{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Noninvasive+Prenatal+Screening",
    "query": {
      "condition": "Noninvasive Prenatal Screening"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Noninvasive+Prenatal+Screening&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T01:53:51.782Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02226315",
      "title": "Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Down Syndrome",
        "Edwards Syndrome",
        "Patau Syndrome",
        "Turner Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Sequenom, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2014-08",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2015-09-17",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02226315"
    },
    {
      "nct_id": "NCT07557303",
      "title": "Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delivery of Health Care",
        "Genetic Testing",
        "Humans",
        "Pregnancy",
        "Noninvasive Prenatal Testing",
        "Informed Consent",
        "Internet-Based Intervention",
        "Self Efficacy",
        "Pregnant People",
        "Decision Making",
        "Health Education",
        "Patient Education as Topic/Method"
      ],
      "interventions": [
        {
          "name": "Mobile-based Educational Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 1400,
      "start_date": "2026-08-01",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Jacksonville, Florida • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07557303"
    },
    {
      "nct_id": "NCT04488393",
      "title": "Clinical Performance of NIPT in Multiple Gestation Pregnancies",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Trisomy 21 in Fetus"
      ],
      "interventions": [
        {
          "name": "MaterniT21 PLUS and GENOME Laboratory-Developed Tests",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 2000,
      "start_date": "2020-03-01",
      "completion_date": "2022-06-19",
      "has_results": false,
      "last_update_posted_date": "2022-12-07",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04488393"
    },
    {
      "nct_id": "NCT00064597",
      "title": "Noninvasive Prenatal Diagnosis: Using Fetal Cells From Maternal Blood",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chromosome Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 45 Years · Female only"
      },
      "enrollment_count": 3500,
      "start_date": "1987-12",
      "completion_date": "2003-12",
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 5,
      "location_summary": "Chicago, Illinois • Boston, Massachusetts • Detroit, Michigan + 2 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00064597"
    },
    {
      "nct_id": "NCT01052688",
      "title": "Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Down Syndrome",
        "Aneuploidy"
      ],
      "interventions": [
        {
          "name": "Maternal blood draw of 30 to 50ml",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Sequenom, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 150,
      "start_date": "2009-11",
      "completion_date": "2021-08-31",
      "has_results": false,
      "last_update_posted_date": "2021-09-20",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 10,
      "location_summary": "Phoenix, Arizona • San Diego, California • Washington D.C., District of Columbia + 3 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01052688"
    },
    {
      "nct_id": "NCT05076734",
      "title": "Cell- Based Noninvasive Prenatal Testing (NIPT): Single Cell Prenatal Diagnosis (SCPD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy Related"
      ],
      "interventions": [
        {
          "name": "Redraw for analysis of blood samples from healthy pregnant women",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Luna Genetics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 157,
      "start_date": "2020-06-12",
      "completion_date": "2021-12-30",
      "has_results": false,
      "last_update_posted_date": "2023-03-24",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05076734"
    },
    {
      "nct_id": "NCT03420274",
      "title": "Ensuring Patients' Informed Access to Noninvasive Prenatal Testing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Genetic Disease",
        "Genetic Syndrome",
        "Prenatal Disorder",
        "Prenatal Maternal Abnormality",
        "Pregnancy Complications"
      ],
      "interventions": [
        {
          "name": "NEST",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 691,
      "start_date": "2018-02-19",
      "completion_date": "2023-06-15",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 2,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03420274"
    },
    {
      "nct_id": "NCT02284399",
      "title": "National Prevalence and Impact of Noninvasive Prenatal Testing",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aneuploidy"
      ],
      "interventions": [
        {
          "name": "non-invasive prenatal testing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Obstetrix Medical Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 4488,
      "start_date": "2014-01",
      "completion_date": "2016-12-01",
      "has_results": true,
      "last_update_posted_date": "2019-06-19",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 7,
      "location_summary": "Phoenix, Arizona • Long Beach, California • San Jose, California + 4 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02284399"
    },
    {
      "nct_id": "NCT04285814",
      "title": "Technology Development for Noninvasive Prenatal Genetic Diagnosis Using Whole Fetal Cells From Maternal Peripheral Blood",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Copy Number Abnormality",
        "Prenatal Diagnosis",
        "Genetic Disease"
      ],
      "interventions": [
        {
          "name": "Whole Fetal Cell (WFC) Testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 33,
      "start_date": "2020-09-01",
      "completion_date": "2023-07-20",
      "has_results": false,
      "last_update_posted_date": "2025-01-29",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 2,
      "location_summary": "New York, New York • Houston, Texas",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04285814"
    },
    {
      "nct_id": "NCT01597063",
      "title": "Clinical Evaluation of the SEQureDx Trisomy Test in Low Risk Pregnancies",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aneuploidy",
        "Down Syndrome",
        "Noninvasive Prenatal Screening"
      ],
      "interventions": [
        {
          "name": "SEQureDx Trisomy Test",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sequenom, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "34 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 34 Years · Female only"
      },
      "enrollment_count": 3333,
      "start_date": "2012-07",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2016-04-20",
      "last_synced_at": "2026-07-23T01:53:51.782Z",
      "location_count": 27,
      "location_summary": "Mobile, Alabama • Chandler, Arizona • Phoenix, Arizona + 22 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Glendale",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01597063"
    }
  ]
}