{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ocular+Hypertension+%28OH%29", "query": { "condition": "Ocular Hypertension (OH)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 11, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ocular+Hypertension+%28OH%29&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-11T09:55:54.800Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01481051", "title": "A Dose Evaluation Study for the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma", "Ocular Hypertension (OH)" ], "interventions": [ { "name": "Latanoprost-PPDS", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 57, "start_date": "2011-11", "completion_date": "2012-09", "has_results": false, "last_update_posted_date": "2013-09-26", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 6, "location_summary": "Artesia, California • Los Angeles, California • San Diego, California + 3 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Roswell", "state": "Georgia" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01481051" }, { "nct_id": "NCT01481077", "title": "A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma", "Ocular Hypertension (OH)" ], "interventions": [ { "name": "Latanoprost-PPDS", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 77, "start_date": "2011-11", "completion_date": "2012-09", "has_results": false, "last_update_posted_date": "2013-09-26", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 11, "location_summary": "Springdale, Arkansas • Denver, Colorado • Danbury, Connecticut + 8 more", "locations": [ { "city": "Springdale", "state": "Arkansas" }, { "city": "Denver", "state": "Colorado" }, { "city": "Danbury", "state": "Connecticut" }, { "city": "Des Peres", "state": "Missouri" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT01481077" }, { "nct_id": "NCT00820300", "title": "A Safety Study of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open Angle Glaucoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Latanoprost-PPDS", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 113, "start_date": "2009-01", "completion_date": "2009-12", "has_results": false, "last_update_posted_date": "2013-09-19", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 1, "location_summary": "Menlo Park, California", "locations": [ { "city": "Menlo Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00820300" }, { "nct_id": "NCT06689696", "title": "24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Glaucoma", "GLAUCOMA 1, OPEN ANGLE, D (Disorder)", "Ocular Hypertension", "Ocular Hypertension (OH)", "Ocular Hypertension Glaucoma", "IOP", "Intraocular Pressure", "Glaucoma Open-Angle", "Glaucoma and Ocular Hypertension", "Glaucoma Patients and Healthy Controls", "Normal Tension Glaucoma (NTG)" ], "interventions": [ { "name": "miLens system", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Smartlens, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "22 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "22 Years to 80 Years" }, "enrollment_count": 86, "start_date": "2025-02-19", "completion_date": "2026-01-06", "has_results": false, "last_update_posted_date": "2026-04-01", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 3, "location_summary": "Fullerton, California • Petaluma, California • Torrance, California", "locations": [ { "city": "Fullerton", "state": "California" }, { "city": "Petaluma", "state": "California" }, { "city": "Torrance", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06689696" }, { "nct_id": "NCT00846989", "title": "Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "RKI983A", "type": "DRUG" }, { "name": "Latanoprost", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 276, "start_date": "2009-01", "completion_date": "2009-04", "has_results": false, "last_update_posted_date": "2020-12-19", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 29, "location_summary": "Artesia, California • Inglewood, California • La Jolla, California + 25 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Inglewood", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Poway", "state": "California" }, { "city": "Stockton", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00846989" }, { "nct_id": "NCT00047593", "title": "Phase 3 Study Comparing IOP Lowering in OAG or OH in Japanese Subjects C-01-98", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Open-Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "IOP Lowering Medications", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": null, "start_date": "2000-01", "completion_date": "2004-07", "has_results": false, "last_update_posted_date": "2008-08-05", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 3, "location_summary": "Los Angeles, California • San Francisco, California • Honolulu, Hawaii", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Honolulu", "state": "Hawaii" } ], "official_url": "https://clinicaltrials.gov/study/NCT00047593" }, { "nct_id": "NCT01037036", "title": "A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Ocular Hypertension", "Open-Angle Glaucoma" ], "interventions": [ { "name": "Latanoprost Punctal Plug Delivery System", "type": "DRUG" }, { "name": "Xalatan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2009-12", "completion_date": "2010-07", "has_results": false, "last_update_posted_date": "2014-01-10", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 1, "location_summary": "Menlo Park, California", "locations": [ { "city": "Menlo Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01037036" }, { "nct_id": "NCT00967811", "title": "A Study of Different Formulations of the L-PPDS in Subjects With OH or OAG", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Formulation E1 of L-PPDS", "type": "DRUG" }, { "name": "Formulation E2 of L-PPDS", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2009-08", "completion_date": "2010-05", "has_results": false, "last_update_posted_date": "2013-09-19", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 1, "location_summary": "Menlo Park, California", "locations": [ { "city": "Menlo Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00967811" }, { "nct_id": "NCT00845299", "title": "Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Latanoprost punctal plug", "type": "DRUG" }, { "name": "artificial tears preserved with Benzalkonium Chloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2009-01", "completion_date": "2009-12", "has_results": false, "last_update_posted_date": "2013-09-19", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 1, "location_summary": "Menlo Park, California", "locations": [ { "city": "Menlo Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00845299" }, { "nct_id": "NCT07400926", "title": "Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Open Angle Glaucoma (OAG)", "Ocular Hypertension (OH)" ], "interventions": [ { "name": "Travoprost", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Glaukos Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2025-12-17", "completion_date": "2026-07", "has_results": false, "last_update_posted_date": "2026-02-27", "last_synced_at": "2026-06-11T09:55:54.800Z", "location_count": 1, "location_summary": "Kenosha, Wisconsin", "locations": [ { "city": "Kenosha", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT07400926" } ] }