{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Osseointegration",
    "query": {
      "condition": "Osseointegration"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 17,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Osseointegration&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T09:41:52.874Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00991393",
      "title": "Sinus Augmentation With Dental Implant",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Maxillary Sinus Bone Loss"
      ],
      "interventions": [
        {
          "name": "INFUSE® Bone Graft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Spinal and Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2009-10",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2012-02-17",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 5,
      "location_summary": "Fullerton, California • Denver, North Carolina • Philadelphia, Pennsylvania + 2 more",
      "locations": [
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00991393"
    },
    {
      "nct_id": "NCT01573026",
      "title": "Five Year Survival Study Evaluating the Genesis Dental Implant System",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Implants"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Keystone Dental, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 120,
      "start_date": "2011-08",
      "completion_date": "2017-07",
      "has_results": false,
      "last_update_posted_date": "2012-04-06",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 8,
      "location_summary": "Newport Beach, California • Woodland Hills, California • Oakbrook Terrace, Illinois + 5 more",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Woodland Hills",
          "state": "California"
        },
        {
          "city": "Oakbrook Terrace",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01573026"
    },
    {
      "nct_id": "NCT06636136",
      "title": "Transtibial Osseointegration",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation; Traumatic, Leg, Lower"
      ],
      "interventions": [
        {
          "name": "OPRA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-05-20",
      "completion_date": "2030-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-30",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06636136"
    },
    {
      "nct_id": "NCT06310239",
      "title": "Microbiome Population Adaptation Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amputation With Osseointegration"
      ],
      "interventions": [
        {
          "name": "Collection of biologic samples and data",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 50,
      "start_date": "2023-12-01",
      "completion_date": "2029-11-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-26",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06310239"
    },
    {
      "nct_id": "NCT05695911",
      "title": "Transfemoral Osseointegrated Prosthesis Limb-Load Symmetry Training",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Transfemoral Amputation",
        "Osseointegration"
      ],
      "interventions": [
        {
          "name": "Limb Load Biofeedback Training Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2023-01-30",
      "completion_date": "2027-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-27",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05695911"
    },
    {
      "nct_id": "NCT05249049",
      "title": "Osseointegrated Transtibial Prosthesis With Neural Interface",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "e-OPRA Implant System for Transtibial Amputees",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 2,
      "start_date": "2021-11-03",
      "completion_date": "2023-04-15",
      "has_results": false,
      "last_update_posted_date": "2022-02-21",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05249049"
    },
    {
      "nct_id": "NCT00991432",
      "title": "Localized Alveolar Ridge Augmentation With Space Maintenance Devices",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alveolar Bone Loss"
      ],
      "interventions": [
        {
          "name": "INFUSE® Bone Graft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Spinal and Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2009-10",
      "completion_date": "2011-03",
      "has_results": false,
      "last_update_posted_date": "2012-02-17",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Greenwood Village, Colorado • Sarasota, Florida + 4 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Greenwood Village",
          "state": "Colorado"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00991432"
    },
    {
      "nct_id": "NCT07645729",
      "title": "Evaluation of a Powered Ankle Prosthesis Capable of Bidirectional Control Via Neural Recording and Cutaneous Stimulation in Free-Space and Walking Tasks",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Powered Prosthesis",
          "type": "DEVICE"
        },
        {
          "name": "Prescribed Prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 10,
      "start_date": "2025-10-21",
      "completion_date": "2031-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-12",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07645729"
    },
    {
      "nct_id": "NCT04827693",
      "title": "The Cortical Shield for Facial Bone Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tooth Loss",
        "Tooth Diseases",
        "Tooth Fracture",
        "Tooth Injuries",
        "Periodontal Bone Loss",
        "Periodontitis",
        "Peri-Implantitis",
        "Tooth Decay"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Verdugo, Fernando, DDS",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2019-01-03",
      "completion_date": "2021-04-05",
      "has_results": false,
      "last_update_posted_date": "2021-04-08",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04827693"
    },
    {
      "nct_id": "NCT06391697",
      "title": "Magnetic Bead Tracking System and eOPRA Implant System With Bionic Prosthesis for Transtibial Amputees",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "eOPRA Implant System for Transtibial Amputees and Magnetic Bead Tracking System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 7,
      "start_date": "2024-05-01",
      "completion_date": "2027-05-02",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-07-22T09:41:52.874Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06391697"
    }
  ]
}