{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=PROM+%28Pregnancy%29",
    "query": {
      "condition": "PROM (Pregnancy)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 46,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=PROM+%28Pregnancy%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:45:05.483Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07119398",
      "title": "Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preterm PROM (Pregnancy)"
      ],
      "interventions": [
        {
          "name": "Oxytocin plus Foley Catheter",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Oxytocin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DRUG"
      ],
      "sponsor": "Eastern Virginia Medical School",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 80,
      "start_date": "2025-07-14",
      "completion_date": "2026-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-13",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07119398"
    },
    {
      "nct_id": "NCT01973036",
      "title": "FOLCROM Trial: Foley Catheter in Rupture of Membranes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Rupture of Membranes"
      ],
      "interventions": [
        {
          "name": "Foley Catheter",
          "type": "DEVICE"
        },
        {
          "name": "Oxytocin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Geisinger Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 201,
      "start_date": "2014-03",
      "completion_date": "2016-08",
      "has_results": true,
      "last_update_posted_date": "2018-09-24",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 5,
      "location_summary": "Phoenix, Arizona • Newark, Delaware • Allentown, Pennsylvania + 2 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Allentown",
          "state": "Pennsylvania"
        },
        {
          "city": "Danville",
          "state": "Pennsylvania"
        },
        {
          "city": "Wilkes-Barre",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01973036"
    },
    {
      "nct_id": "NCT04451109",
      "title": "Dilapan-S®: A Multicenter US E-registry",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post Term Pregnancy",
        "Premature Rupture of Membrane",
        "Fetal Growth Retardation",
        "Oligohydramnios",
        "Gestational Diabetes",
        "High Blood Pressure in Pregnancy"
      ],
      "interventions": [
        {
          "name": "Dilapan-S",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medicem Technology s.r.o.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 1200,
      "start_date": "2020-12-01",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-11-22",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04451109"
    },
    {
      "nct_id": "NCT00294242",
      "title": "Safety Study of Membrane Sweeping in Pregnancy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy",
        "Prelabor Rupture of Membranes"
      ],
      "interventions": [
        {
          "name": "Membrane Sweep",
          "type": "PROCEDURE"
        },
        {
          "name": "No Membrane Sweep",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Tripler Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 300,
      "start_date": "2006-02",
      "completion_date": "2007-05",
      "has_results": false,
      "last_update_posted_date": "2025-02-11",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 1,
      "location_summary": "Tripler AMC, Hawaii",
      "locations": [
        {
          "city": "Tripler AMC",
          "state": "Hawaii"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00294242"
    },
    {
      "nct_id": "NCT00724594",
      "title": "Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chorioamnionitis",
        "Brain Injury"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine",
          "type": "DRUG"
        },
        {
          "name": "Control",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2008-08",
      "completion_date": "2014-08",
      "has_results": true,
      "last_update_posted_date": "2021-04-12",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00724594"
    },
    {
      "nct_id": "NCT02997345",
      "title": "PPROM Registry (Preterm Premature Rupture of Membranes)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fetal Membranes, Premature Rupture",
        "Preterm Premature Rupture of the Membranes",
        "Oligohydramnios",
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "There is no intervention associated with this study.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "American Alliance for pProm Support",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "14 Years to 55 Years · Female only"
      },
      "enrollment_count": 3000,
      "start_date": "2013-07",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02997345"
    },
    {
      "nct_id": "NCT05603624",
      "title": "Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chorioamnionitis",
        "Intrauterine Infection",
        "Postpartum Endometritis",
        "Puerperal Infection"
      ],
      "interventions": [
        {
          "name": "Cervical examination to assess labor",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Eastern Virginia Medical School",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 163,
      "start_date": "2021-09-02",
      "completion_date": "2022-09-01",
      "has_results": false,
      "last_update_posted_date": "2023-08-25",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05603624"
    },
    {
      "nct_id": "NCT00342277",
      "title": "Microarray Expression Profiling to Identify Stereotypic mRNA Profiles in Human Parturition",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preterm Birth",
        "Premature Rupture of Membranes"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 6838,
      "start_date": "1999-12-21",
      "completion_date": "2016-05-05",
      "has_results": false,
      "last_update_posted_date": "2023-02-24",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00342277"
    },
    {
      "nct_id": "NCT04318470",
      "title": "Identification of Microbial DNA in Maternal Plasma After PPROM",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preterm Rupture of Membranes"
      ],
      "interventions": [
        {
          "name": "mNGS",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 70,
      "start_date": "2020-02-12",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-04-07",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04318470"
    },
    {
      "nct_id": "NCT04478942",
      "title": "PROMMO Trial: Oral Misoprostol vs IV Oxytocin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Premature Rupture of Membrane",
        "Induction of Labor Affected Fetus / Newborn"
      ],
      "interventions": [
        {
          "name": "Misoprostol Oral Product",
          "type": "DRUG"
        },
        {
          "name": "Intravenous Oxytocin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 138,
      "start_date": "2020-10-26",
      "completion_date": "2025-01-14",
      "has_results": false,
      "last_update_posted_date": "2025-08-28",
      "last_synced_at": "2026-05-22T09:45:05.483Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04478942"
    }
  ]
}