{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Norovirus+Infections",
    "query": {
      "condition": "Norovirus Infections"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Norovirus+Infections&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:53:06.039Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01609257",
      "title": "Norovirus Bivalent-Vaccine Efficacy Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Prevention From Norovirus Infection"
      ],
      "interventions": [
        {
          "name": "Norovirus Bivalent Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Saline Comparator",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Takeda",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 132,
      "start_date": "2012-07-16",
      "completion_date": "2014-03-18",
      "has_results": true,
      "last_update_posted_date": "2019-01-09",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 5,
      "location_summary": "Atlanta, Georgia • Baltimore, Maryland • Rochester, New York + 2 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01609257"
    },
    {
      "nct_id": "NCT04691622",
      "title": "Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Viral Infection",
        "Hematopoietic Stem Cell Transplantation (HSCT)",
        "Primary Immunodeficiency Disorders (PID)"
      ],
      "interventions": [
        {
          "name": "Norovirus -specific T-cell (NST) therapy",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "3 Months to 80 Years"
      },
      "enrollment_count": 48,
      "start_date": "2022-03-17",
      "completion_date": "2028-10-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-26",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 3,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland • Bethesda, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04691622"
    },
    {
      "nct_id": "NCT02371538",
      "title": "Human Breastmilk in Young Children With Norovirus Infection of the Gut",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Norovirus Infections"
      ],
      "interventions": [
        {
          "name": "Donor Breastmilk",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 4,
      "start_date": "2014-10",
      "completion_date": "2016-07-02",
      "has_results": false,
      "last_update_posted_date": "2020-08-20",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02371538"
    },
    {
      "nct_id": "NCT04854746",
      "title": "Ph 1b: Safety & Immunogenicity of Ad5 Based Oral Norovirus Vaccine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Norovirus Infections"
      ],
      "interventions": [
        {
          "name": "VXA-GI.1.NN",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo Tablet",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Vaxart",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "55 Years to 80 Years"
      },
      "enrollment_count": 66,
      "start_date": "2021-04-26",
      "completion_date": "2022-01-04",
      "has_results": false,
      "last_update_posted_date": "2023-02-13",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 3,
      "location_summary": "Cypress, California • New Orleans, Louisiana • Austin, Texas",
      "locations": [
        {
          "city": "Cypress",
          "state": "California"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04854746"
    },
    {
      "nct_id": "NCT06944717",
      "title": "A Trial of a Norovirus G1.1 and G2.4 Vaccine Administered Orally to Healthy Participants Aged ≥ 18 Years and ≤ 80 Years Old",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Norovirus Infections"
      ],
      "interventions": [
        {
          "name": "VXA-G1.1-NN",
          "type": "BIOLOGICAL"
        },
        {
          "name": "VXA-G2.4-NS",
          "type": "BIOLOGICAL"
        },
        {
          "name": "VXA G1.1 NN-T",
          "type": "BIOLOGICAL"
        },
        {
          "name": "VXA G2.4 NS-T",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Vaxart",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-03-03",
      "completion_date": "2026-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-29",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 1,
      "location_summary": "Lenexa, Kansas",
      "locations": [
        {
          "city": "Lenexa",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06944717"
    },
    {
      "nct_id": "NCT03897309",
      "title": "Safety & Immunogenicity Study of Ad5 Based Oral Norovirus Vaccines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Norovirus Infection"
      ],
      "interventions": [
        {
          "name": "VXA-G1.1-NN",
          "type": "BIOLOGICAL"
        },
        {
          "name": "VXA-G2.4-NS",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo Tablets",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Vaxart",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 86,
      "start_date": "2019-03-20",
      "completion_date": "2021-04-01",
      "has_results": false,
      "last_update_posted_date": "2022-09-21",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03897309"
    },
    {
      "nct_id": "NCT04875676",
      "title": "Immunogenicity & Safety Study of Adenovirus Type 5 (AD5) Based Oral Norovirus Vaccines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Norovirus Infections"
      ],
      "interventions": [
        {
          "name": "VXA-G1.1-NN",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Vaxart",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 30,
      "start_date": "2021-04-30",
      "completion_date": "2022-02-16",
      "has_results": true,
      "last_update_posted_date": "2024-05-22",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 1,
      "location_summary": "Cypress, California",
      "locations": [
        {
          "city": "Cypress",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04875676"
    },
    {
      "nct_id": "NCT01435811",
      "title": "Dose Range Evaluation of Norovirus Challenge Pool (GII.4, CIN-1)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Norovirus Infections"
      ],
      "interventions": [
        {
          "name": "Norovirus challenge pool (GII.4, CIN-1)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 60,
      "start_date": "2011-08",
      "completion_date": "2012-11",
      "has_results": false,
      "last_update_posted_date": "2014-05-07",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01435811"
    },
    {
      "nct_id": "NCT05212168",
      "title": "Norovirus Challenge Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Norovirus Infections"
      ],
      "interventions": [
        {
          "name": "VXA-G1.1-NN",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo Tablets",
          "type": "OTHER"
        },
        {
          "name": "Norovirus GI.1 Norwalk Virus Inoculum",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Vaxart",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 165,
      "start_date": "2021-12-27",
      "completion_date": "2023-10-27",
      "has_results": true,
      "last_update_posted_date": "2025-11-05",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 1,
      "location_summary": "Cypress, California",
      "locations": [
        {
          "city": "Cypress",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05212168"
    },
    {
      "nct_id": "NCT05626803",
      "title": "A Study to Determine the Safety and Immunogenicity of Bivalent GI.1 and GII.4 Vaccines in Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Norovirus Infections"
      ],
      "interventions": [
        {
          "name": "Open label Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose",
          "type": "DRUG"
        },
        {
          "name": "Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose",
          "type": "DRUG"
        },
        {
          "name": "Bivalent GII.4/GI.1 medium dose vaccine 1×10 to the power 11 IU/dose",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vaxart",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 135,
      "start_date": "2023-01-26",
      "completion_date": "2023-10-16",
      "has_results": true,
      "last_update_posted_date": "2025-04-15",
      "last_synced_at": "2026-06-11T04:53:06.039Z",
      "location_count": 3,
      "location_summary": "Long Beach, California • Lenexa, Kansas • Saint Paul, Minnesota",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Lenexa",
          "state": "Kansas"
        },
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05626803"
    }
  ]
}