
    {
      "nct_id": "NCT05867654",
      "title": "Efficacy of Oral vs IV Antibiotics in the Treatment of Orofacial Osteomyelitis",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Osteomyelitis of Jaw"
      ],
      "interventions": [
        {
          "name": "Amoxicillin-clavulanate 875mg/125mg q12hrs",
          "type": "DRUG"
        },
        {
          "name": "oral clindamycin 300mg q6hrs",
          "type": "DRUG"
        },
        {
          "name": "Levofloxacin 750mg QID",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 100,
      "start_date": "2024-07-31",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2024-07-17",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05867654"
    },
    {
      "nct_id": "NCT03938688",
      "title": "Randomized Control Trial Comparing Transfascial Suture for Mesh Fixation to No Mesh Fixation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventral Hernia",
        "Incisional Hernia"
      ],
      "interventions": [
        {
          "name": "Mesh placement with Transfascial Sutures",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 325,
      "start_date": "2019-10-21",
      "completion_date": "2022-12-18",
      "has_results": false,
      "last_update_posted_date": "2023-06-22",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03938688"
    },
    {
      "nct_id": "NCT03776162",
      "title": "A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear"
      ],
      "interventions": [
        {
          "name": "ACL Reconstruction (Bone Patellar Tendon Bone Graft)",
          "type": "PROCEDURE"
        },
        {
          "name": "Bridge Enhanced ACL Restoration (BEAR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 150,
      "start_date": "2021-08-30",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-07-29",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 6,
      "location_summary": "Boulder, Colorado • Bloomington, Minnesota • Cleveland, Ohio + 3 more",
      "locations": [
        {
          "city": "Boulder",
          "state": "Colorado"
        },
        {
          "city": "Bloomington",
          "state": "Minnesota"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03776162"
    },
    {
      "nct_id": "NCT00094523",
      "title": "Fosamprenavir Versus Other Protease Inhibitors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infection, Human Immunodeficiency Virus I"
      ],
      "interventions": [
        {
          "name": "Fosamprenavir",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "ViiV Healthcare",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 314,
      "start_date": "2004-12-14",
      "completion_date": "2007-06-29",
      "has_results": false,
      "last_update_posted_date": "2018-04-18",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 51,
      "location_summary": "Beverly Hills, California • Fresno, California • Laguna Beach, California + 42 more",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Laguna Beach",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00094523"
    },
    {
      "nct_id": "NCT06721520",
      "title": "Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Esophageal Cancer Surgery",
        "Esophagectomy",
        "Delayed Gastric Emptying Following Procedure",
        "Esophageal Diseases",
        "Esophageal Achalasia",
        "Pylorus Dysfunction",
        "Esophageal Dysmotility"
      ],
      "interventions": [
        {
          "name": "Botulinum Toxin A (Botox )",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pyloromyotomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 170,
      "start_date": "2024-12-03",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-25",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06721520"
    },
    {
      "nct_id": "NCT07049276",
      "title": "The Multicentre Selective Lymphadenectomy Trial - 3",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cutaneous Melanoma, Stage III"
      ],
      "interventions": [
        {
          "name": "Index lymph node resection",
          "type": "PROCEDURE"
        },
        {
          "name": "Therapeutic lymph node dissection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Melanoma Institute Australia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1500,
      "start_date": "2025-10-01",
      "completion_date": "2040-08",
      "has_results": false,
      "last_update_posted_date": "2026-06-29",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07049276"
    },
    {
      "nct_id": "NCT06393725",
      "title": "Synchronous vs Asynchronous Remotely Delivered Lifestyle Interventions",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Asynchronous Remote Lifestyle Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Synchronous Remote Lifestyle Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Connecticut",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 328,
      "start_date": "2025-02-06",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-12",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 1,
      "location_summary": "Storrs, Connecticut",
      "locations": [
        {
          "city": "Storrs",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06393725"
    },
    {
      "nct_id": "NCT03140423",
      "title": "Mupirocin-Iodophor ICU Decolonization Swap Out Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Staphylococcus Aureus"
      ],
      "interventions": [
        {
          "name": "Arm 1. Routine Care (Mupirocin/CHG)",
          "type": "DRUG"
        },
        {
          "name": "Arm 2. Iodophor/CHG Decolonization",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Harvard Pilgrim Health Care",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 353323,
      "start_date": "2017-05-01",
      "completion_date": "2023-11-06",
      "has_results": true,
      "last_update_posted_date": "2025-03-30",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 137,
      "location_summary": "Riverside, California • San Jose, California • Thousand Oaks, California + 103 more",
      "locations": [
        {
          "city": "Riverside",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Thousand Oaks",
          "state": "California"
        },
        {
          "city": "West Hills",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03140423"
    },
    {
      "nct_id": "NCT03445676",
      "title": "Effectiveness of an Alcohol-based Hand Rub to \"Clean\" Gloved Hands",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hand Hygiene"
      ],
      "interventions": [
        {
          "name": "ABHR directly on gloves",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1450,
      "start_date": "2017-03-15",
      "completion_date": "2019-01-01",
      "has_results": false,
      "last_update_posted_date": "2020-05-07",
      "last_synced_at": "2026-07-23T05:59:33.185Z",
      "location_count": 3,
      "location_summary": "Iowa City, Iowa • Baltimore, Maryland",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03445676"
    }
  ]
}