{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-proliferative+Diabetic+Retinopathy&page=2", "query": { "condition": "Non-proliferative Diabetic Retinopathy", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Non-proliferative+Diabetic+Retinopathy&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-06-11T09:11:57.093Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04661358", "title": "Fenofibrate for Prevention of DR Worsening", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetic Retinopathy" ], "interventions": [ { "name": "Fenofibrate", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Jaeb Center for Health Research", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 560, "start_date": "2021-03-05", "completion_date": "2029-12", "has_results": false, "last_update_posted_date": "2025-11-13", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 66, "location_summary": "Glendale, California • Huntington Beach, California • Loma Linda, California + 55 more", "locations": [ { "city": "Glendale", "state": "California" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Loma Linda", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04661358" }, { "nct_id": "NCT04702048", "title": "Evaluation of the Retina in Patients With Non-proliferative Diabetic Retinopathy After Aflibercept Injection in the Eye", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Retinopathy, Diabetic" ], "interventions": [ { "name": "Aflibercept Injection", "type": "DRUG" }, { "name": "Sham injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2021-02-01", "completion_date": "2024-02-01", "has_results": false, "last_update_posted_date": "2021-05-05", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04702048" }, { "nct_id": "NCT04503551", "title": "A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema To Evaluate the Efficacy, Safety, and Pharmacokinetics of Ranibizumab Delivered Via the Port Delivery System Relative to the Comparator Arm", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetic Retinopathy" ], "interventions": [ { "name": "PDS Implant Pre-Filled with 100 mg/mL Ranibizumab", "type": "DRUG" }, { "name": "Intravitreal Ranibizumab 0.5 mg Injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 174, "start_date": "2020-08-10", "completion_date": "2026-02-23", "has_results": true, "last_update_posted_date": "2026-04-02", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 64, "location_summary": "Mesa, Arizona • Phoenix, Arizona • Bakersfield, California + 59 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "Encino", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04503551" }, { "nct_id": "NCT05383209", "title": "Study of EYP-1901 in Patients With Nonproliferative Diabetic Retinopathy (NPDR)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nonproliferative Diabetic Retinopathy" ], "interventions": [ { "name": "EYP-1901", "type": "DRUG" }, { "name": "Sham IVT", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "EyePoint Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 77, "start_date": "2022-09-28", "completion_date": "2024-05-06", "has_results": true, "last_update_posted_date": "2025-08-15", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 36, "location_summary": "Phoenix, Arizona • Huntington Beach, California • Oxnard, California + 33 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Oxnard", "state": "California" }, { "city": "Palm Desert", "state": "California" }, { "city": "Pasadena", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05383209" }, { "nct_id": "NCT06191094", "title": "Pre-operative Vabysmo in Patients With Non-clearing Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Diabetic Retinopathy", "Vitreous Hemorrhage Due to Diabetes Mellitus" ], "interventions": [ { "name": "Faricimab Injection", "type": "DRUG" }, { "name": "sham treatment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2024-07-12", "completion_date": "2028-01", "has_results": false, "last_update_posted_date": "2026-06-01", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT06191094" }, { "nct_id": "NCT00664183", "title": "A Safety and Efficacy Study of Vitreosolve® for Non-Proliferative Diabetic Retinopathy Subjects", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Diabetic Retinopathy" ], "interventions": [ { "name": "Vitreosolve", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vitreoretinal Technologies, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 400, "start_date": "2008-03", "completion_date": null, "has_results": false, "last_update_posted_date": "2009-10-20", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 10, "location_summary": "Phoenix, Arizona • Beverly Hills, California • Santa Ana, California + 7 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Santa Ana", "state": "California" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Lakeland", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00664183" }, { "nct_id": "NCT05066230", "title": "A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Non-proliferative Diabetic Retinopathy (NPDR)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Non-proliferative Diabetic Retinopathy" ], "interventions": [ { "name": "KSI-301", "type": "DRUG" }, { "name": "Sham injection", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Kodiak Sciences Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 253, "start_date": "2021-09-07", "completion_date": "2023-08-31", "has_results": true, "last_update_posted_date": "2024-09-05", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 46, "location_summary": "Phoenix, Arizona • Beverly Hills, California • Fullerton, California + 42 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Fullerton", "state": "California" }, { "city": "Redlands", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05066230" }, { "nct_id": "NCT01625598", "title": "Computer Detection of Diabetic Retinopathy Compared to Clinical Examination", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Diabetic Retinopathy" ], "interventions": [ { "name": "Photography of the retina", "type": "PROCEDURE" }, { "name": "Retinal photography", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Digital Diagnostics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 600, "start_date": "2012-04", "completion_date": "2014-04", "has_results": false, "last_update_posted_date": "2014-04-22", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 7, "location_summary": "Mesa, Arizona • Phoenix, Arizona • Cedar Rapids, Iowa + 2 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Cedar Rapids", "state": "Iowa" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01625598" }, { "nct_id": "NCT01880372", "title": "The Use of Alpha Lipoic Acid for the Treatment and Prevention of Diabetic Retinopathy", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Moderate Non-proliferative Diabetic Retinopathy" ], "interventions": [ { "name": "Alpha Lipoic Acid", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Ferris State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1, "start_date": "2013-09", "completion_date": "2016-04", "has_results": false, "last_update_posted_date": "2019-02-15", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 2, "location_summary": "Big Rapids, Michigan • Grand Rapids, Michigan", "locations": [ { "city": "Big Rapids", "state": "Michigan" }, { "city": "Grand Rapids", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01880372" }, { "nct_id": "NCT07592273", "title": "Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Diabetic Retinopathy" ], "interventions": [ { "name": "Surabgene Lomparvovec", "type": "DRUG" }, { "name": "Sham", "type": "DRUG" }, { "name": "Topical Steroid", "type": "DRUG" }, { "name": "Artificial Tears", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 576, "start_date": "2026-05-20", "completion_date": "2036-01", "has_results": false, "last_update_posted_date": "2026-06-04", "last_synced_at": "2026-06-11T09:11:57.093Z", "location_count": 3, "location_summary": "Mountain View, California • Oak Forest, Illinois • Austin, Texas", "locations": [ { "city": "Mountain View", "state": "California" }, { "city": "Oak Forest", "state": "Illinois" }, { "city": "Austin", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07592273" } ] }