{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pacemaker+Malfunction",
    "query": {
      "condition": "Pacemaker Malfunction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 28,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pacemaker+Malfunction&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T06:17:33.075Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00589303",
      "title": "AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "FDA approved rate and rhythm control drugs",
          "type": "DRUG"
        },
        {
          "name": "AV Node ablation and device implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2007-12",
      "completion_date": "2011-07",
      "has_results": true,
      "last_update_posted_date": "2013-04-04",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 5,
      "location_summary": "Scottsdale, Arizona • Evansville, Indiana • Rochester, Minnesota + 2 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Evansville",
          "state": "Indiana"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00589303"
    },
    {
      "nct_id": "NCT00370526",
      "title": "HEAL-HF: A Cardiac Resynchronization Therapy (CRT) Outcomes Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure, Congestive"
      ],
      "interventions": [
        {
          "name": "Acute hemodynamic assessment using PV Loops (CD Leycom, The Netherlands) during LV lead placement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Stereotaxis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2007-02",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2008-01-11",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 3,
      "location_summary": "Gainesville, Georgia • Charleston, South Carolina • Richmond, Virginia",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Georgia"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00370526"
    },
    {
      "nct_id": "NCT05704426",
      "title": "Arrythmia Burden in Cardiac Contractility Modulation (CCM)",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrial Fibrillation",
        "Arrythmia"
      ],
      "interventions": [
        {
          "name": "Impulse Dynamics Optimizer Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Hackensack Meridian Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2023-05-01",
      "completion_date": "2023-07-18",
      "has_results": true,
      "last_update_posted_date": "2024-08-19",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 1,
      "location_summary": "Hackensack, New Jersey",
      "locations": [
        {
          "city": "Hackensack",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05704426"
    },
    {
      "nct_id": "NCT02111980",
      "title": "RF Surgical Sponge-Detecting System on the Function of Pacemakers and Implantable Cardioverter Defibrillators",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiomyopathy",
        "Cardiac Arrhythmia",
        "Heart Failure",
        "Chronic Thromboembolic Pulmonary Hypertension"
      ],
      "interventions": [
        {
          "name": "RF Assure Scanning",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2014-03",
      "completion_date": "2015-05",
      "has_results": true,
      "last_update_posted_date": "2019-12-24",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02111980"
    },
    {
      "nct_id": "NCT00708058",
      "title": "Use of Defibrillator Information in the Emergency Department",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congestive Heart Failure",
        "Medical Device"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2007-08",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2012-03-20",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00708058"
    },
    {
      "nct_id": "NCT02421549",
      "title": "Remote Interrogation in Rural Emergency Departments",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Disease",
        "Cardiovascular Disease",
        "Heart Failure",
        "Arrhythmias, Cardiac"
      ],
      "interventions": [
        {
          "name": "Unpaired remote monitoring transmitter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2014-12",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2019-02-04",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02421549"
    },
    {
      "nct_id": "NCT02191696",
      "title": "Observational Study of ICD and Pacemaker Sensing in the Presence of IMED-4 Operation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "IMED-4 recording",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Intersection Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2014-06",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2015-01-30",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 2,
      "location_summary": "Encinitas, California • Palm Springs, California",
      "locations": [
        {
          "city": "Encinitas",
          "state": "California"
        },
        {
          "city": "Palm Springs",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02191696"
    },
    {
      "nct_id": "NCT04159454",
      "title": "PITA-HF: Feasibility, Safety, and Tolerability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure",
        "Dilated Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "PITA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2020-11-20",
      "completion_date": "2023-02-01",
      "has_results": false,
      "last_update_posted_date": "2023-02-14",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04159454"
    },
    {
      "nct_id": "NCT00253357",
      "title": "PROSPECT: Predictors of Response to Cardiac Re-Synchronization Therapy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure",
        "Congestive Heart Failure",
        "Cardiomyopathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Medtronic Cardiac Rhythm and Heart Failure",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 450,
      "start_date": "2004-03",
      "completion_date": "2006-06",
      "has_results": false,
      "last_update_posted_date": "2007-12-21",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 16,
      "location_summary": "Several Locations, California • Gainsville, Florida • Atlanta, Georgia + 13 more",
      "locations": [
        {
          "city": "Several Locations",
          "state": "California"
        },
        {
          "city": "Gainsville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Columbus",
          "state": "Illinois"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00253357"
    },
    {
      "nct_id": "NCT02145351",
      "title": "Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure With a Preserved Ejection Fraction",
        "Heart Failure, Diastolic",
        "Chronotropic Incompetence"
      ],
      "interventions": [
        {
          "name": "Rate adaptive atrial pacing using a dual-chamber pacemaker",
          "type": "DEVICE"
        },
        {
          "name": "Pacemaker system will be implanted but set to Pacing Off.",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2014-04-07",
      "completion_date": "2022-05-09",
      "has_results": true,
      "last_update_posted_date": "2023-04-05",
      "last_synced_at": "2026-09-04T06:17:33.075Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02145351"
    }
  ]
}