{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Opioid+Abuse+%28Disorder%29",
    "query": {
      "condition": "Opioid Abuse (Disorder)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 218,
    "total_pages": 22,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Opioid+Abuse+%28Disorder%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T10:16:39.401Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01884233",
      "title": "Cell Phone Technology Targeting ART Adherence and Drug Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV",
        "Opioid Abuse"
      ],
      "interventions": [
        {
          "name": "Standard Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Text Messaging CBT (TXT-CBT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 62,
      "start_date": "2012-12",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2022-04-29",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01884233"
    },
    {
      "nct_id": "NCT03933865",
      "title": "Acute Pain Management in Patients on Opioid Replacement Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Opioid-use Disorder",
        "Pain, Acute"
      ],
      "interventions": [
        {
          "name": "HYDROmorphone Injectable Solution",
          "type": "DRUG"
        },
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Placebos",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 1,
      "start_date": "2018-10-31",
      "completion_date": "2022-02-24",
      "has_results": false,
      "last_update_posted_date": "2022-10-10",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03933865"
    },
    {
      "nct_id": "NCT03705559",
      "title": "Opioid and Cannabinoid Interactions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Marijuana Usage",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "Vaporized Marijuana",
          "type": "DRUG"
        },
        {
          "name": "Opioid Agonist",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Shanna Babalonis, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 10,
      "start_date": "2019-06-21",
      "completion_date": "2024-02-15",
      "has_results": true,
      "last_update_posted_date": "2025-04-10",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03705559"
    },
    {
      "nct_id": "NCT04758637",
      "title": "AESOPS Trial 2 (AESOPS-2): Availability of Opioid Harm",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Abuse"
      ],
      "interventions": [
        {
          "name": "Overdose Notification",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 61,
      "start_date": "2023-01-23",
      "completion_date": "2024-03-18",
      "has_results": true,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04758637"
    },
    {
      "nct_id": "NCT04827992",
      "title": "Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use",
        "Pain",
        "Marijuana Use"
      ],
      "interventions": [
        {
          "name": "Medical Marijuana",
          "type": "DRUG"
        },
        {
          "name": "Prescription Opioid Taper Support (POTS)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 87,
      "start_date": "2021-08-23",
      "completion_date": "2025-10-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-05",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 3,
      "location_summary": "Portland, Maine • Boston, Massachusetts • Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04827992"
    },
    {
      "nct_id": "NCT03852628",
      "title": "Kappa Opioid Receptor Antagonism for the Tx of AUD and Comorbid PTSD",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post Traumatic Stress Disorder",
        "Alcohol Abuse"
      ],
      "interventions": [
        {
          "name": "2mg Buprenex and 380mg Vivitrol",
          "type": "DRUG"
        },
        {
          "name": "Placebo (SL pill qd, IM injection q4weeks)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pharmacotherapies for Alcohol and Substance Use Disorders Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 69,
      "start_date": "2019-05-20",
      "completion_date": "2023-01-30",
      "has_results": true,
      "last_update_posted_date": "2023-09-14",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 2,
      "location_summary": "Tuscaloosa, Alabama • West Haven, Connecticut",
      "locations": [
        {
          "city": "Tuscaloosa",
          "state": "Alabama"
        },
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03852628"
    },
    {
      "nct_id": "NCT04036968",
      "title": "Enhancing Medication-based Analgesia in Humans- STUDY 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pain",
        "Cannabis",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "Within-subject test of blinded study medications",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 31,
      "start_date": "2020-02-01",
      "completion_date": "2022-11-01",
      "has_results": true,
      "last_update_posted_date": "2023-12-19",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04036968"
    },
    {
      "nct_id": "NCT06271668",
      "title": "Clinical Decision Support to Improve System Naloxone Co-prescribing",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Medication Abuse",
        "Harm Reduction",
        "Opioid Overdose",
        "Opioid Prescribing"
      ],
      "interventions": [
        {
          "name": "Naloxone Co-prescribing Clinical Decision Support (CDS)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "12 Years to 89 Years"
      },
      "enrollment_count": 200000,
      "start_date": "2024-07-01",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06271668"
    },
    {
      "nct_id": "NCT04477304",
      "title": "Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Abuse, Unspecified"
      ],
      "interventions": [
        {
          "name": "Opioid Naive, OR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "At-risk for long-term use, OR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Long-term opioid recipient",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 555,
      "start_date": "2020-12-01",
      "completion_date": "2023-08-06",
      "has_results": true,
      "last_update_posted_date": "2025-08-07",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04477304"
    },
    {
      "nct_id": "NCT02282306",
      "title": "Phone Interview to Prevent Recurring Opioid Overdoses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overdose",
        "Opioid-related Disorders",
        "Drug Addiction",
        "Drug Abuse",
        "Substance Abuse",
        "Opioid Use, Unspecified",
        "Opioid Dependence",
        "Drug Overdose"
      ],
      "interventions": [
        {
          "name": "TTIP-PRO",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2014-09",
      "completion_date": "2015-02",
      "has_results": false,
      "last_update_posted_date": "2015-05-28",
      "last_synced_at": "2026-06-10T10:16:39.401Z",
      "location_count": 2,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02282306"
    }
  ]
}