{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Normal+Cognition&page=6",
    "query": {
      "condition": "Normal Cognition",
      "page": 6
    },
    "page_size": 10
  },
  "pagination": {
    "page": 6,
    "page_size": 10,
    "total_count": 159,
    "total_pages": 16,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Normal+Cognition&page=7&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Normal+Cognition&page=5&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T08:55:08.962Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01870375",
      "title": "Longitudinal Studies of Brain Structure and Function in MPS Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mucopolysaccharidosis Type I",
        "Mucopolysaccharidosis Type II",
        "Mucopolysaccharidosis Type VI",
        "Mucopolysaccharidosis Type IV",
        "Mucopolysaccharidosis Type VII"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2009-09",
      "completion_date": "2019-08-31",
      "has_results": false,
      "last_update_posted_date": "2019-09-06",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 3,
      "location_summary": "Oakland, California • Minneapolis, Minnesota • New York, New York",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01870375"
    },
    {
      "nct_id": "NCT02822573",
      "title": "Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cognitive Dysfunction",
        "Memory Impairment"
      ],
      "interventions": [
        {
          "name": "Donepezil 5 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 276,
      "start_date": "2017-05-30",
      "completion_date": "2022-07-29",
      "has_results": true,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 278,
      "location_summary": "Anaheim, California • Antioch, California • Baldwin Park, California + 206 more",
      "locations": [
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Antioch",
          "state": "California"
        },
        {
          "city": "Baldwin Park",
          "state": "California"
        },
        {
          "city": "Bellflower",
          "state": "California"
        },
        {
          "city": "Fontana",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02822573"
    },
    {
      "nct_id": "NCT04848675",
      "title": "Novel Time-efficient Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blood Pressure",
        "Endothelial Dysfunction",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Inspiratory muscle strength training",
          "type": "OTHER"
        },
        {
          "name": "Brisk walking",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Boulder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 102,
      "start_date": "2021-05-07",
      "completion_date": "2025-05-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-02",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 1,
      "location_summary": "Boulder, Colorado",
      "locations": [
        {
          "city": "Boulder",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04848675"
    },
    {
      "nct_id": "NCT02290834",
      "title": "Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Impaired Cognition",
        "Chemo-brain",
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Cognitive, functional and subjective assessments",
          "type": "OTHER"
        },
        {
          "name": "MRI",
          "type": "DEVICE"
        },
        {
          "name": "PET Scan",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE",
        "RADIATION"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "60 Years and older · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2015-03",
      "completion_date": "2028-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Salem, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Salem",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02290834"
    },
    {
      "nct_id": "NCT03224988",
      "title": "Bilateral Brain Dynamics in Cognition and Aging",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Aging",
        "MCI"
      ],
      "interventions": [
        {
          "name": "TMS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "60 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2018-03-20",
      "completion_date": "2022-01-20",
      "has_results": false,
      "last_update_posted_date": "2022-03-03",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03224988"
    },
    {
      "nct_id": "NCT00911690",
      "title": "Establishment of a Bank of Biospecimens for Future Research on Age-related Cognitive Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dementia",
        "Alzheimers Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Corewell Health East",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "60 Years to 90 Years"
      },
      "enrollment_count": 102,
      "start_date": "2009-07",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2016-11-04",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 1,
      "location_summary": "Royal Oak, Michigan",
      "locations": [
        {
          "city": "Royal Oak",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00911690"
    },
    {
      "nct_id": "NCT00387062",
      "title": "Computer-Based Training in Patients With Post-Chemotherapy Cognitive Impairment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Breast Cancer",
        "Cognitive Symptoms",
        "Memory Disorders"
      ],
      "interventions": [
        {
          "name": "Computer-based Cognitive Training",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Posit Science Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2006-10",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2008-06-24",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00387062"
    },
    {
      "nct_id": "NCT03233646",
      "title": "Retinal Imaging in Neurodegenerative Disease",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer's Disease",
        "Mild Cognitive Impairment",
        "Parkinson's Disease",
        "Multiple Sclerosis",
        "Huntington Disease",
        "Lewy Body Dementia",
        "Frontotemporal Dementia",
        "Amyotrophic Lateral Sclerosis (ALS)",
        "APOE-4 Positive",
        "Traumatic Brain Injury",
        "Concussion",
        "Post-Traumatic Stress Disorder",
        "Down Syndrome",
        "Neuro-Degenerative Disease",
        "Normal Cognition"
      ],
      "interventions": [
        {
          "name": "Retinal and Choroidal Imaging",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2017-07-20",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03233646"
    },
    {
      "nct_id": "NCT01205503",
      "title": "Trial of Mesna to Prevent Doxorubicin-induced Plasma Protein Oxidation and Tumor Necrosis Factor Alpha (TNF-α) Release",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer",
        "Non-Hodgkin's Lymphoma"
      ],
      "interventions": [
        {
          "name": "Mesna",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        },
        {
          "name": "Doxorubicin",
          "type": "DRUG"
        },
        {
          "name": "Cyclophosphamide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mara Chambers",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2010-09",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2016-02-24",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01205503"
    },
    {
      "nct_id": "NCT00977418",
      "title": "Brain and Cognitive Changes After Reasoning or Physical Training in Cognitively Normal Seniors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hearing Impaired"
      ],
      "interventions": [
        {
          "name": "SMART- Strategic Memory and Reasoning Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physical Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "The University of Texas at Dallas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "60 Years to 75 Years"
      },
      "enrollment_count": 60,
      "start_date": "2012-06",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2016-07-11",
      "last_synced_at": "2026-10-22T08:55:08.962Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00977418"
    }
  ]
}