{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Optic+Neuropathy%2C+Ischemic&page=2",
    "query": {
      "condition": "Optic Neuropathy, Ischemic",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Optic+Neuropathy%2C+Ischemic&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:11:38.224Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00000126",
      "title": "Ischemic Optic Neuropathy Decompression Trial Followup (IONDT Followup)",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ischemic Optic Neuropathy"
      ],
      "interventions": [
        {
          "name": "Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": null,
      "start_date": "1994-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2006-05-26",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 24,
      "location_summary": "Los Angeles, California • San Francisco, California • Gainesville, Florida + 20 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00000126"
    },
    {
      "nct_id": "NCT07290244",
      "title": "Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Open Angle Glaucoma (OAG)",
        "NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)"
      ],
      "interventions": [
        {
          "name": "ER-100 epigenetic therapy",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "Life Biosciences Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 18,
      "start_date": "2026-03-02",
      "completion_date": "2032-03",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 4,
      "location_summary": "Glendale, California • Boston, Massachusetts • New York, New York + 1 more",
      "locations": [
        {
          "city": "Glendale",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07290244"
    },
    {
      "nct_id": "NCT03660618",
      "title": "LSFG-SKIN, Laser Speckle Flowgraphy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Heart Failure",
        "Vascular Ischemia",
        "Burns",
        "Chemotherapy Effect",
        "Radiation Injuries",
        "Uveitis",
        "Scleritis",
        "Multiple Sclerosis",
        "Autonomic Neuropathy",
        "Stroke",
        "Intracranial Hemorrhages",
        "TIA",
        "Migraine",
        "Headache",
        "Pain"
      ],
      "interventions": [
        {
          "name": "laser speckle flowgraphy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Randy Kardon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 1,
      "start_date": "2017-05-23",
      "completion_date": "2019-03-02",
      "has_results": true,
      "last_update_posted_date": "2023-05-10",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03660618"
    },
    {
      "nct_id": "NCT00867815",
      "title": "PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anterior Ischemic Optic Neuropathy"
      ],
      "interventions": [
        {
          "name": "Diagnostic procedures",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "40 Years and older · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2009-07-13",
      "completion_date": "2018-03-28",
      "has_results": true,
      "last_update_posted_date": "2019-01-23",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 11,
      "location_summary": "Vista, California • Atlantis, Florida • Fort Myers, Florida + 7 more",
      "locations": [
        {
          "city": "Vista",
          "state": "California"
        },
        {
          "city": "Atlantis",
          "state": "Florida"
        },
        {
          "city": "Fort Myers",
          "state": "Florida"
        },
        {
          "city": "Fort Myers",
          "state": "Florida"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00867815"
    },
    {
      "nct_id": "NCT02982499",
      "title": "Biomechanics of Optic Neuropathy",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Optic Neuropathy"
      ],
      "interventions": [
        {
          "name": "magnetic resonance image (MRI)",
          "type": "DEVICE"
        },
        {
          "name": "Optical Coherence Tomography (OCT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2016-09",
      "completion_date": "2018-03-26",
      "has_results": false,
      "last_update_posted_date": "2020-10-23",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02982499"
    },
    {
      "nct_id": "NCT03547206",
      "title": "Efficacy & Safety of RPh201 Treatment in Patients With Previous Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nonarteritic Anterior Ischemic Optic Neuropathy"
      ],
      "interventions": [
        {
          "name": "RPh201 Cohort A",
          "type": "DRUG"
        },
        {
          "name": "Placebo Cohort A",
          "type": "OTHER"
        },
        {
          "name": "RPh201 Cohort B",
          "type": "DRUG"
        },
        {
          "name": "Placebo Cohort B",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Regenera Pharma Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 165,
      "start_date": "2018-07-10",
      "completion_date": "2020-09-27",
      "has_results": false,
      "last_update_posted_date": "2020-10-12",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 15,
      "location_summary": "Palo Alto, California • Pasadena, California • Orange, Connecticut + 12 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "Connecticut"
        },
        {
          "city": "Waterbury",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03547206"
    },
    {
      "nct_id": "NCT01411657",
      "title": "NT-501 CNTF Implant for Ischemic Optic Neuropathy: Safety, Neuroprotection and Neuroenhancement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ischemic Optic Neuropathy/Optic Nerve Stroke"
      ],
      "interventions": [
        {
          "name": "NT-501 CNTF Implant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jeffrey L Goldberg",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2011-04",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2016-08-02",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01411657"
    },
    {
      "nct_id": "NCT02795052",
      "title": "Neurologic Stem Cell Treatment Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurologic Disorders",
        "Nervous System Diseases",
        "Neurodegenerative Diseases",
        "Neurological Disorders",
        "Stroke",
        "Traumatic Brain Injury",
        "Cadasil",
        "Chronic Traumatic Encephalopathy",
        "Cerebral Infarction",
        "Cerebral Ischemia",
        "Cerebral Stroke",
        "Cerebral Hemorrhage",
        "Parkinson",
        "Multi-System Degeneration",
        "MSA - Multiple System Atrophy",
        "Progressive Supranuclear Palsy",
        "ALS",
        "Amyotrophic Lateral Sclerosis",
        "Neuropathy",
        "Diabetic Neuropathies",
        "Alzheimer Disease",
        "Dementia",
        "Frontotemporal Dementia",
        "Lewy Body Disease",
        "Cognitive Impairment",
        "Lewy Body Variant of Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Intravenous and Intranasal BMSC",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "MD Stem Cells",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2016-06",
      "completion_date": "2027-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-06",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 2,
      "location_summary": "Westport, Connecticut • Coral Springs, Florida",
      "locations": [
        {
          "city": "Westport",
          "state": "Connecticut"
        },
        {
          "city": "Coral Springs",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02795052"
    },
    {
      "nct_id": "NCT00140491",
      "title": "Vision Restoration Therapy (VRT) to Treat Non-Arteritic Anterior Ischemic Optic Neuropathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-Arteritic Anterior Ischemic Optic Neuropathy"
      ],
      "interventions": [
        {
          "name": "Vision Restoration Therapy (NOVAVISION)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2005-08",
      "completion_date": "2007-04",
      "has_results": false,
      "last_update_posted_date": "2013-10-23",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00140491"
    },
    {
      "nct_id": "NCT02019927",
      "title": "Electric Stimulation of the Eye to Improve Vision After Trauma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)",
        "Trauma",
        "Multiple Sclerosis (MS)"
      ],
      "interventions": [
        {
          "name": "Transcorneal Electrical Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wills Eye",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 97,
      "start_date": "2013-07",
      "completion_date": "2017-09",
      "has_results": true,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-05-22T09:11:38.224Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02019927"
    }
  ]
}