{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=OSA+COPD+Overlap+Syndrome",
    "query": {
      "condition": "OSA COPD Overlap Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T03:23:19.888Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01033266",
      "title": "Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "CPET",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2009-02-01",
      "completion_date": "2014-02-28",
      "has_results": false,
      "last_update_posted_date": "2020-04-14",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 2,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01033266"
    },
    {
      "nct_id": "NCT02567448",
      "title": "Pathophysiology of the Upper Airway in Patients With COPD and Concomitant OSA",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Sleep and pulmonary physiologic measurements",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2015-07-01",
      "completion_date": "2016-08-11",
      "has_results": false,
      "last_update_posted_date": "2020-05-07",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02567448"
    },
    {
      "nct_id": "NCT01261377",
      "title": "Cardiac Hemodynamics in Overlap Syndrome (COPD With Obstructive Sleep Apnea)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chronic Obstructive Airway Disease"
      ],
      "interventions": [
        {
          "name": "Bi-level positive airway pressure (BPAP)",
          "type": "DEVICE"
        },
        {
          "name": "Oxygen",
          "type": "DRUG"
        },
        {
          "name": "CPAP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 0,
      "start_date": "2010-11",
      "completion_date": "2011-09",
      "has_results": false,
      "last_update_posted_date": "2017-01-12",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01261377"
    },
    {
      "nct_id": "NCT03446768",
      "title": "Monitoring and Peer Support to Improve Treatment Adherence and Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease",
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Peer support",
          "type": "OTHER"
        },
        {
          "name": "Online platform",
          "type": "OTHER"
        },
        {
          "name": "Respiratory Therapist support",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "COPD Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 294,
      "start_date": "2018-02-01",
      "completion_date": "2019-10-31",
      "has_results": true,
      "last_update_posted_date": "2021-12-03",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03446768"
    },
    {
      "nct_id": "NCT05254431",
      "title": "The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COPD",
        "OSA"
      ],
      "interventions": [
        {
          "name": "Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 28,
      "start_date": "2022-04-01",
      "completion_date": "2027-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 1,
      "location_summary": "Salem, Virginia",
      "locations": [
        {
          "city": "Salem",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05254431"
    },
    {
      "nct_id": "NCT04179981",
      "title": "Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Apnea Syndrome",
        "Obstructive Sleep Apnea",
        "COPD",
        "Overlap Syndrome",
        "Quality of Life",
        "Neurocognitive Function",
        "Sleepiness",
        "Elderly",
        "Positive Airway Pressure"
      ],
      "interventions": [
        {
          "name": "Positive airway pressure",
          "type": "DEVICE"
        },
        {
          "name": "Conservative care (control arm)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 668,
      "start_date": "2020-12-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04179981"
    },
    {
      "nct_id": "NCT01427673",
      "title": "Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease",
        "Obstructive Sleep Apnea",
        "Overlap Syndrome"
      ],
      "interventions": [
        {
          "name": "Bipap procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "United States Air Force",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "35 Years to 80 Years"
      },
      "enrollment_count": 150,
      "start_date": "2011-12",
      "completion_date": "2014-02",
      "has_results": false,
      "last_update_posted_date": "2011-09-01",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 1,
      "location_summary": "Wpafb, Ohio",
      "locations": [
        {
          "city": "Wpafb",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01427673"
    },
    {
      "nct_id": "NCT02703207",
      "title": "Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "OSA COPD Overlap Syndrome"
      ],
      "interventions": [
        {
          "name": "Positive airway pressure",
          "type": "DEVICE"
        },
        {
          "name": "NIPPV and /or oxygen",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "60 Years to 89 Years"
      },
      "enrollment_count": 108,
      "start_date": "2016-08-17",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-26",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02703207"
    },
    {
      "nct_id": "NCT05237505",
      "title": "The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Chronic Obstructive Pulmonary Disease",
        "Overlap Syndrome"
      ],
      "interventions": [
        {
          "name": "bi-level positive pressure non invasive ventilation",
          "type": "DEVICE"
        },
        {
          "name": "Oxygen gas",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "40 Years to 79 Years"
      },
      "enrollment_count": 240,
      "start_date": "2024-02-13",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05237505"
    },
    {
      "nct_id": "NCT02244957",
      "title": "Right Ventricular Hemodynamics Using Cardiac MRI in Patients COPD and OSA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Chronic Obstructive Pulmonary Disease",
        "Overlap Syndrome"
      ],
      "interventions": [
        {
          "name": "Bi-level positive airway pressure (BPAP)",
          "type": "DEVICE"
        },
        {
          "name": "Nocturnal oxygen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 23,
      "start_date": "2014-09",
      "completion_date": "2020-02",
      "has_results": true,
      "last_update_posted_date": "2020-07-28",
      "last_synced_at": "2026-07-23T03:23:19.888Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02244957"
    }
  ]
}