{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Osteochondral+Defect",
    "query": {
      "condition": "Osteochondral Defect"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Osteochondral+Defect&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T12:38:45.151Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06823089",
      "title": "Early Feasibility Study of Cartilage Defect Repair",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Hip",
        "Femoroacetabular Impingement",
        "Osteonecrosis",
        "Legg-Calvé-Perthes Disease",
        "Osteochondral Lesion",
        "Hip Dysplasia"
      ],
      "interventions": [
        {
          "name": "ReNew Hip Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cytex Therapeutics, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "14 Years to 64 Years"
      },
      "enrollment_count": 15,
      "start_date": "2025-11-06",
      "completion_date": "2031-10",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06823089"
    },
    {
      "nct_id": "NCT03262909",
      "title": "Pivotal Study to Evaluate the Safety and Efficacy of GelrinC for Treatment of Cartilage Defects",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Articular Cartilage Defects in the Knee Joint"
      ],
      "interventions": [
        {
          "name": "GelrinC",
          "type": "DEVICE"
        },
        {
          "name": "Microfracture historical control arm",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Regentis Biomaterials",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 181,
      "start_date": "2017-11-14",
      "completion_date": "2024-11",
      "has_results": false,
      "last_update_posted_date": "2022-03-22",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 13,
      "location_summary": "La Mesa, California • Orange, California • Denver, Colorado + 10 more",
      "locations": [
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03262909"
    },
    {
      "nct_id": "NCT03452098",
      "title": "Post-Operative Rehabilitation of Knee Osteochondral Defect: A Case Series",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteochondral Defect",
        "Osteochondritis Dissecans"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "California State University, Northridge",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 5,
      "start_date": "2011-01",
      "completion_date": "2018-11",
      "has_results": false,
      "last_update_posted_date": "2019-02-11",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 1,
      "location_summary": "Northridge, California",
      "locations": [
        {
          "city": "Northridge",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03452098"
    },
    {
      "nct_id": "NCT06915233",
      "title": "A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chondral Defect",
        "Articular Cartilage Defect"
      ],
      "interventions": [
        {
          "name": "autologous cultured chondrocytes on porcine collagen membrane",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Bone Marrow Stimulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Vericel Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "17 Years to 65 Years"
      },
      "enrollment_count": 309,
      "start_date": "2026-05",
      "completion_date": "2030-07",
      "has_results": false,
      "last_update_posted_date": "2026-05-27",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 4,
      "location_summary": "Washington D.C., District of Columbia • Wichita, Kansas • Houston, Texas + 1 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Wichita",
          "state": "Kansas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06915233"
    },
    {
      "nct_id": "NCT03036878",
      "title": "ReNu™ Marrow Stimulation Augmentation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteochondral Defect"
      ],
      "interventions": [
        {
          "name": "ReNu",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NuTech Medical, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 1,
      "start_date": "2017-02-07",
      "completion_date": "2019-12-06",
      "has_results": false,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana • New York, New York",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03036878"
    },
    {
      "nct_id": "NCT02308358",
      "title": "Long Term Outcomes of Osteochondral Allografts for Osteochondral Defects of the Knee",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Outcomes of Allograft"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2014-05",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2023-08-30",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02308358"
    },
    {
      "nct_id": "NCT06311331",
      "title": "Prospective Evaluation of Clinical and Radiographic Outcomes Following Total Talus Replacement (PROCLAIM)",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Avascular Necrosis of the Talus",
        "Talar Osteochondral Defect of Ankle",
        "Talar Dysfunction"
      ],
      "interventions": [
        {
          "name": "Total Talus Replacement (TTR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Restor3D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2024-11-06",
      "completion_date": "2031-11",
      "has_results": false,
      "last_update_posted_date": "2026-01-08",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 1,
      "location_summary": "Charlotte, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06311331"
    },
    {
      "nct_id": "NCT02503228",
      "title": "Clinical Registry Assessment of the Missouri Osteochondral Allograft Preservation System - MOPS",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Symptomatic Osteochondral Defect(s)",
        "Cartilage, Meniscus, Ankle, Knee, Shoulder, Hip"
      ],
      "interventions": [
        {
          "name": "Standard of care osteochondral and or meniscal allograft transplantation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 5000,
      "start_date": "2015-06",
      "completion_date": "2050-12",
      "has_results": false,
      "last_update_posted_date": "2025-07-15",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02503228"
    },
    {
      "nct_id": "NCT03588975",
      "title": "A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chondral Defect",
        "Osteochondritis Dissecans (OCD)",
        "Articular Cartilage Defect",
        "Articular Cartilage Disorder of Knee"
      ],
      "interventions": [
        {
          "name": "MACI",
          "type": "BIOLOGICAL"
        },
        {
          "name": "microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Vericel Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "10 Years to 17 Years"
      },
      "enrollment_count": 45,
      "start_date": "2018-10-24",
      "completion_date": "2030-02",
      "has_results": false,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 12,
      "location_summary": "Palo Alto, California • Sacramento, California • New Orleans, Louisiana + 7 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03588975"
    },
    {
      "nct_id": "NCT01410136",
      "title": "Chondrofix Osteochondral Allograft Prospective Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Articular Cartilage Disorder",
        "Degeneration; Articular Cartilage",
        "Chronic Cartilage Injury",
        "Acute Cartilage Injury",
        "Defect of Articular Cartilage"
      ],
      "interventions": [
        {
          "name": "Chondrofix Osteochondral Allograft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Zimmer Orthobiologics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 29,
      "start_date": "2011-04",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2014-08-11",
      "last_synced_at": "2026-07-22T12:38:45.151Z",
      "location_count": 5,
      "location_summary": "Cos Cob, Connecticut • New Haven, Connecticut • Greenwood, Indiana + 2 more",
      "locations": [
        {
          "city": "Cos Cob",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Greenwood",
          "state": "Indiana"
        },
        {
          "city": "Chestnut Hill",
          "state": "Massachusetts"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01410136"
    }
  ]
}