{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Open+Pilon+Fractures",
    "query": {
      "condition": "Open Pilon Fractures"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T17:25:50.365Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02481869",
      "title": "Platelet Rich Plasma Injection in Pilon Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fracture"
      ],
      "interventions": [
        {
          "name": "Arthrocentesis/PRP",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Arthrocentesis/Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2015-06",
      "completion_date": "2019-11",
      "has_results": true,
      "last_update_posted_date": "2021-02-05",
      "last_synced_at": "2026-06-10T17:25:50.365Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02481869"
    },
    {
      "nct_id": "NCT01789216",
      "title": "Improving Pain Management and Long Term Outcomes Following High Energy Orthopedic Trauma (Pain Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Orthopaedic Fractures"
      ],
      "interventions": [
        {
          "name": "NSAID",
          "type": "DRUG"
        },
        {
          "name": "Gabapentinoids",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Major Extremity Trauma Research Consortium",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 450,
      "start_date": "2013-07",
      "completion_date": "2018-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-02-03",
      "last_synced_at": "2026-06-10T17:25:50.365Z",
      "location_count": 17,
      "location_summary": "Miami, Florida • West Palm Beach, Florida • Indianapolis, Indiana + 13 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01789216"
    },
    {
      "nct_id": "NCT07227493",
      "title": "Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Open Pilon Fractures"
      ],
      "interventions": [
        {
          "name": "Fibergraft Aeridyan Matrix",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2025-10-24",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-12",
      "last_synced_at": "2026-06-10T17:25:50.365Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07227493"
    },
    {
      "nct_id": "NCT00689429",
      "title": "Operatively Treated Open Pilon Fractures",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Open Pilon Fractures"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2008-05",
      "completion_date": "2010-04-09",
      "has_results": false,
      "last_update_posted_date": "2017-06-20",
      "last_synced_at": "2026-06-10T17:25:50.365Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00689429"
    },
    {
      "nct_id": "NCT06089525",
      "title": "Treatment of Complex Pilon Fractures",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pilon Fracture"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2023-08-25",
      "completion_date": "2023-12-25",
      "has_results": false,
      "last_update_posted_date": "2023-10-18",
      "last_synced_at": "2026-06-10T17:25:50.365Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06089525"
    },
    {
      "nct_id": "NCT00582998",
      "title": "Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fracture of Calcaneus, Pilon or Tibial Plateau"
      ],
      "interventions": [
        {
          "name": "Standard Wound Dressing",
          "type": "PROCEDURE"
        },
        {
          "name": "Vacuum Assisted Closure Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 249,
      "start_date": "2001-06",
      "completion_date": "2007-03",
      "has_results": true,
      "last_update_posted_date": "2019-07-25",
      "last_synced_at": "2026-06-10T17:25:50.365Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00582998"
    }
  ]
}