{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ovarian+Function+Insufficiency",
    "query": {
      "condition": "Ovarian Function Insufficiency"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Ovarian+Function+Insufficiency&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T14:14:26.267Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04948658",
      "title": "Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Turner Syndrome",
        "Post-menarcheal Adolescents",
        "Ovarian Disfunction",
        "Galactosemia",
        "Variations in Sex Characteristics",
        "Differences in Sex Development"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "2 Years to 35 Years"
      },
      "enrollment_count": 200,
      "start_date": "2021-09-13",
      "completion_date": "2030-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04948658"
    },
    {
      "nct_id": "NCT00001275",
      "title": "Ovarian Follicle Function in Patients With Primary Ovarian Failure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amenorrhea",
        "Hypoaldosteronism",
        "Hypogonadism",
        "Infertility",
        "Premature Ovarian Failure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "42 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 42 Years · Female only"
      },
      "enrollment_count": 1134,
      "start_date": "1991-05-12",
      "completion_date": "2017-02-08",
      "has_results": false,
      "last_update_posted_date": "2017-10-06",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001275"
    },
    {
      "nct_id": "NCT06866119",
      "title": "Effects of Estrogen on Heart Health in Women With Primary Ovarian Insufficiency",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Ovarian Insufficiency",
        "Premature Menopause",
        "Metabolic Complications",
        "Endothelial Function (FMD)",
        "Estrogen Replacement Therapy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 40 Years · Female only"
      },
      "enrollment_count": 45,
      "start_date": "2026-03-01",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06866119"
    },
    {
      "nct_id": "NCT03187353",
      "title": "IMProving Executive Function Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cognitive Impairment",
        "RRSO"
      ],
      "interventions": [
        {
          "name": "Lisdexamfetamine",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral capsule",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "58 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 58 Years · Female only"
      },
      "enrollment_count": 69,
      "start_date": "2017-09-22",
      "completion_date": "2022-04-30",
      "has_results": true,
      "last_update_posted_date": "2023-11-18",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03187353"
    },
    {
      "nct_id": "NCT00429403",
      "title": "Goserelin Acetate Study for Ovarian Function in Patients With Primary Breast Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Goserelin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "46 Years",
        "sex": "FEMALE",
        "summary": "15 Years to 46 Years · Female only"
      },
      "enrollment_count": 1,
      "start_date": "2006-08",
      "completion_date": "2010-07",
      "has_results": true,
      "last_update_posted_date": "2016-05-09",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00429403"
    },
    {
      "nct_id": "NCT06583395",
      "title": "Quest to Analyze One Thousand Humans Meditating",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amyotrophic Lateral Sclerosis (ALS)",
        "Angina, Stable",
        "Anxiety",
        "Asthma",
        "Atrial Fibrillation",
        "Cancer Brain",
        "Cancer, Breast",
        "Cancer Colon",
        "Cancer, Lung",
        "Cancer, Ovarian",
        "Cancer Prostate",
        "Cancer Skin",
        "Throat Cancer",
        "Lymphoma",
        "Cancer, Thyroid",
        "Cancer, Other",
        "Cerebral Palsy",
        "Chronic Fatigue Syndrome",
        "Cluster Headache",
        "Chronic Obstructive Pulmonary Disease (COPD)",
        "Chronic Kidney Diseases",
        "Crohn Disease",
        "Deafness",
        "Depression",
        "Diabetes",
        "Eczema",
        "Epilepsy",
        "Fibroids",
        "Fibromyalgia",
        "Heart Failure",
        "Hypertension",
        "Hyperthyroidism",
        "Hypothyroidism",
        "Irritable Bowel Syndrome (IBS)",
        "Infertility",
        "Lyme Disease",
        "Macular Degeneration",
        "Migraine",
        "Multiple Allergies",
        "Multiple Sclerosis",
        "Osteoarthritis",
        "Osteoporosis",
        "Ovarian Cysts",
        "Parkinson Disease",
        "Phantom Limb Pain",
        "Psoriasis",
        "Post Traumatic Stress Disorder (PTSD)",
        "Rheumatoid Arthritis",
        "Sjogrens Disease",
        "Spinal Cord Injury",
        "Spinal Stenosis",
        "Stroke",
        "Tension Headache",
        "Tinnitus",
        "Ulcerative Colitis"
      ],
      "interventions": [
        {
          "name": "Advanced multi-component meditation practice",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Tobias Moeller-Bertram",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 3000,
      "start_date": "2021-12-05",
      "completion_date": "2025-03-25",
      "has_results": false,
      "last_update_posted_date": "2024-11-01",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Palm Desert, California",
      "locations": [
        {
          "city": "Palm Desert",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06583395"
    },
    {
      "nct_id": "NCT00429494",
      "title": "GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Amenorrhea",
        "Premature Ovarian Failure",
        "Ovarian Function Insufficiency"
      ],
      "interventions": [
        {
          "name": "Leuprolide Acetate",
          "type": "DRUG"
        },
        {
          "name": "Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hematopoietic Stem Cell Transplantation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "Up to 40 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2002-11",
      "completion_date": "2011-06",
      "has_results": true,
      "last_update_posted_date": "2013-07-09",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00429494"
    },
    {
      "nct_id": "NCT03692572",
      "title": "Influence of Early Menopause on Sympathetic Activation and Cardiovascular Function in Older Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Early Menopause",
        "Menopause"
      ],
      "interventions": [
        {
          "name": "Nitrate supplementation",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "60 Years to 70 Years · Female only"
      },
      "enrollment_count": 22,
      "start_date": "2018-08-01",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-06-12",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03692572"
    },
    {
      "nct_id": "NCT00507780",
      "title": "Effect of Cetrorelex Acetate on Ovarian Function in Women Undergoing Chemotherapy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Ovarian Function",
        "Preservation of Ovarian Function"
      ],
      "interventions": [
        {
          "name": "GnRH antagonist",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "21 Years",
        "sex": "FEMALE",
        "summary": "10 Years to 21 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2007-07-18",
      "completion_date": "2010-07-22",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00507780"
    },
    {
      "nct_id": "NCT00370019",
      "title": "Effects of an Estrogen Replacement Therapy Skin Patch on Ovulation in Women With Premature Ovarian Failure",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Premature Ovarian Failure"
      ],
      "interventions": [
        {
          "name": "Estradiol/Medroxyprogesterone acetate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2006-08-25",
      "completion_date": "2011-12-12",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-07-22T14:14:26.267Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00370019"
    }
  ]
}