{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Open+Angle%2C+Low+Risk",
    "query": {
      "condition": "Open Angle, Low Risk"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Open+Angle%2C+Low+Risk&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T23:06:00.821Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07354477",
      "title": "Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Non-proliferative Diabetic Retinopathy (NPDR)",
        "Open-angle Glaucoma (OAG)",
        "Normal Tension Glaucoma (NTG)"
      ],
      "interventions": [
        {
          "name": "QLS-111 Ophthalmic Solution (0.015%)",
          "type": "DRUG"
        },
        {
          "name": "QLS-111 Ophthalmic Solution (0.075%)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Qlaris Bio, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2026-02-20",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07354477"
    },
    {
      "nct_id": "NCT00637130",
      "title": "Safety and Intraocular Pressure (IOP) Lowering Efficacy of Low Dose Travoprost",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Open-angle Glaucoma",
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Travoprost ophthalmic solution, 0.0008%",
          "type": "DRUG"
        },
        {
          "name": "Travoprost ophthalmic solution, 0.001%",
          "type": "DRUG"
        },
        {
          "name": "Travoprost ophthalmic solution, 0.0012%",
          "type": "DRUG"
        },
        {
          "name": "TRAVATAN",
          "type": "DRUG"
        },
        {
          "name": "Vehicle",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 138,
      "start_date": "2007-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2012-12-06",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00637130"
    },
    {
      "nct_id": "NCT03323164",
      "title": "Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Glaucoma; Drugs",
        "Normal Tension Glaucoma",
        "Primary Open-angle Glaucoma"
      ],
      "interventions": [
        {
          "name": "Timolol Maleate",
          "type": "DRUG"
        },
        {
          "name": "Brimonidine Tartrate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wills Eye",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 35,
      "start_date": "2017-07-10",
      "completion_date": "2020-05-30",
      "has_results": true,
      "last_update_posted_date": "2020-12-31",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03323164"
    },
    {
      "nct_id": "NCT01027039",
      "title": "Will Listening to Music Make it Easier to Take a Visual Field Test?",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Wills Eye",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 160,
      "start_date": "2008-06",
      "completion_date": "2009-09",
      "has_results": false,
      "last_update_posted_date": "2016-11-10",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01027039"
    },
    {
      "nct_id": "NCT07300852",
      "title": "DSLT in Normal Tension Glaucoma (NTG) Asian Eyes",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Normal Tension Glaucoma (NTG)",
        "Glaucoma",
        "Open Angle Glaucoma (OAG)",
        "Glaucoma, Open Angle"
      ],
      "interventions": [
        {
          "name": "Direct Selective Laser Trabeculoplasty (DSLT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ngoc Nguyen Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2026-01-01",
      "completion_date": "2028-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 1,
      "location_summary": "San Jose, California",
      "locations": [
        {
          "city": "San Jose",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07300852"
    },
    {
      "nct_id": "NCT00317577",
      "title": "Study of Medical Treatment of Low-Pressure (Normal Tension) Glaucoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Glaucoma, Open Angle"
      ],
      "interventions": [
        {
          "name": "brimonidine, timolol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Chicago Center for Vision Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "1998-12",
      "completion_date": "2004-05",
      "has_results": false,
      "last_update_posted_date": "2006-04-25",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 12,
      "location_summary": "Little Rock, Arkansas • Gainesville, Florida • Palm Beach Gardens, Florida + 7 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Palm Beach Gardens",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00317577"
    },
    {
      "nct_id": "NCT06689696",
      "title": "24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Glaucoma",
        "GLAUCOMA 1, OPEN ANGLE, D (Disorder)",
        "Ocular Hypertension",
        "Ocular Hypertension (OH)",
        "Ocular Hypertension Glaucoma",
        "IOP",
        "Intraocular Pressure",
        "Glaucoma Open-Angle",
        "Glaucoma and Ocular Hypertension",
        "Glaucoma Patients and Healthy Controls",
        "Normal Tension Glaucoma (NTG)"
      ],
      "interventions": [
        {
          "name": "miLens system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Smartlens, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "22 Years to 80 Years"
      },
      "enrollment_count": 86,
      "start_date": "2025-02-19",
      "completion_date": "2026-01-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 3,
      "location_summary": "Fullerton, California • Petaluma, California • Torrance, California",
      "locations": [
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Petaluma",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06689696"
    },
    {
      "nct_id": "NCT02891317",
      "title": "Assessing Ocular Hemodynamic Response to Surgical Intervention in Glaucoma",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Open Angle Glaucoma",
        "Low Tension Glaucoma",
        "Cataract",
        "Ocular Hypertension"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2017-05-08",
      "completion_date": "2017-06-12",
      "has_results": false,
      "last_update_posted_date": "2019-03-05",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02891317"
    },
    {
      "nct_id": "NCT00430287",
      "title": "Does the Optic Disc Grading Done Visually by Your Doctor Agree With Optic Nerve Testing Which is Done by Machines?",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Open Angle Glaucoma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Wills Eye",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "45 Years to 85 Years"
      },
      "enrollment_count": 101,
      "start_date": "2007-03",
      "completion_date": "2008-10",
      "has_results": false,
      "last_update_posted_date": "2016-11-10",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00430287"
    },
    {
      "nct_id": "NCT04433702",
      "title": "Effect of Negative Pressure on Pattern Electroretinography Readings",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glaucoma",
        "Open Angle, Low Risk",
        "Ocular Hypertension",
        "Glaucoma Suspect"
      ],
      "interventions": [
        {
          "name": "Mercury™ Multi-Pressure Dial (MPD) Experimental Goggle",
          "type": "DEVICE"
        },
        {
          "name": "Mercury™ Multi-Pressure Dial (MPD) Placebo Goggle",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vance Thompson Vision",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-10-01",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2024-05-20",
      "last_synced_at": "2026-07-23T23:06:00.821Z",
      "location_count": 1,
      "location_summary": "Sioux Falls, South Dakota",
      "locations": [
        {
          "city": "Sioux Falls",
          "state": "South Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04433702"
    }
  ]
}