{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Normal+Cognition", "query": { "condition": "Normal Cognition" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 156, "total_pages": 16, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Normal+Cognition&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-05-22T05:46:30.956Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04635657", "title": "Cognitive Status After Removal of Skull Base Meningioma", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Meningioma", "Skull Base Meningioma", "Frontal Meningioma", "Temporal Meningioma", "Cognitive Impairment", "Cognitive Decline", "Post-Surgical Cognition" ], "interventions": [ { "name": "Long-term Cognitive testing", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Ohio State University", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": "89 Years", "sex": "ALL", "summary": "18 Years to 89 Years" }, "enrollment_count": 50, "start_date": "2019-12-10", "completion_date": "2024-12-31", "has_results": false, "last_update_posted_date": "2023-10-24", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04635657" }, { "nct_id": "NCT06539169", "title": "FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Alpha-Thalassemia", "Beta-Thalassemia", "Amyloidosis", "Amyotrophic Lateral Sclerosis", "Creutzfeld-Jakob Disease", "Cystic Fibrosis", "Duchenne Muscular Dystrophy", "Early-Onset Alzheimer Disease", "Ehlers-Danlos Syndrome", "Huntington Disease", "Gaucher Disease", "GM1 Gangliosidosis", "Myasthenia Gravis", "Pompe Disease", "Sickle Cell Disease", "Transthyretin Amyloid Cardiomyopathy", "Rare Diseases" ], "interventions": [], "intervention_types": [], "sponsor": "xCures", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1000, "start_date": "2024-06-10", "completion_date": "2026-06-10", "has_results": false, "last_update_posted_date": "2024-11-14", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 1, "location_summary": "Los Altos, California", "locations": [ { "city": "Los Altos", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06539169" }, { "nct_id": "NCT06580002", "title": "Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Breast Cancer", "Sarcoma", "Gastric Cancer", "Lung Cancer", "Head and Neck Cancer", "Colorectal Cancer", "Ovarian Cancer", "Liver Cancer", "Genitourinary Cancer", "Gynecologic Cancer" ], "interventions": [ { "name": "Riluzole", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Irvine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 51, "start_date": "2024-12-02", "completion_date": "2027-12", "has_results": false, "last_update_posted_date": "2025-06-26", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 1, "location_summary": "Orange, California", "locations": [ { "city": "Orange", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06580002" }, { "nct_id": "NCT02662335", "title": "Computerized Cognitive Retraining in Improving Cognitive Function in Breast Cancer Survivors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cancer Survivor", "Stage 0 Breast Cancer", "Stage IA Breast Cancer", "Stage IB Breast Cancer", "Stage IIA Breast Cancer", "Stage IIB Breast Cancer", "Stage IIIA Breast Cancer", "Stage IIIB Breast Cancer", "Stage IIIC Breast Cancer" ], "interventions": [ { "name": "Computer-Assisted Cognitive Training", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Standard Follow-Up Care", "type": "PROCEDURE" } ], "intervention_types": [ "OTHER", "PROCEDURE" ], "sponsor": "Fred Hutchinson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2016-05", "completion_date": "2017-11-30", "has_results": false, "last_update_posted_date": "2017-12-13", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT02662335" }, { "nct_id": "NCT00681928", "title": "Cognitive Function in Older Women With Stage I, Stage II, or Stage III Breast Cancer Receiving Hormone Therapy", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Breast Cancer" ], "interventions": [ { "name": "anastrozole", "type": "DRUG" }, { "name": "letrozole", "type": "DRUG" }, { "name": "questionnaire administration", "type": "OTHER" }, { "name": "cognitive assessment", "type": "PROCEDURE" }, { "name": "psychosocial assessment and care", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "OTHER", "PROCEDURE" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "FEMALE", "summary": "65 Years and older · Female only" }, "enrollment_count": 72, "start_date": "2007-10", "completion_date": "2011-01", "has_results": false, "last_update_posted_date": "2011-12-02", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 1, "location_summary": "Duarte, California", "locations": [ { "city": "Duarte", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00681928" }, { "nct_id": "NCT03143894", "title": "Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Breast Cancer", "Cognitive Dysfunction", "Fatigue" ], "interventions": [ { "name": "tDCS", "type": "DEVICE" }, { "name": "Sham tDCS", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 7, "start_date": "2017-04-21", "completion_date": "2020-06-24", "has_results": true, "last_update_posted_date": "2021-05-12", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 3, "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland • Lutherville, Maryland", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Lutherville", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03143894" }, { "nct_id": "NCT02947022", "title": "Effects of IV-Administered Ca-DTPA and Zn-DTPA To Treat Patients With Gadolinium Deposition Disease", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Headache", "Cognitive Disturbance", "Skin Hyperpigmentation", "Arthralgia" ], "interventions": [ { "name": "Calcium DTPA", "type": "DRUG" }, { "name": "Zinc DTPA", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 1, "start_date": "2016-10", "completion_date": "2017-01-31", "has_results": true, "last_update_posted_date": "2018-04-06", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02947022" }, { "nct_id": "NCT07415707", "title": "The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Aging", "Alcohol Drinking" ], "interventions": [ { "name": "Visbiome", "type": "DIETARY_SUPPLEMENT" }, { "name": "Motivational Interviewing", "type": "BEHAVIORAL" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "BEHAVIORAL", "OTHER" ], "sponsor": "University of Miami", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "65 Years", "maximum_age": "84 Years", "sex": "ALL", "summary": "65 Years to 84 Years" }, "enrollment_count": 20, "start_date": "2026-02-26", "completion_date": "2027-04-30", "has_results": false, "last_update_posted_date": "2026-03-04", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07415707" }, { "nct_id": "NCT04421014", "title": "Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults 55 Years Old or Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Metabolic Syndrome", "Normal Cognition" ], "interventions": [ { "name": "Ketone Ester drink", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo: isocaloric dextrose drink", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "National Institute on Aging (NIA)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": null, "sex": "ALL", "summary": "55 Years and older" }, "enrollment_count": 99, "start_date": "2021-06-24", "completion_date": "2025-06-02", "has_results": true, "last_update_posted_date": "2026-04-02", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04421014" }, { "nct_id": "NCT02515487", "title": "An Investigation of Chemotherapy Induced Cognitive Impairments in Breast Cancer Survivors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Breast Cancer" ], "interventions": [ { "name": "Brain Fitness Program (BFP)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "FEMALE", "summary": "18 Years to 70 Years · Female only" }, "enrollment_count": 11, "start_date": "2013-09", "completion_date": "2018-01", "has_results": false, "last_update_posted_date": "2018-02-06", "last_synced_at": "2026-05-22T05:46:30.956Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02515487" } ] }