{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ototoxicity",
    "query": {
      "condition": "Ototoxicity"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 25,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ototoxicity&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-21T22:22:31.390Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00458887",
      "title": "Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ototoxicity",
        "Unspecified Childhood Solid Tumor, Protocol Specific"
      ],
      "interventions": [
        {
          "name": "management of therapy complications",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Children's Oncology Group",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Year to 18 Years"
      },
      "enrollment_count": 301,
      "start_date": "2007-05",
      "completion_date": "2017-02-28",
      "has_results": false,
      "last_update_posted_date": "2017-03-13",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 73,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 65 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Madera",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00458887"
    },
    {
      "nct_id": "NCT06500975",
      "title": "Long Term Outcomes After Vestibular Implantation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bilateral Vestibular Hypofunction",
        "Bilateral Vestibular Deficiency",
        "Bilateral Vestibulopathy",
        "Gentamicin Ototoxicity",
        "Aminoglycoside Toxicity",
        "Vestibular Diseases",
        "Sensation Disorders",
        "Labyrinth Diseases",
        "Other Disorders of Vestibular Function"
      ],
      "interventions": [
        {
          "name": "Labyrinth Devices MVI™ Multichannel Vestibular Implant System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "22 Years to 90 Years"
      },
      "enrollment_count": 32,
      "start_date": "2024-12-01",
      "completion_date": "2029-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06500975"
    },
    {
      "nct_id": "NCT02890030",
      "title": "The Platinum Study Comparison Group",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Testicular Neoplasms"
      ],
      "interventions": [
        {
          "name": "Questionnaire",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Lawrence Einhorn",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "18 Years to 55 Years · Male only"
      },
      "enrollment_count": 102,
      "start_date": "2015-05",
      "completion_date": "2017-06-14",
      "has_results": false,
      "last_update_posted_date": "2020-04-08",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02890030"
    },
    {
      "nct_id": "NCT02819856",
      "title": "SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ototoxicity"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "SPI-1005 Ebselen 200mg Capsule x1",
          "type": "DRUG"
        },
        {
          "name": "SPI-1005 Ebselen 200mg Capsule x2",
          "type": "DRUG"
        },
        {
          "name": "SPI-1005 Ebselen 200mg Capsule x3",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sound Pharmaceuticals, Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2017-07-21",
      "completion_date": "2023-04-07",
      "has_results": false,
      "last_update_posted_date": "2024-08-02",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02819856"
    },
    {
      "nct_id": "NCT05676944",
      "title": "Vestibular Implantation in Older Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Other Disorders of Vestibular Function, Bilateral",
        "Bilateral Vestibular Deficiency (BVD)",
        "Gentamicin Ototoxicity",
        "Labyrinth Diseases",
        "Vestibular Diseases",
        "Sensation Disorders",
        "Bilateral Vestibular Hypofunction",
        "Bilateral Vestibulopathy",
        "Presbyvestibulopathy",
        "Aminoglycoside Ototoxicity"
      ],
      "interventions": [
        {
          "name": "Labyrinth Devices MVI™ Multichannel Vestibular Implant System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "65 Years to 90 Years"
      },
      "enrollment_count": 15,
      "start_date": "2023-04-11",
      "completion_date": "2028-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-12",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05676944"
    },
    {
      "nct_id": "NCT01263262",
      "title": "A Comparison of Infection Rates Between Two Surgical Sites",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Corneal Toxicity",
        "Ototoxicity",
        "Surgical Site Infection"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2011-01",
      "completion_date": "2013-08",
      "has_results": false,
      "last_update_posted_date": "2013-10-24",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01263262"
    },
    {
      "nct_id": "NCT05674786",
      "title": "Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Other Disorders of Vestibular Function, Bilateral",
        "Bilateral Vestibular Deficiency (BVD)",
        "Gentamicin Ototoxicity",
        "Labyrinth Diseases",
        "Vestibular Diseases",
        "Sensation Disorders",
        "Bilateral Vestibular Hypofunction",
        "Bilateral Vestibulopathy",
        "Aminoglycoside Ototoxicity"
      ],
      "interventions": [
        {
          "name": "Labyrinth Devices MVI™ Multichannel Vestibular Implant System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "22 Years to 90 Years"
      },
      "enrollment_count": 8,
      "start_date": "2023-02-28",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-12",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05674786"
    },
    {
      "nct_id": "NCT02099786",
      "title": "Randomized Trial Comparison of Ototoxicity Monitoring Programs",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cisplatin Ototoxicity",
        "Hearing Loss"
      ],
      "interventions": [
        {
          "name": "COMP-VA",
          "type": "OTHER"
        },
        {
          "name": "Standard of care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 47,
      "start_date": "2015-04-01",
      "completion_date": "2018-05-05",
      "has_results": true,
      "last_update_posted_date": "2019-10-09",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02099786"
    },
    {
      "nct_id": "NCT00584155",
      "title": "Protection From Cisplatin Ototoxicity by Lactated Ringers",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hearing Loss"
      ],
      "interventions": [
        {
          "name": "Normal Saline and 0.3% ofloxacin",
          "type": "DRUG"
        },
        {
          "name": "Lactated Ringer's with 0.03% Ofloxacin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2006-07",
      "completion_date": "2010-06",
      "has_results": false,
      "last_update_posted_date": "2015-05-27",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00584155"
    },
    {
      "nct_id": "NCT05756660",
      "title": "Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Ototoxicity, Drug-Induced"
      ],
      "interventions": [
        {
          "name": "Sodium Thiosulfate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "1 Month to 39 Years"
      },
      "enrollment_count": 33,
      "start_date": "2023-03-01",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-05-21T22:22:31.390Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05756660"
    }
  ]
}