{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Orthodontic+Tooth+Movement",
    "query": {
      "condition": "Orthodontic Tooth Movement"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Orthodontic+Tooth+Movement&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T20:34:34.449Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03299023",
      "title": "The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Orthodontic Tooth Movement",
        "Apnea",
        "Sleep Disordered Breathing"
      ],
      "interventions": [
        {
          "name": "Medibyte Portable Monitor",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Harvard School of Dental Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2017-01-20",
      "completion_date": "2019-06-10",
      "has_results": false,
      "last_update_posted_date": "2018-09-11",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03299023"
    },
    {
      "nct_id": "NCT04226469",
      "title": "Gingival Crevicular Fluid Characterization During Orthodontic Treatment",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy",
        "Maxillary First Premolar Tooth Extraction",
        "Canine Retraction"
      ],
      "interventions": [
        {
          "name": "Tooth movement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "11 Years to 35 Years"
      },
      "enrollment_count": 15,
      "start_date": "2019-01-01",
      "completion_date": "2021-05-05",
      "has_results": true,
      "last_update_posted_date": "2025-05-07",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04226469"
    },
    {
      "nct_id": "NCT02119455",
      "title": "Biomarkers of Orthodontic Tooth Movement With Fixed Appliances and Vibration Appliance Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Movement"
      ],
      "interventions": [
        {
          "name": "Vibration Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "35 Years",
        "sex": "MALE",
        "summary": "15 Years to 35 Years · Male only"
      },
      "enrollment_count": 40,
      "start_date": "2014-04",
      "completion_date": "2018-06",
      "has_results": true,
      "last_update_posted_date": "2019-12-13",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02119455"
    },
    {
      "nct_id": "NCT03421886",
      "title": "Assessment of the Efficacy of the Aerodentis System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthodontic Treatment",
        "Tooth Crowding",
        "Orthodontics"
      ],
      "interventions": [
        {
          "name": "Aerodentis system",
          "type": "DEVICE"
        },
        {
          "name": "Invisalign clear aligner system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "12 Years to 60 Years"
      },
      "enrollment_count": 45,
      "start_date": "2016-07-21",
      "completion_date": "2020-06-30",
      "has_results": true,
      "last_update_posted_date": "2020-11-04",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03421886"
    },
    {
      "nct_id": "NCT05650359",
      "title": "Study of the Use of Orthopulse Photobiomodulation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Orthodontics"
      ],
      "interventions": [
        {
          "name": "OrthoPulse",
          "type": "DEVICE"
        },
        {
          "name": "No intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Biolux Technology GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2022-10-13",
      "completion_date": "2028-05-15",
      "has_results": false,
      "last_update_posted_date": "2024-08-07",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 1,
      "location_summary": "Chandler, Arizona",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05650359"
    },
    {
      "nct_id": "NCT03202355",
      "title": "The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "Fixed Appliance Orthodontic Treatment",
          "type": "DEVICE"
        },
        {
          "name": "OrthoPulse™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biolux Research Holdings, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "11 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2017-04-20",
      "completion_date": "2019-03-11",
      "has_results": false,
      "last_update_posted_date": "2019-04-08",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 3,
      "location_summary": "Chandler, Arizona • Peoria, Arizona • Phoenix, Arizona",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Peoria",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03202355"
    },
    {
      "nct_id": "NCT03398798",
      "title": "Analysis of Orthodontic Tooth Movement Using 3D Imaging",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Crowding",
        "Dental Crowding",
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": ".014\"",
          "type": "DEVICE"
        },
        {
          "name": ".016\"",
          "type": "DEVICE"
        },
        {
          "name": "Twin brackets",
          "type": "DEVICE"
        },
        {
          "name": "Self-ligating brackets",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "10 Years to 45 Years"
      },
      "enrollment_count": 36,
      "start_date": "2018-01-15",
      "completion_date": "2018-11-29",
      "has_results": true,
      "last_update_posted_date": "2020-05-01",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Huntersville, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Huntersville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03398798"
    },
    {
      "nct_id": "NCT02438280",
      "title": "Accelerated Tooth Movement With AcceleDent® and Aligners - a Pilot Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth Movement",
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "AcceleDent, Vibrational Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2015-05",
      "completion_date": "2017-03",
      "has_results": true,
      "last_update_posted_date": "2018-10-30",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02438280"
    },
    {
      "nct_id": "NCT02868554",
      "title": "Accelerated Invisalign Therapy in Conjunction With Acceledent Aura",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "AcceleDent Aura",
          "type": "DEVICE"
        },
        {
          "name": "Accelerated Invisalign therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 34,
      "start_date": "2016-08",
      "completion_date": "2019-04-26",
      "has_results": true,
      "last_update_posted_date": "2020-01-27",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02868554"
    },
    {
      "nct_id": "NCT02954133",
      "title": "The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Malocclusion"
      ],
      "interventions": [
        {
          "name": "Invisalign (7 day)",
          "type": "DEVICE"
        },
        {
          "name": "Invisalign (5 day)",
          "type": "DEVICE"
        },
        {
          "name": "OrthoPulse",
          "type": "DEVICE"
        },
        {
          "name": "Invisalign (3.5 day)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biolux Research Holdings, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 167,
      "start_date": "2016-07",
      "completion_date": "2019-04",
      "has_results": false,
      "last_update_posted_date": "2019-01-15",
      "last_synced_at": "2026-06-10T20:34:34.449Z",
      "location_count": 4,
      "location_summary": "Chandler, Arizona • Maple Grove, Minnesota • Henderson, Nevada + 1 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Maple Grove",
          "state": "Minnesota"
        },
        {
          "city": "Henderson",
          "state": "Nevada"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02954133"
    }
  ]
}