{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Overdose%2C+Drug",
    "query": {
      "condition": "Overdose, Drug"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 162,
    "total_pages": 17,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Overdose%2C+Drug&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-27T00:18:57.839Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05877118",
      "title": "Improving Availability of Intranasal Naloxone",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Overdose"
      ],
      "interventions": [
        {
          "name": "Enhanced Overdose Education (EOE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Hartford Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 84,
      "start_date": "2024-03-01",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-06-07",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 2,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05877118"
    },
    {
      "nct_id": "NCT02770339",
      "title": "Pharmacogenomic Profiling of Pediatric Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mental Disorders",
        "Metabolism Medication Toxicity",
        "Pediatric Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Years to 18 Years"
      },
      "enrollment_count": 100,
      "start_date": "2016-06",
      "completion_date": "2017-11-30",
      "has_results": false,
      "last_update_posted_date": "2018-02-20",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02770339"
    },
    {
      "nct_id": "NCT05506267",
      "title": "Development of a Tracheal Sound Sensor",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Insufficiency",
        "Opioid Overdose",
        "Hypoventilation"
      ],
      "interventions": [
        {
          "name": "Trachea Sound Sensor (TSS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 20,
      "start_date": "2020-06-01",
      "completion_date": "2022-04-30",
      "has_results": false,
      "last_update_posted_date": "2022-08-18",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05506267"
    },
    {
      "nct_id": "NCT04811014",
      "title": "Young Houston Emergency Opioid Engagement System",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Opioid-use Disorder",
        "Opioid Dependence",
        "Opioid Overdose",
        "Opioid Use",
        "Substance Use Disorders"
      ],
      "interventions": [
        {
          "name": "Buprenorphine, Naloxone Drug Combination",
          "type": "DRUG"
        },
        {
          "name": "Individual Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Peer Recovery Support Services",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Support Group",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Referral to Medication Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Assertive Outreach",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 250,
      "start_date": "2021-04-19",
      "completion_date": "2030-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04811014"
    },
    {
      "nct_id": "NCT04634279",
      "title": "Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid-use Disorder",
        "Addiction",
        "Depression",
        "Post Traumatic Stress Disorder",
        "Suicidal Ideation"
      ],
      "interventions": [
        {
          "name": "Collaborative care Plus",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "RAND",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2022-08-31",
      "completion_date": "2024-06-12",
      "has_results": false,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 12,
      "location_summary": "Los Angeles, California • Santa Monica, California • Albuquerque, New Mexico + 3 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        },
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04634279"
    },
    {
      "nct_id": "NCT03489161",
      "title": "Feasibility of the Utilization of Buprenorphine in the Emergency Room to Treat Clinical Opioid Withdrawal",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Drug Overdose",
        "Opioid Withdrawal",
        "Opioid-use Disorder"
      ],
      "interventions": [
        {
          "name": "Buprenorphine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 3,
      "start_date": "2018-08-01",
      "completion_date": "2018-08-28",
      "has_results": false,
      "last_update_posted_date": "2018-12-13",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03489161"
    },
    {
      "nct_id": "NCT07219082",
      "title": "Behavioral Safety and Fentanyl Education: BSAFE",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Drug Overdose",
        "Drug Overdose Accidental"
      ],
      "interventions": [
        {
          "name": "BSAFE Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "San Francisco Department of Public Health",
      "sponsor_class": "OTHER_GOV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2026-06-15",
      "completion_date": "2030-01-15",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07219082"
    },
    {
      "nct_id": "NCT06768814",
      "title": "Overdose Recovery and Care Access (ORCA) Qualitative Stakeholder Interviews and County-level Data",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use Disorder",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "Sub-acute stabilization",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40000,
      "start_date": "2024-12-15",
      "completion_date": "2029-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06768814"
    },
    {
      "nct_id": "NCT03241771",
      "title": "Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Abuse",
        "Overdose",
        "Risk Behavior"
      ],
      "interventions": [
        {
          "name": "Naloxone Navigator 1.0",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 325,
      "start_date": "2017-08-14",
      "completion_date": "2022-08-31",
      "has_results": false,
      "last_update_posted_date": "2023-08-24",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03241771"
    },
    {
      "nct_id": "NCT06238128",
      "title": "Opioid Rapid Response System: Naloxone Training in Communities",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Overdose"
      ],
      "interventions": [
        {
          "name": "Opioid Rapid Resonse System (ORRS) training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Non-active opioid overdose response training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 773,
      "start_date": "2024-05-24",
      "completion_date": "2025-12-29",
      "has_results": false,
      "last_update_posted_date": "2026-01-23",
      "last_synced_at": "2026-06-27T00:18:57.839Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06238128"
    }
  ]
}