{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ocular+Surface+Disease&page=2", "query": { "condition": "Ocular Surface Disease", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ocular+Surface+Disease&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-06-10T18:06:37.497Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03945071", "title": "The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dry Eye Syndromes", "Dry Eye", "Ocular Surface Disease" ], "interventions": [ { "name": "Punctal plug", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Oklahoma", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 126, "start_date": "2019-06-01", "completion_date": "2020-10-18", "has_results": false, "last_update_posted_date": "2023-12-07", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 1, "location_summary": "Oklahoma City, Oklahoma", "locations": [ { "city": "Oklahoma City", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT03945071" }, { "nct_id": "NCT04630158", "title": "Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Ocular Pain" ], "interventions": [ { "name": "SAF312 Placebo", "type": "OTHER" }, { "name": "SAF312", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 153, "start_date": "2021-04-21", "completion_date": "2023-06-08", "has_results": true, "last_update_posted_date": "2024-10-09", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 24, "location_summary": "Mission Hills, California • Newport Beach, California • Palo Alto, California + 19 more", "locations": [ { "city": "Mission Hills", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Coral Springs", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04630158" }, { "nct_id": "NCT02042820", "title": "Ocular Surface Immune Response in Dry Eye Disease", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Dry Eye Disease" ], "interventions": [ { "name": "In vivo confocal microscopy (IVCM)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Tufts Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 67, "start_date": "2014-01", "completion_date": "2015-07", "has_results": false, "last_update_posted_date": "2017-10-18", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02042820" }, { "nct_id": "NCT02306668", "title": "Ocular Surface Dry Eye Microbiome", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Dry Eyes" ], "interventions": [], "intervention_types": [], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 80, "start_date": "2014-02", "completion_date": "2016-12", "has_results": false, "last_update_posted_date": "2014-12-03", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT02306668" }, { "nct_id": "NCT00678860", "title": "Validation of Computerized Vision-Targeted Quality-of-Life Questionnaires", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Eye Disease" ], "interventions": [], "intervention_types": [], "sponsor": "National Eye Institute (NEI)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 147, "start_date": "2008-05-09", "completion_date": "2011-10-31", "has_results": false, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00678860" }, { "nct_id": "NCT02322528", "title": "Evaluation of Ocular Surface Inflammatory Mediators Effected by Lotemax", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sjogren's Disease" ], "interventions": [ { "name": "Administration of Lotemax", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "50 Years to 70 Years" }, "enrollment_count": 10, "start_date": "2014-04", "completion_date": "2015-08", "has_results": true, "last_update_posted_date": "2015-10-16", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02322528" }, { "nct_id": "NCT07224529", "title": "Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Meibomian Gland Dysfunction (MGD)" ], "interventions": [ { "name": "Vevye(Cyclosporine 0.1% Ophthalmic Solution)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Alabama at Birmingham", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 48, "start_date": "2026-06-01", "completion_date": "2027-02-01", "has_results": false, "last_update_posted_date": "2026-06-09", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 1, "location_summary": "Birmingham, Alabama", "locations": [ { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT07224529" }, { "nct_id": "NCT04354545", "title": "Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Glaucoma", "Ocular Surface Disease" ], "interventions": [ { "name": "Xiidra (Lifitegrast ophthalmic solution) 5%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 75, "start_date": "2021-04-01", "completion_date": "2026-12-01", "has_results": false, "last_update_posted_date": "2026-03-13", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 1, "location_summary": "Fountain Valley, California", "locations": [ { "city": "Fountain Valley", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04354545" }, { "nct_id": "NCT05758753", "title": "QST for Corneal Nerve Function", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Corneal Disease", "Neuropathy", "Dry Eye Disease", "Neurotrophic Keratitis" ], "interventions": [ { "name": "Quantitative Sensory Test", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Tufts Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 108, "start_date": "2023-05-16", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2026-01-08", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05758753" }, { "nct_id": "NCT07502378", "title": "Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic Keratopathy Patients With Tear Deficiency", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Ocular Surface Disease", "Neurotrophic Keratopathy Stage 1" ], "interventions": [ { "name": "Patients will receive topical Acoltremon 0.003% ophthalmic solution BID in both eyes over an 8 week period.", "type": "DRUG" }, { "name": "Alternative would be patient exiting the trial and starting on tears or other standard of care.", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of South Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2026-03-27", "completion_date": "2027-08-31", "has_results": false, "last_update_posted_date": "2026-03-31", "last_synced_at": "2026-06-10T18:06:37.497Z", "location_count": 1, "location_summary": "Tampa, Florida", "locations": [ { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07502378" } ] }