{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-invasive+Positive+Pressure+Ventilation",
    "query": {
      "condition": "Non-invasive Positive Pressure Ventilation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 28,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-invasive+Positive+Pressure+Ventilation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T18:26:28.164Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04169282",
      "title": "PEEP Mask for Tracheobronchomalacia-Induced Cough",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tracheobronchomalacia"
      ],
      "interventions": [
        {
          "name": "nPEP (non-invasive positive expiratory pressure) mask",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2021-08-30",
      "completion_date": "2022-08-15",
      "has_results": true,
      "last_update_posted_date": "2023-09-28",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04169282"
    },
    {
      "nct_id": "NCT07582211",
      "title": "Bilevel Positive Airway Pressure (BPAP) for Severe Asthma",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pediatric Asthma",
        "Acute Asthma",
        "BiPAP",
        "Non-invasive Positive Pressure Ventilation"
      ],
      "interventions": [
        {
          "name": "Bilevel positive airway pressure ventilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "5 Years to 17 Years"
      },
      "enrollment_count": 36,
      "start_date": "2026-06",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 3,
      "location_summary": "New York, New York • Columbus, Ohio • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07582211"
    },
    {
      "nct_id": "NCT04694638",
      "title": "Use of Combined Prone Positioning and High-Flow Nasal Cannula, and Non-invasive Positive Pressure Ventilation to Prevent Intubation in COVID-19 Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prone Positioning",
        "Covid19",
        "Hypoxemic Respiratory Failure",
        "ARDS",
        "Non Invasive Ventilation",
        "High Flow Nasal Cannulla"
      ],
      "interventions": [
        {
          "name": "Body position change",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 6,
      "start_date": "2020-05-21",
      "completion_date": "2023-05-10",
      "has_results": false,
      "last_update_posted_date": "2023-10-05",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04694638"
    },
    {
      "nct_id": "NCT01214200",
      "title": "High Intensity Non-Invasive Positive Pressure Ventilation (HINPPV)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease (COPD)"
      ],
      "interventions": [
        {
          "name": "Bilevel positive airway pressure (BiPAP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Philips Respironics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "Up to 80 Years"
      },
      "enrollment_count": 20,
      "start_date": "2010-08",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2019-01-02",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01214200"
    },
    {
      "nct_id": "NCT03882723",
      "title": "Noninvasive Ventilation Masks Carbon Dioxide Clearance in Normal Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "CO2 Clearance",
        "Mask Comfort",
        "Rebreathing Exhaled Gas"
      ],
      "interventions": [
        {
          "name": "Evaluated 4 masks used for NIV with mechanical ventilators",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2018-03-30",
      "completion_date": "2019-08-30",
      "has_results": true,
      "last_update_posted_date": "2023-06-28",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03882723"
    },
    {
      "nct_id": "NCT07558265",
      "title": "WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Hypoxic Respiratory Failure",
        "Acute Respiratory Distress Syndrome (ARDS)"
      ],
      "interventions": [
        {
          "name": "Non-Invasive Positive Pressure Ventilation",
          "type": "DEVICE"
        },
        {
          "name": "High Flow Nasal Oxygen",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2026-07",
      "completion_date": "2031-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 2,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07558265"
    },
    {
      "nct_id": "NCT03180385",
      "title": "NAVA Versus BiPAP Non-Invasive Respiratory Support in Infants Following Congenital Heart Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Neurally-Adusted Ventilatory Assist (NAVA)",
          "type": "DEVICE"
        },
        {
          "name": "Biphasic Positive Airway Pressure Support (BiPAP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospitals and Clinics of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "Up to 12 Months"
      },
      "enrollment_count": 15,
      "start_date": "2017-03-01",
      "completion_date": "2018-04-10",
      "has_results": true,
      "last_update_posted_date": "2020-03-10",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03180385"
    },
    {
      "nct_id": "NCT00871624",
      "title": "Efficacy and Safety of Dexmedetomidine During Non-Invasive Positive Pressure Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 36,
      "start_date": "2009-03",
      "completion_date": "2013-02",
      "has_results": true,
      "last_update_posted_date": "2017-12-18",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Winchester, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Winchester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00871624"
    },
    {
      "nct_id": "NCT00609882",
      "title": "Comparison of Humidified High Flow Nasal Cannula to Nasal CPAP in Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Insufficiency"
      ],
      "interventions": [
        {
          "name": "Nasal CPAP",
          "type": "OTHER"
        },
        {
          "name": "Humidified High Flow Nasal Cannula (HHFNC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Weeks",
        "sex": "ALL",
        "summary": "Up to 8 Weeks"
      },
      "enrollment_count": 420,
      "start_date": "2007-12",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2013-02-06",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 8,
      "location_summary": "Philadelphia, Pennsylvania • Lackland Air Force Base, Texas • Ogden, Utah + 3 more",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Lackland Air Force Base",
          "state": "Texas"
        },
        {
          "city": "Ogden",
          "state": "Utah"
        },
        {
          "city": "Provo",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00609882"
    },
    {
      "nct_id": "NCT03529461",
      "title": "Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Obesity",
        "Hypoxia"
      ],
      "interventions": [
        {
          "name": "Non-invasive positive pressure ventilation through nasal mask",
          "type": "DEVICE"
        },
        {
          "name": "Rescue non-invasive positive pressure ventilation through nasal mask",
          "type": "DEVICE"
        },
        {
          "name": "Secondary rescue maneuvers",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Bristol Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 56,
      "start_date": "2017-04-25",
      "completion_date": "2018-04-18",
      "has_results": true,
      "last_update_posted_date": "2019-05-31",
      "last_synced_at": "2026-06-10T18:26:28.164Z",
      "location_count": 1,
      "location_summary": "Bristol, Connecticut",
      "locations": [
        {
          "city": "Bristol",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03529461"
    }
  ]
}