{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Open-angle+Glaucoma+or+Ocular+Hypertension&page=2", "query": { "condition": "Open-angle Glaucoma or Ocular Hypertension", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Open-angle+Glaucoma+or+Ocular+Hypertension&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-06-26T19:26:20.790Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01037036", "title": "A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Ocular Hypertension", "Open-Angle Glaucoma" ], "interventions": [ { "name": "Latanoprost Punctal Plug Delivery System", "type": "DRUG" }, { "name": "Xalatan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2009-12", "completion_date": "2010-07", "has_results": false, "last_update_posted_date": "2014-01-10", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 1, "location_summary": "Menlo Park, California", "locations": [ { "city": "Menlo Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01037036" }, { "nct_id": "NCT01868126", "title": "Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Open-angle Glaucoma or Ocular Hypertension" ], "interventions": [ { "name": "DE-117 ophthalmic solution", "type": "DRUG" }, { "name": "latanoprost ophthalmic solution", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Santen Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 91, "start_date": "2013-05", "completion_date": "2013-09", "has_results": false, "last_update_posted_date": "2018-04-18", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 7, "location_summary": "Newport Beach, California • Morrow, Georgia • Kansas City, Missouri + 4 more", "locations": [ { "city": "Newport Beach", "state": "California" }, { "city": "Morrow", "state": "Georgia" }, { "city": "Kansas City", "state": "Missouri" }, { "city": "Rochester", "state": "New York" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01868126" }, { "nct_id": "NCT01654484", "title": "A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Glaucoma and Ocular Hypertension" ], "interventions": [ { "name": "DE-117", "type": "DRUG" }, { "name": "0.0015% tafluprost", "type": "DRUG" }, { "name": "DE-117 and 0.0015% tafluprost", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Santen Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2012-07", "completion_date": "2012-11", "has_results": false, "last_update_posted_date": "2018-04-18", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 10, "location_summary": "Newport Beach, California • Deerfield Beach, Florida • Largo, Florida + 7 more", "locations": [ { "city": "Newport Beach", "state": "California" }, { "city": "Deerfield Beach", "state": "Florida" }, { "city": "Largo", "state": "Florida" }, { "city": "Morrow", "state": "Georgia" }, { "city": "Roswell", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01654484" }, { "nct_id": "NCT05335122", "title": "A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Open Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "OTX-TIC low dose Travoprost Intracameral Implant", "type": "DRUG" }, { "name": "OTX-TIC high dose Travoprost Intracameral Implant", "type": "DRUG" }, { "name": "Durysta, Bimatoprost Intracameral Implant 10 µg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ocular Therapeutix, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2022-03-16", "completion_date": "2025-01-24", "has_results": false, "last_update_posted_date": "2025-03-21", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 30, "location_summary": "Dothan, Alabama • Huntington Beach, California • Irvine, California + 27 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Irvine", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Pasadena", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05335122" }, { "nct_id": "NCT01528111", "title": "Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Primary Open-angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "LX7101 (0.125%)", "type": "DRUG" }, { "name": "LX7101 (0.25%)", "type": "DRUG" }, { "name": "LX7101 Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Lexicon Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 63, "start_date": "2012-03", "completion_date": "2012-06", "has_results": false, "last_update_posted_date": "2015-09-14", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 5, "location_summary": "Morrow, Georgia • Memphis, Tennessee • Austin, Texas + 2 more", "locations": [ { "city": "Morrow", "state": "Georgia" }, { "city": "Memphis", "state": "Tennessee" }, { "city": "Austin", "state": "Texas" }, { "city": "Houston", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01528111" }, { "nct_id": "NCT00967811", "title": "A Study of Different Formulations of the L-PPDS in Subjects With OH or OAG", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Formulation E1 of L-PPDS", "type": "DRUG" }, { "name": "Formulation E2 of L-PPDS", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mati Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2009-08", "completion_date": "2010-05", "has_results": false, "last_update_posted_date": "2013-09-19", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 1, "location_summary": "Menlo Park, California", "locations": [ { "city": "Menlo Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00967811" }, { "nct_id": "NCT03452033", "title": "H-1337 Ophthalmic Solution Phase 1/2", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Glaucoma, Open-Angle" ], "interventions": [ { "name": "H-1337 Placebo", "type": "DRUG" }, { "name": "H-1337 [1]", "type": "DRUG" }, { "name": "H-1337 [2]", "type": "DRUG" }, { "name": "H-1337 [3]", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Allysta Pharmaceutical", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 87, "start_date": "2018-03-15", "completion_date": "2018-08-15", "has_results": true, "last_update_posted_date": "2022-07-12", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 1, "location_summary": "Goose Creek, South Carolina", "locations": [ { "city": "Goose Creek", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03452033" }, { "nct_id": "NCT06865144", "title": "Effect of Rhopressa on Intraocular Pressure (IOP) in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension Post-SLT", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Primary Open Angle Glaucoma or Ocular Hypertension" ], "interventions": [ { "name": "Netarsudil ophthalmic solution 0.02%", "type": "DRUG" }, { "name": "Artificial tears", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "East Coast Institute for Research", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 70, "start_date": "2025-06-27", "completion_date": "2026-09-01", "has_results": false, "last_update_posted_date": "2026-06-10", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 1, "location_summary": "Jacksonville, Florida", "locations": [ { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06865144" }, { "nct_id": "NCT02207491", "title": "Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Ocular Hypertension", "Open-angle Glaucoma" ], "interventions": [ { "name": "Timolol maleate Ophthalmic Solution 0.5% BID", "type": "DRUG" }, { "name": "AR-13324 Ophthalmic Solution 0.02%", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Aerie Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 411, "start_date": "2014-07", "completion_date": "2015-03", "has_results": true, "last_update_posted_date": "2018-04-13", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 1, "location_summary": "Bedminster, New Jersey", "locations": [ { "city": "Bedminster", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT02207491" }, { "nct_id": "NCT00947661", "title": "Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Open Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "SPARC0912", "type": "DRUG" }, { "name": "Reference0912", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sun Pharma Advanced Research Company Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 578, "start_date": "2010-07", "completion_date": "2012-05", "has_results": true, "last_update_posted_date": "2021-03-09", "last_synced_at": "2026-06-26T19:26:20.790Z", "location_count": 1, "location_summary": "High Point, North Carolina", "locations": [ { "city": "High Point", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00947661" } ] }