{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Otitis+Media+With+Effusion&page=2",
    "query": {
      "condition": "Otitis Media With Effusion",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Otitis+Media+With+Effusion&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T05:25:41.230Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00016497",
      "title": "Adenoidectomy for Otitis Media in 2-3 Year Old Children",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Otitis Media With Effusion"
      ],
      "interventions": [
        {
          "name": "bilateral myringotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "bilateral myringotomy and tubes",
          "type": "PROCEDURE"
        },
        {
          "name": "adenoidectomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Institute on Deafness and Other Communication Disorders (NIDCD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Months",
        "maximum_age": "47 Months",
        "sex": "ALL",
        "summary": "24 Months to 47 Months"
      },
      "enrollment_count": null,
      "start_date": "1997-02",
      "completion_date": "2007-01",
      "has_results": false,
      "last_update_posted_date": "2006-04-24",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00016497"
    },
    {
      "nct_id": "NCT00736112",
      "title": "Food Allergy - Tubes - Adenoids (FATA) Trial",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Otitis Media With Effusion",
        "Food Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Food Allergy Testing",
          "type": "OTHER"
        },
        {
          "name": "Adenoidectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "BMT",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "4 Years",
        "sex": "ALL",
        "summary": "Up to 4 Years"
      },
      "enrollment_count": 0,
      "start_date": "2008-10",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2016-09-30",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00736112"
    },
    {
      "nct_id": "NCT01949155",
      "title": "OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Otitis Media With Effusion"
      ],
      "interventions": [
        {
          "name": "OTO-201",
          "type": "DRUG"
        },
        {
          "name": "Sham",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Otonomy, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Months to 17 Years"
      },
      "enrollment_count": 266,
      "start_date": "2013-11",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2016-11-11",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01949155"
    },
    {
      "nct_id": "NCT00365092",
      "title": "Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Otitis Media",
        "Middle Ear Effusion"
      ],
      "interventions": [
        {
          "name": "Insertion of tympanostomy tubes",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "61 Days",
        "sex": "ALL",
        "summary": "0 Years to 61 Days"
      },
      "enrollment_count": 400,
      "start_date": "2002-04",
      "completion_date": "2005-03",
      "has_results": false,
      "last_update_posted_date": "2006-08-17",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00365092"
    },
    {
      "nct_id": "NCT03655665",
      "title": "Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Otitis Media"
      ],
      "interventions": [
        {
          "name": "Ofloxacin otic solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "6 Months to 10 Years"
      },
      "enrollment_count": 125,
      "start_date": "2019-05-16",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2024-07-09",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 1,
      "location_summary": "Waltham, Massachusetts",
      "locations": [
        {
          "city": "Waltham",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03655665"
    },
    {
      "nct_id": "NCT06191562",
      "title": "Posterior vs. Anterior Tympanostomy Tube Placement",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Otitis Media in Children",
        "Chronic Otitis Media With Effusion",
        "Recurrent Acute Otitis Media"
      ],
      "interventions": [
        {
          "name": "Tympanostomy tube",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "David Chi, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "6 Months to 14 Years"
      },
      "enrollment_count": 386,
      "start_date": "2024-02-29",
      "completion_date": "2028-02",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania • Sewickley, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Sewickley",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06191562"
    },
    {
      "nct_id": "NCT05915078",
      "title": "Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Otitis Media With Effusion",
        "Acute Otitis Media",
        "Otitis Media"
      ],
      "interventions": [
        {
          "name": "Iontophoresis and tube placement",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Months to 17 Years"
      },
      "enrollment_count": 200,
      "start_date": "2023-06-15",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-07-23",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 6,
      "location_summary": "Louisville, Kentucky • Cherry Hill, New Jersey • New Brunswick, New Jersey + 3 more",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Cherry Hill",
          "state": "New Jersey"
        },
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Ogden",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05915078"
    },
    {
      "nct_id": "NCT00939796",
      "title": "Clinical Study of the Tympanostomy Tube Delivery System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Otitis Media With Effusion"
      ],
      "interventions": [
        {
          "name": "Acclarent Tympanostomy Tube Delivery System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Integra LifeSciences Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 16,
      "start_date": "2009-03",
      "completion_date": "2009-07",
      "has_results": true,
      "last_update_posted_date": "2024-08-06",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 2,
      "location_summary": "Biloxi, Mississippi • San Antonio, Texas",
      "locations": [
        {
          "city": "Biloxi",
          "state": "Mississippi"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00939796"
    },
    {
      "nct_id": "NCT01251432",
      "title": "Risk Factors and Potential Causes of Eustachian Tube Dysfunction in Adults",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Eustachian Tube Dysfunction",
        "Chronic Otitis Media"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2010-06",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2016-11-04",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01251432"
    },
    {
      "nct_id": "NCT00279916",
      "title": "Short Term Relief of Eustachian Tube Dysfunction and Serous Otitis Media Using Intranasal Steroid Sprays",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Otitis Media, Serous",
        "Negative Middle Ear Pressure",
        "Rhinitis",
        "Otitis Media With Effusion",
        "Otitis Media, Secretory"
      ],
      "interventions": [
        {
          "name": "Triamcinolone acetonide nasal spray",
          "type": "DRUG"
        },
        {
          "name": "Placebo nasal spray",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "6 Years to 100 Years"
      },
      "enrollment_count": 91,
      "start_date": "2005-09-01",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-06-10T05:25:41.230Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00279916"
    }
  ]
}