{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Optic+Nerve+Disease&page=8", "query": { "condition": "Optic Nerve Disease", "page": 8 }, "page_size": 10 }, "pagination": { "page": 8, "page_size": 10, "total_count": 720, "total_pages": 72, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Optic+Nerve+Disease&page=9&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Optic+Nerve+Disease&page=7&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-09T16:57:01.139Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02994719", "title": "Gait Analysis in Neurological Disease", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Parkinson's Disease", "Parkinsonian Disorders", "Atypical Parkinson Disease", "Progressive Supranuclear Palsy", "Multiple System Atrophy", "Corticobasal Degeneration", "Gait, Frontal", "Huntington Disease", "Ataxia, Spinocerebellar" ], "interventions": [ { "name": "Anti-Parkinson medication", "type": "DRUG" }, { "name": "Deep Brain Stimulation", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 120, "start_date": "2016-03-01", "completion_date": "2027-07-07", "has_results": false, "last_update_posted_date": "2026-07-08", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02994719" }, { "nct_id": "NCT00445367", "title": "Biobank For MS And Other Demyelinating Diseases", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Multiple Sclerosis", "Transverse Myelitis", "Neuromyelitis Optica", "Acute Disseminated Encephalomyelitis", "Optic Neuritis" ], "interventions": [], "intervention_types": [], "sponsor": "Accelerated Cure Project for Multiple Sclerosis", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 3226, "start_date": "2006-05", "completion_date": "2036-10", "has_results": false, "last_update_posted_date": "2025-10-02", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 10, "location_summary": "Phoenix, Arizona • Stanford, California • Aurora, Colorado + 7 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Stanford", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00445367" }, { "nct_id": "NCT07623837", "title": "Clinical Validation of AI-Based Quantitative Eye Movement Analysis From Smartphone 9-Gaze Videos (Glandy EOM)", "overall_status": "NOT_YET_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Ocular Motility Disorders", "Strabismus", "Extraocular Muscle Dysfunction", "Thyroid Eye Disease" ], "interventions": [ { "name": "Glandy EOM (AI-based quantitative eye movement analysis software)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "THYROSCOPE INC.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 1000, "start_date": "2026-07-01", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2026-06-03", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 1, "location_summary": "San Jose, California", "locations": [ { "city": "San Jose", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07623837" }, { "nct_id": "NCT03778372", "title": "Methadone for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Emergence Delirium", "Strabismus" ], "interventions": [ { "name": "Methadone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ochsner Health System", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "0 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "0 Years to 18 Years" }, "enrollment_count": 55, "start_date": "2019-01-01", "completion_date": "2020-12-13", "has_results": false, "last_update_posted_date": "2022-07-19", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 1, "location_summary": "Jefferson, Louisiana", "locations": [ { "city": "Jefferson", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03778372" }, { "nct_id": "NCT07217665", "title": "The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen A: AADvac1", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "PSP - Progressive Supranuclear Palsy" ], "interventions": [ { "name": "AADvac1", "type": "BIOLOGICAL" }, { "name": "Matching Placebo", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Adam Boxer", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "41 Years", "maximum_age": "86 Years", "sex": "ALL", "summary": "41 Years to 86 Years" }, "enrollment_count": 146, "start_date": "2026-07-29", "completion_date": "2030-09-28", "has_results": false, "last_update_posted_date": "2026-08-13", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07217665" }, { "nct_id": "NCT00019630", "title": "Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Childhood Soft Tissue Sarcoma", "Childhood Liver Cancer", "Bone Cancer", "Brain Tumor", "Kidney Tumor" ], "interventions": [ { "name": "doxorubicin HCl liposome", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": null, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": null, "start_date": "1999-07", "completion_date": null, "has_results": false, "last_update_posted_date": "2024-03-04", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 2, "location_summary": "Bethesda, Maryland • Philadelphia, Pennsylvania", "locations": [ { "city": "Bethesda", "state": "Maryland" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00019630" }, { "nct_id": "NCT02116959", "title": "Alternating Systemic Chemotherapy and Intra-Arterial Melphalan (IAM) Chemotherapy in Children With Intra-Ocular Retinoblastoma", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Advanced Intra-Ocular Retinoblastoma", "Retinoblastoma" ], "interventions": [ { "name": "Melphalan", "type": "DRUG" }, { "name": "Carboplatin", "type": "DRUG" }, { "name": "Etoposide", "type": "DRUG" }, { "name": "Vincristine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Months", "maximum_age": "18 Years", "sex": "ALL", "summary": "3 Months to 18 Years" }, "enrollment_count": 6, "start_date": "2014-07-23", "completion_date": "2019-05-25", "has_results": false, "last_update_posted_date": "2020-04-16", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02116959" }, { "nct_id": "NCT03713268", "title": "Intraoperative OCT Guidance of Intraocular Surgery II", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Macular Holes", "Epiretinal Membrane", "Diabetic Retinopathy", "Retinal Detachment", "Retinal Disease", "Preretinal Fibrosis", "Cataract", "Ocular Tumor", "Strabismus", "Healthy" ], "interventions": [ { "name": "Microscope integrated optical coherence tomography", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "4 Weeks", "maximum_age": null, "sex": "ALL", "summary": "4 Weeks and older" }, "enrollment_count": 262, "start_date": "2018-09-30", "completion_date": "2027-05-31", "has_results": false, "last_update_posted_date": "2025-10-06", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03713268" }, { "nct_id": "NCT00001549", "title": "Diagnosis and Natural History Study of Patients With Neurological Conditions", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Alzheimer's Disease", "Dementia", "Movement Disorder", "Multiple System Atrophy", "Parkinson's Disease" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 600, "start_date": "1995-10", "completion_date": "2006-01", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001549" }, { "nct_id": "NCT05966467", "title": "Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Neuromyelitis Optica Spectrum Disorder", "NMOSD", "AQP4+ NMOSD" ], "interventions": [], "intervention_types": [], "sponsor": "Alexion Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 122, "start_date": "2024-02-01", "completion_date": "2029-09-27", "has_results": false, "last_update_posted_date": "2026-06-18", "last_synced_at": "2026-10-09T16:57:01.139Z", "location_count": 6, "location_summary": "Washington D.C., District of Columbia • Boston, Massachusetts • Chapel Hill, North Carolina + 3 more", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Chapel Hill", "state": "North Carolina" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Plano", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05966467" } ] }