{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Normal+and+Impaired+Renal+Function&page=2", "query": { "condition": "Normal and Impaired Renal Function", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Normal+and+Impaired+Renal+Function&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-26T19:05:03.280Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04699032", "title": "Study of Pharmacokinetics and Safety of Apraglutide in Participants With Normal and Impaired Kidney Function.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Chronic Kidney Disease" ], "interventions": [ { "name": "Apraglutide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VectivBio AG", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 16, "start_date": "2020-12-08", "completion_date": "2021-07-05", "has_results": true, "last_update_posted_date": "2024-10-26", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 2, "location_summary": "Orlando, Florida • Saint Paul, Minnesota", "locations": [ { "city": "Orlando", "state": "Florida" }, { "city": "Saint Paul", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT04699032" }, { "nct_id": "NCT05489614", "title": "A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Normal Renal Function and Participants With Various Degrees of Renal Impairment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Renal Impairment" ], "interventions": [ { "name": "Olpasiran", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 33, "start_date": "2022-09-13", "completion_date": "2023-12-19", "has_results": false, "last_update_posted_date": "2025-11-26", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 6, "location_summary": "Rialto, California • Yucaipa, California • Miami, Florida + 2 more", "locations": [ { "city": "Rialto", "state": "California" }, { "city": "Yucaipa", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05489614" }, { "nct_id": "NCT02879812", "title": "Disparities in National Kidney Allocation Policy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Kidney Disorders" ], "interventions": [ { "name": "Performance Feedback Reports", "type": "OTHER" }, { "name": "Educational Video for Staff", "type": "OTHER" }, { "name": "Educational Video for Patients", "type": "OTHER" }, { "name": "Educational Webinar", "type": "OTHER" }, { "name": "Standard Care", "type": "OTHER" }, { "name": "United Network for Organ Sharing (UNOS) Pamphlet", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 56332, "start_date": "2016-09", "completion_date": "2019-08-02", "has_results": true, "last_update_posted_date": "2025-10-07", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 3, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02879812" }, { "nct_id": "NCT05940402", "title": "A Study to Evaluate Pharmacokinetic and Safety Trial of Emraclidine in Participants With Renal Impairment Compared With Participants With Normal Renal Function", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Renal Impairment" ], "interventions": [ { "name": "Emraclidine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 58, "start_date": "2023-07-24", "completion_date": "2024-12-19", "has_results": false, "last_update_posted_date": "2025-04-04", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 5, "location_summary": "Tustin, California • Miami, Florida • Orlando, Florida + 1 more", "locations": [ { "city": "Tustin", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT05940402" }, { "nct_id": "NCT07032272", "title": "A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Severe Renal Impairment Compared to Matched Healthy Participants.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Autoimmune and Chronic Inflammatory Diseases" ], "interventions": [ { "name": "remibrutinib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 16, "start_date": "2025-07-23", "completion_date": "2025-10-14", "has_results": false, "last_update_posted_date": "2026-09-17", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 4, "location_summary": "Miami, Florida • Miami Lakes, Florida • Orlando, Florida + 1 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Miami Lakes", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07032272" }, { "nct_id": "NCT01931644", "title": "At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "All Diagnosed Health Conditions", "ADD/ADHD", "Alopecia Areata", "Ankylosing Spondylitis", "Asthma", "Atopic Dermatitis Eczema", "Beta Thalassemia", "Bipolar Disorder", "Breast Cancer", "Celiac Disease", "Cervical Cancer", "Chronic Inflammatory Demyelinating Polyneuropathy", "Chronic Kidney Diseases", "Chronic Obstructive Pulmonary Disease", "Colon Cancer", "Colorectal Cancer", "Crohn's Disease", "Cystic Fibrosis", "Depression", "Diabetes Mellitus", "Duchenne Muscular Dystrophy", "Endometriosis", "Epilepsy", "Facioscapulohumeral Muscular Dystrophy", "G6PD Deficiency", "General Anxiety Disorder", "Hepatitis B", "Hereditary Hemorrhagic Telangiectasia", "HIV/AIDS", "Human Papilloma Virus", "Huntington's Disease", "Idiopathic Thrombocytopenic Purpura", "Insomnia", "Kidney Cancer", "Leukemia", "Lung Cancer", "Lupus Nephritis", "Lymphoma", "Melanoma", "Multiple Myeloma", "Multiple Sclerosis", "Myositis", "Myotonic Dystrophy", "Ovarian Cancer", "Pancreatic Cancer", "Parkinson's Disease", "Polycystic Kidney Diseases", "Prostate Cancer", "Psoriasis", "Psoriatic Arthritis", "Rosacea", "Scleroderma", "Sickle Cell Anemia", "Sickle Cell Trait", "Sjogren's Syndrome", "Skin Cancer", "Spinal Muscular Atrophy", "Systemic Lupus Erythematosus", "Thrombotic Thrombocytopenic Purpura", "Trisomy 21", "Ulcerative Colitis" ], "interventions": [], "intervention_types": [], "sponsor": "Sanguine Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 17667, "start_date": "2013-07", "completion_date": "2024-04", "has_results": false, "last_update_posted_date": "2024-04-18", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01931644" }, { "nct_id": "NCT01120314", "title": "Pharmacokinetic, Pharmacodynamic and Tolerability Study of Otamixaban in Patients With Mild, Moderate and Severe Renal Impairment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Renal Impairment" ], "interventions": [ { "name": "OTAMIXABAN (XRP0673)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "18 Years to 79 Years" }, "enrollment_count": 48, "start_date": "2010-04", "completion_date": "2011-07", "has_results": false, "last_update_posted_date": "2014-05-12", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 4, "location_summary": "Miami Gardens, Florida • Orlando, Florida • Saint Paul, Minnesota + 1 more", "locations": [ { "city": "Miami Gardens", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Saint Paul", "state": "Minnesota" }, { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01120314" }, { "nct_id": "NCT03636269", "title": "CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Uremic Pruritus" ], "interventions": [ { "name": "CR845 0.5 mcg/kg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cara Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 473, "start_date": "2018-07-17", "completion_date": "2020-03-30", "has_results": true, "last_update_posted_date": "2022-04-26", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 29, "location_summary": "Chula Vista, California • Fountain Valley, California • Northridge, California + 25 more", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Northridge", "state": "California" }, { "city": "Riverside", "state": "California" }, { "city": "San Dimas", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03636269" }, { "nct_id": "NCT02852239", "title": "Pharmacokinetics of Dabrafenib in Subjects With Renal Impairment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Renal Impairment" ], "interventions": [ { "name": "dabrafenib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 22, "start_date": "2016-12-19", "completion_date": "2019-09-27", "has_results": false, "last_update_posted_date": "2020-12-09", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 3, "location_summary": "DeBary, Florida • Berlin, New Jersey • Raleigh, North Carolina", "locations": [ { "city": "DeBary", "state": "Florida" }, { "city": "Berlin", "state": "New Jersey" }, { "city": "Raleigh", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02852239" }, { "nct_id": "NCT05936138", "title": "A Phase 1, Parallel, Single-Dose, Open-Label, Single-Period Study of LY3502970 in Participants With Normal Renal Function and Participants With Renal Impairment.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Renal Insufficiency", "Healthy" ], "interventions": [ { "name": "LY3502970", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 24, "start_date": "2023-07-13", "completion_date": "2024-04-11", "has_results": true, "last_update_posted_date": "2026-06-09", "last_synced_at": "2026-09-26T19:05:03.280Z", "location_count": 4, "location_summary": "Miami, Florida • Orlando, Florida • Knoxville, Tennessee", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT05936138" } ] }