{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ocular+Inflammation+and+Pain", "query": { "condition": "Ocular Inflammation and Pain" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 54, "total_pages": 6, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ocular+Inflammation+and+Pain&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-25T02:10:40.856Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02128113", "title": "RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Corneal Endothelial Cell Loss", "Ocular Pain", "Ocular Inflammation", "Cataract Surgery" ], "interventions": [ { "name": "Vehicle Ophthalmic Solution", "type": "DRUG" }, { "name": "Omaveloxolone Ophthalmic Suspension 0.5%", "type": "DRUG" }, { "name": "Omaveloxolone Ophthalmic Suspension 1%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 307, "start_date": "2014-05-31", "completion_date": "2015-04-30", "has_results": true, "last_update_posted_date": "2025-06-03", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 15, "location_summary": "Laguna Hills, California • Lancaster, California • Cape Coral, Florida + 11 more", "locations": [ { "city": "Laguna Hills", "state": "California" }, { "city": "Lancaster", "state": "California" }, { "city": "Cape Coral", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Hoffman Estates", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02128113" }, { "nct_id": "NCT04521140", "title": "Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Corneal Transplant Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Corneal Edema", "Corneal Defect", "Corneal Transplant", "Penetrating KeratoPlasty", "Anterior Chamber Inflammation", "Ocular Pain", "Intraocular Pressure" ], "interventions": [ { "name": "Dextenza 0.4Mg Ophthalmic Insert", "type": "DRUG" }, { "name": "Prednisolone Acetate 1% Oph Susp", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Nicole Fram M.D.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 36, "start_date": "2020-10-16", "completion_date": "2023-01-04", "has_results": false, "last_update_posted_date": "2023-07-24", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04521140" }, { "nct_id": "NCT02163824", "title": "Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Ocular Infections, Irritations and Inflammations" ], "interventions": [ { "name": "KPI-121 0.25%", "type": "DRUG" }, { "name": "KPI-121 1.0%", "type": "DRUG" }, { "name": "Vehicle of KPI-121 0.25%", "type": "DRUG" }, { "name": "Vehicle of KPI-121 1.0%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kala Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 380, "start_date": "2014-05", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2021-01-29", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 23, "location_summary": "Artesia, California • Mission Hills, California • Rancho Cordova, California + 17 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Mission Hills", "state": "California" }, { "city": "Rancho Cordova", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Morrow", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02163824" }, { "nct_id": "NCT02793817", "title": "Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation and Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Post Surgical Ocular Inflammation and Pain" ], "interventions": [ { "name": "KPI-121 1% Ophthalmic Suspension dosed BID", "type": "DRUG" }, { "name": "Vehicle of KPI-121 Ophthalmic Suspension dosed BID", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kala Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 520, "start_date": "2016-06", "completion_date": "2017-03", "has_results": true, "last_update_posted_date": "2020-12-16", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 35, "location_summary": "Chandler, Arizona • Phoenix, Arizona • Artesia, California + 32 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Artesia", "state": "California" }, { "city": "Garden Grove", "state": "California" }, { "city": "Glendale", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02793817" }, { "nct_id": "NCT00853970", "title": "Efficacy Study of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain", "Inflammation" ], "interventions": [ { "name": "Bromfenac Ophthalmic Solution", "type": "DRUG" }, { "name": "Placebo Comparator", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 299, "start_date": "2009-02", "completion_date": "2009-12", "has_results": true, "last_update_posted_date": "2013-01-25", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 1, "location_summary": "Irvine, California", "locations": [ { "city": "Irvine", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00853970" }, { "nct_id": "NCT01298752", "title": "Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation Following Cataract Surgery", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Inflammation", "Pain", "Cataract" ], "interventions": [ { "name": "Mapracorat", "type": "DRUG" }, { "name": "Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 177, "start_date": "2011-02", "completion_date": "2011-11", "has_results": true, "last_update_posted_date": "2020-09-03", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01298752" }, { "nct_id": "NCT02208297", "title": "Loteprednol Etabonate Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Inflammation", "Pain", "Cataract" ], "interventions": [ { "name": "Loteprednol Etabonate Gel (BID)", "type": "DRUG" }, { "name": "Vehicle Gel (BID)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 326, "start_date": "2014-09", "completion_date": "2015-03", "has_results": true, "last_update_posted_date": "2020-09-25", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 1, "location_summary": "Bridgewater, New Jersey", "locations": [ { "city": "Bridgewater", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT02208297" }, { "nct_id": "NCT04739709", "title": "Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Ocular Inflammation and Pain" ], "interventions": [ { "name": "APP13007, 0.05%", "type": "DRUG" }, { "name": "Matching Vehicle Placebo for APP13007, 0.05%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Formosa Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 378, "start_date": "2021-01-11", "completion_date": "2022-03-17", "has_results": true, "last_update_posted_date": "2023-07-20", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 34, "location_summary": "Scottsdale, Arizona • Glendale, California • Hemet, California + 28 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Glendale", "state": "California" }, { "city": "Hemet", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Mission Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04739709" }, { "nct_id": "NCT04781335", "title": "\"A Prospective Study of the Efficacy of Intracameral Dexamethasone (Dexycu™) Compared to Standard of Care Treatment for Post-Cataract Surgical Pain and Anterior Chamber Inflammation\"", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cataract" ], "interventions": [ { "name": "Dexycu", "type": "DRUG" }, { "name": "Standard of Care post operative eye drops (steroid, antibiotic, NSAID)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Eye Institute of West Florida", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "40 Years to 90 Years" }, "enrollment_count": 25, "start_date": "2020-02-20", "completion_date": "2022-12-22", "has_results": false, "last_update_posted_date": "2025-02-25", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 1, "location_summary": "Largo, Florida", "locations": [ { "city": "Largo", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04781335" }, { "nct_id": "NCT04246801", "title": "Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% for the Treatment of Inflammation and Pain Associated With Cataract Surgery (CLOSE-1)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cataract" ], "interventions": [ { "name": "Clobetasol propionate", "type": "DRUG" }, { "name": "Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Salvat", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 250, "start_date": "2020-06-10", "completion_date": "2021-05-19", "has_results": true, "last_update_posted_date": "2022-12-22", "last_synced_at": "2026-09-25T02:10:40.856Z", "location_count": 22, "location_summary": "Chandler, Arizona • Beverly Hills, California • Glendora, California + 19 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Glendora", "state": "California" }, { "city": "Murrieta", "state": "California" }, { "city": "Pasadena", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04246801" } ] }