{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-inflammatory+Degenerative+Joint+Disease&page=2",
    "query": {
      "condition": "Non-inflammatory Degenerative Joint Disease",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-inflammatory+Degenerative+Joint+Disease&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T06:28:25.815Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01543230",
      "title": "CoMplete™ Acetabular Hip System",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-inflammatory Degenerative Joint Disease",
        "Osteoarthritis",
        "Post-traumatic Arthritis"
      ],
      "interventions": [
        {
          "name": "Total hip replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 58,
      "start_date": "2012-02",
      "completion_date": "2013-10",
      "has_results": false,
      "last_update_posted_date": "2014-04-08",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 6,
      "location_summary": "Little Rock, Arkansas • Orange, California • Fort Collins, Colorado + 3 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01543230"
    },
    {
      "nct_id": "NCT04391842",
      "title": "Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Osteo Arthritis Knee",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Device with 1% Diclofenac patch",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "45 Years to 85 Years"
      },
      "enrollment_count": 34,
      "start_date": "2019-09-01",
      "completion_date": "2019-12-31",
      "has_results": true,
      "last_update_posted_date": "2023-06-27",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 1,
      "location_summary": "Dryden, New York",
      "locations": [
        {
          "city": "Dryden",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04391842"
    },
    {
      "nct_id": "NCT00208507",
      "title": "28 mm Ceramic-on-Ceramic Acetabular Cup Total Hip Replacement Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Joint Diseases"
      ],
      "interventions": [
        {
          "name": "28 mm ceramic head on ceramic acetabular liner.",
          "type": "DEVICE"
        },
        {
          "name": "28 mm ceramic head on polyethylene liner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "20 Years to 75 Years"
      },
      "enrollment_count": 264,
      "start_date": "2003-04-01",
      "completion_date": "2012-01-05",
      "has_results": true,
      "last_update_posted_date": "2023-11-07",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 2,
      "location_summary": "Denver, Colorado • Columbus, Ohio",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00208507"
    },
    {
      "nct_id": "NCT03056534",
      "title": "R3 Delta Ceramic Acetabular System PAS U.S.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Joint Disease"
      ],
      "interventions": [
        {
          "name": "R3 Biolox Delta Ceramic Acetabular System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 189,
      "start_date": "2018-02-07",
      "completion_date": "2023-05-31",
      "has_results": true,
      "last_update_posted_date": "2025-04-13",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 8,
      "location_summary": "Tampa, Florida • Tucker, Georgia • Annapolis, Maryland + 5 more",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Tucker",
          "state": "Georgia"
        },
        {
          "city": "Annapolis",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Reno",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03056534"
    },
    {
      "nct_id": "NCT03768128",
      "title": "Safety and Performance of the Journey™ II UNI Unicompartmental Knee System",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Non-inflammatory Degenerative Joint Disease (NIDJD) of the Knee"
      ],
      "interventions": [
        {
          "name": "Journey™ II UNI Unicompartmental Knee System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 154,
      "start_date": "2018-08-10",
      "completion_date": "2025-05-19",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • Rockford, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Rockford",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03768128"
    },
    {
      "nct_id": "NCT00962351",
      "title": "Metal Ion Release From an FDA-Approved Metal-on-Metal Total Hip Replacement Implant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-inflammatory Degenerative Joint Disease"
      ],
      "interventions": [
        {
          "name": "Total Hip Replacement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Anderson Orthopaedic Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 120,
      "start_date": "2003-10",
      "completion_date": "2013-10",
      "has_results": false,
      "last_update_posted_date": "2015-08-17",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 1,
      "location_summary": "Alexandria, Virginia",
      "locations": [
        {
          "city": "Alexandria",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00962351"
    },
    {
      "nct_id": "NCT06911359",
      "title": "The Effect and Safety of Anti-inflammatories and Dextrose Prolotherapy Injections in Treating Knee Osteoarthritis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Knee Osteoarthritis (OA)"
      ],
      "interventions": [
        {
          "name": "Participants are given Ibuprofen 400 mg to take for 7 days on the day they receive a dextrose prolotherapy (DPT) injection. These procedures are repeated every 3-5 weeks for a total of 3 times.",
          "type": "DRUG"
        },
        {
          "name": "Participants are given a placebo to take for 7 days on the day they receive a dextrose prolotherapy (DPT) injection. These procedures are repeated every 3-5 weeks for a total of 3 times.",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "David Grant U.S. Air Force Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "45 Years to 75 Years"
      },
      "enrollment_count": 68,
      "start_date": "2025-03-31",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-24",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 1,
      "location_summary": "Travis AFB, California",
      "locations": [
        {
          "city": "Travis AFB",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06911359"
    },
    {
      "nct_id": "NCT00546598",
      "title": "Post-approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Non-inflammatory Joint Disease",
        "Osteoarthritis",
        "Avascular Necrosis",
        "Congenital Hip Dysplasia",
        "Post-traumatic Arthritis"
      ],
      "interventions": [
        {
          "name": "Total hip replacement/arthroplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 106,
      "start_date": "2006-01-01",
      "completion_date": "2014-04-01",
      "has_results": false,
      "last_update_posted_date": "2021-11-30",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 6,
      "location_summary": "Atlanta, Georgia • Springfield, Illinois • Cleveland, Ohio + 2 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Maumee",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00546598"
    },
    {
      "nct_id": "NCT05719935",
      "title": "The KinematX Midcarpal Total Wrist Arthroplasty Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Scapholunate Advanced Collapse (SLAC)",
        "Scapholunate Crystalline Advanced Collapse (SCAC)",
        "Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC)",
        "Carpal Tunnel Syndrome (CTS)",
        "Kienbock's Disease of Adults",
        "Radial Malunion",
        "Ulnar Translocation",
        "Post Traumatic Arthritis",
        "Inflammatory Arthritis",
        "Osteoarthritis",
        "Scaphoid Non-union Advanced Collapse (SNAC)"
      ],
      "interventions": [
        {
          "name": "KinematX total wrist arthroplasty system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Extremity Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 50,
      "start_date": "2021-04-26",
      "completion_date": "2035-12",
      "has_results": false,
      "last_update_posted_date": "2023-11-15",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 4,
      "location_summary": "Loma Linda, California • Tampa, Florida • Indianapolis, Indiana + 1 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05719935"
    },
    {
      "nct_id": "NCT06257537",
      "title": "Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Osteo Arthritis Knee",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Device with 2.5% Diclofenac Patch",
          "type": "DEVICE"
        },
        {
          "name": "Sustained Acoustic Device with 0% Diclofenac Patch",
          "type": "DEVICE"
        },
        {
          "name": "2.5% Diclofenac Patches",
          "type": "DRUG"
        },
        {
          "name": "SAM Patch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 300,
      "start_date": "2024-10-01",
      "completion_date": "2026-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-03-06",
      "last_synced_at": "2026-06-11T06:28:25.815Z",
      "location_count": 3,
      "location_summary": "Stamford, Connecticut • Trumbull, Connecticut • Dryden, New York",
      "locations": [
        {
          "city": "Stamford",
          "state": "Connecticut"
        },
        {
          "city": "Trumbull",
          "state": "Connecticut"
        },
        {
          "city": "Dryden",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06257537"
    }
  ]
}