{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Orthognathic+Surgery",
    "query": {
      "condition": "Orthognathic Surgery"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Orthognathic+Surgery&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T01:14:59.396Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06450028",
      "title": "Lidocaine Versus Bupivacaine in Orthognathic Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Numbness",
        "Temperature Sensation",
        "Perception of Touch"
      ],
      "interventions": [
        {
          "name": "10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine",
          "type": "DRUG"
        },
        {
          "name": "6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "15 Years to 35 Years"
      },
      "enrollment_count": 60,
      "start_date": "2024-07-26",
      "completion_date": "2025-11-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-30",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06450028"
    },
    {
      "nct_id": "NCT07245758",
      "title": "Facial iD Customized Mandible Reconstruction Plates",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mandibular Fractures",
        "Mandible Fracture",
        "Mandible; Deformity",
        "MANDIBLE",
        "Orthognathic Surgical Procedures"
      ],
      "interventions": [
        {
          "name": "Mandibular reconstruction",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stryker Craniomaxillofacial",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 50,
      "start_date": "2024-12-01",
      "completion_date": "2026-04-04",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07245758"
    },
    {
      "nct_id": "NCT03844451",
      "title": "Enhanced Recovery With Liposomal Bupivacaine in Orthognathic Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Liposomal Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine and Epinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "15 Years to 25 Years"
      },
      "enrollment_count": 75,
      "start_date": "2019-05-17",
      "completion_date": "2019-11-01",
      "has_results": false,
      "last_update_posted_date": "2019-02-18",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03844451"
    },
    {
      "nct_id": "NCT07245810",
      "title": "Stryker Facial iD Universal Plate Configurator: A Retrospective Post Market Follow Up",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mandibular Fractures",
        "Facial Fracture",
        "Maxilla Fracture",
        "Orthognathic Surgical Procedures"
      ],
      "interventions": [
        {
          "name": "Orthognatic surgery, Reconstructive maxillofacial surgery, Mandible and maxillofacial trauma surgery",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stryker Craniomaxillofacial",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 726,
      "start_date": "2024-11-18",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07245810"
    },
    {
      "nct_id": "NCT00078507",
      "title": "Sensory Re-Training Following Facial Surgery for Correction of Facial Skeletal Disharmony",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Mandibular Advancement"
      ],
      "interventions": [
        {
          "name": "Sensory Re-training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sensory Retraining",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Opening Exercises",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "13 Years to 50 Years"
      },
      "enrollment_count": 186,
      "start_date": "2001-12",
      "completion_date": "2007-03",
      "has_results": false,
      "last_update_posted_date": "2010-02-03",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00078507"
    },
    {
      "nct_id": "NCT06481670",
      "title": "Carbohydrate Fluids and Post Operative Nausea and Vomiting",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nausea, Postoperative",
        "Vomiting, Postoperative"
      ],
      "interventions": [
        {
          "name": "Carbohydrate drink",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2026-06",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-28",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06481670"
    },
    {
      "nct_id": "NCT04117360",
      "title": "Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dentofacial Abnormalities",
        "Dentofacial Deformities",
        "Dentofacial Anomalies, Including Malocclusion",
        "Malocclusion",
        "Malocclusion in Children",
        "Dentofacial Disharmony",
        "Skeletal Malocclusion",
        "Skeletal Malformation",
        "Speech Sound Disorder",
        "Speech Disorders"
      ],
      "interventions": [
        {
          "name": "Orthognathic surgery and Orthodontics",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "15 Years to 40 Years"
      },
      "enrollment_count": 180,
      "start_date": "2019-09-11",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-25",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04117360"
    },
    {
      "nct_id": "NCT04910074",
      "title": "LLLT Effects on Inferior Alveolar Nerve (IAN) Recovery Post-orthognathic Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mandible; Deformity",
        "Surgical Healing",
        "Orthognathic Surgery",
        "Nerve Injury"
      ],
      "interventions": [
        {
          "name": "Low-level laser therapy",
          "type": "DEVICE"
        },
        {
          "name": "Dummy LLLT",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Albert Einstein College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2022-07-01",
      "completion_date": "2024-01-23",
      "has_results": true,
      "last_update_posted_date": "2025-06-24",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04910074"
    },
    {
      "nct_id": "NCT06499181",
      "title": "Multimodal Orthognathic Study Comparing Use of Exparel With Standard of Care.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacain",
          "type": "DRUG"
        },
        {
          "name": "Epinephrin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "United States Naval Medical Center, San Diego",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 86,
      "start_date": "2018-02-28",
      "completion_date": "2020-01-01",
      "has_results": false,
      "last_update_posted_date": "2024-07-19",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06499181"
    },
    {
      "nct_id": "NCT01592708",
      "title": "Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-operative Nausea",
        "Post-operative Vomiting",
        "Nausea Persistent"
      ],
      "interventions": [
        {
          "name": "Antiemetic anesthesia protocol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 233,
      "start_date": "2012-06",
      "completion_date": "2014-04",
      "has_results": true,
      "last_update_posted_date": "2014-08-20",
      "last_synced_at": "2026-06-11T01:14:59.396Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01592708"
    }
  ]
}