{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Open+Fractures&page=2",
    "query": {
      "condition": "Open Fractures",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Open+Fractures&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T01:33:25.103Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04416412",
      "title": "ICG Fluorescence Imaging in Open Fracture Trauma Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Trauma Injury"
      ],
      "interventions": [
        {
          "name": "Immunofluorescence Imaging",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2020-10-01",
      "completion_date": "2026-01-31",
      "has_results": false,
      "last_update_posted_date": "2025-05-01",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 4,
      "location_summary": "Irvine, California • Baltimore, Maryland • Boston, Massachusetts + 1 more",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04416412"
    },
    {
      "nct_id": "NCT03560232",
      "title": "Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Open Fracture",
        "Post-Op Wound Infection"
      ],
      "interventions": [
        {
          "name": "Ceftriaxone",
          "type": "DRUG"
        },
        {
          "name": "Ampicillin/sulbactam",
          "type": "DRUG"
        },
        {
          "name": "Piperacillin/tazobactam",
          "type": "DRUG"
        },
        {
          "name": "Cefazolin + Gentamicin",
          "type": "DRUG"
        },
        {
          "name": "Clindamycin + Gentamicin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mercy Health Ohio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2018-07-09",
      "completion_date": "2020-02-19",
      "has_results": false,
      "last_update_posted_date": "2020-09-11",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 2,
      "location_summary": "Warren, Ohio • Youngstown, Ohio",
      "locations": [
        {
          "city": "Warren",
          "state": "Ohio"
        },
        {
          "city": "Youngstown",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03560232"
    },
    {
      "nct_id": "NCT05980312",
      "title": "Does Early Elbow Motion Improve Patient Outcomes After Surgically Treated Elbow Fractures?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Elbow Fracture",
        "Range of Motion",
        "Immobilization"
      ],
      "interventions": [
        {
          "name": "Splint Immobilization",
          "type": "OTHER"
        },
        {
          "name": "Early Motion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Cooper Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2019-12-27",
      "completion_date": "2023-04-20",
      "has_results": false,
      "last_update_posted_date": "2023-08-07",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 1,
      "location_summary": "Camden, New Jersey",
      "locations": [
        {
          "city": "Camden",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05980312"
    },
    {
      "nct_id": "NCT00689429",
      "title": "Operatively Treated Open Pilon Fractures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Open Pilon Fractures"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2008-05",
      "completion_date": "2010-04-09",
      "has_results": false,
      "last_update_posted_date": "2017-06-20",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00689429"
    },
    {
      "nct_id": "NCT03132246",
      "title": "MICRO Study: Detecting Bacterial Infections Related to Orthopaedic Surgical Implants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Open Reduction and Internal Fixation of Extremity Fractures"
      ],
      "interventions": [
        {
          "name": "Blood draws",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 260,
      "start_date": "2014-04",
      "completion_date": "2018-07-31",
      "has_results": true,
      "last_update_posted_date": "2020-05-15",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03132246"
    },
    {
      "nct_id": "NCT00264511",
      "title": "Hyperbaric Oxygen in Lower Leg Trauma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Tibial Fracture",
        "Soft Tissue Injury"
      ],
      "interventions": [
        {
          "name": "Hyperbaric Oxygen Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Bayside Health",
      "sponsor_class": "OTHER_GOV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2007-02-13",
      "completion_date": "2016-03-23",
      "has_results": false,
      "last_update_posted_date": "2023-09-05",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 1,
      "location_summary": "Concord, California",
      "locations": [
        {
          "city": "Concord",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00264511"
    },
    {
      "nct_id": "NCT06793644",
      "title": "Study of ICG Fluorescence Imaging in Open Fracture and Infection Patients",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fractures, Bone",
        "Trauma Injury"
      ],
      "interventions": [
        {
          "name": "Immunofluorescence Imaging",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2025-06-10",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2026-03-19",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 1,
      "location_summary": "Lebanon, New Hampshire",
      "locations": [
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06793644"
    },
    {
      "nct_id": "NCT00582686",
      "title": "Open Reduction Internal Fixation of Calcaneus Fractures With and Without Bone Graft",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Calcaneus Fractures"
      ],
      "interventions": [
        {
          "name": "ORIF of Calcaneus with bone grafting",
          "type": "PROCEDURE"
        },
        {
          "name": "ORIF of Calcaneus without bone grafting",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2000-05",
      "completion_date": "2008-03",
      "has_results": false,
      "last_update_posted_date": "2013-10-01",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00582686"
    },
    {
      "nct_id": "NCT06055712",
      "title": "Antibiotic Prophylaxis in Pediatric Open Fractures",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Fractures, Open",
        "Infections"
      ],
      "interventions": [
        {
          "name": "Cefazolin",
          "type": "DRUG"
        },
        {
          "name": "Cephalexin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "0 Years to 17 Years"
      },
      "enrollment_count": 800,
      "start_date": "2023-09-11",
      "completion_date": "2034-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06055712"
    },
    {
      "nct_id": "NCT06089525",
      "title": "Treatment of Complex Pilon Fractures",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pilon Fracture"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2023-08-25",
      "completion_date": "2023-12-25",
      "has_results": false,
      "last_update_posted_date": "2023-10-18",
      "last_synced_at": "2026-07-24T01:33:25.103Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06089525"
    }
  ]
}