{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pain+Dysfunction",
    "query": {
      "condition": "Pain Dysfunction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 194,
    "total_pages": 20,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pain+Dysfunction&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T08:27:22.015Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01264965",
      "title": "Non-cancer Pain and Cognitive Impairment: A Disabling Relationship",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Arthritis",
        "Pain",
        "Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "long acting oxycodone",
          "type": "DRUG"
        },
        {
          "name": "extra strength acetaminophen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2011-01",
      "completion_date": "2014-02",
      "has_results": true,
      "last_update_posted_date": "2020-12-11",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01264965"
    },
    {
      "nct_id": "NCT01053507",
      "title": "Treximet for Prevention of Post Traumatic Headache Associated With Cognitive Dysfunction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Post-Traumatic Headache"
      ],
      "interventions": [
        {
          "name": "sumatriptan/naproxen sodium",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cady, Roger, M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 23,
      "start_date": "2010-05",
      "completion_date": "2012-11",
      "has_results": true,
      "last_update_posted_date": "2020-07-29",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 3,
      "location_summary": "Springfield, Missouri • Nashville, Tennessee • Temple, Texas",
      "locations": [
        {
          "city": "Springfield",
          "state": "Missouri"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Temple",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01053507"
    },
    {
      "nct_id": "NCT06729151",
      "title": "Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bladder Pain Syndrome",
        "Female Sexual Dysfunction"
      ],
      "interventions": [
        {
          "name": "Onabotulinum toxin A",
          "type": "DRUG"
        },
        {
          "name": "Conservative management (dietary and behavioral)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 99 Years · Female only"
      },
      "enrollment_count": 159,
      "start_date": "2024-11-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-12-11",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06729151"
    },
    {
      "nct_id": "NCT02197429",
      "title": "Acupuncture for the Treatment of Vulvodynia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vulvodynia",
        "Vulvar Vestibulitis",
        "Pain",
        "Dyspareunia",
        "Female Sexual Dysfunction Due to Physical Condition"
      ],
      "interventions": [
        {
          "name": "Acupuncture",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Schlaeger, Judith M., CNM, LAc, PhD",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 36,
      "start_date": "2012-02",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2014-07-22",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 1,
      "location_summary": "Glenview, Illinois",
      "locations": [
        {
          "city": "Glenview",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02197429"
    },
    {
      "nct_id": "NCT06218407",
      "title": "Development and Evaluation of Computerized Chemosensory Based Orbitofrontal Networks Training for Treatment of Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Pain",
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) short burst paradigm",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) long burst paradigm",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Computerized Chemosensory-Based Orbitofrontal Cortex Training plus beta caryophyllene (CBOT-Plus)",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT)",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Evon Medics LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 86,
      "start_date": "2023-04-27",
      "completion_date": "2023-09-15",
      "has_results": false,
      "last_update_posted_date": "2024-01-23",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06218407"
    },
    {
      "nct_id": "NCT01142349",
      "title": "Cognitive Behavioral Therapy for Arthritis Pain and Insomnia in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Dysfunction",
        "Sleep Disturbance",
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Lifestyles A",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lifestyles B",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lifestyles C",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 367,
      "start_date": "2009-01",
      "completion_date": "2013-08",
      "has_results": false,
      "last_update_posted_date": "2013-12-19",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 2,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01142349"
    },
    {
      "nct_id": "NCT02449902",
      "title": "TXV13-01 Estradiol Vaginal Softgel Capsules in Treating Postmenopausal Women With Symptoms of Vulvar and Vaginal Atrophy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Menopause",
        "Vulvovaginal Atrophy",
        "Painful Intercourse",
        "Dyspareunia"
      ],
      "interventions": [
        {
          "name": "Estradiol",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "TherapeuticsMD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 75 Years · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2013-07",
      "completion_date": "2013-09",
      "has_results": true,
      "last_update_posted_date": "2015-12-14",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 1,
      "location_summary": "DeLand, Florida",
      "locations": [
        {
          "city": "DeLand",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02449902"
    },
    {
      "nct_id": "NCT04060875",
      "title": "Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Pain",
        "Low Back Pain",
        "Fibromyalgia",
        "Upper Extremity Dysfunction",
        "Complex Regional Pain Syndromes",
        "Phantom Limb Pain",
        "Rheumatoid Arthritis",
        "Carpal Tunnel Syndrome",
        "Repetitive Strain Injury"
      ],
      "interventions": [
        {
          "name": "Karuna Labs Virtual Reality Software",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Karuna Labs Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2017-09-21",
      "completion_date": "2021-06-01",
      "has_results": false,
      "last_update_posted_date": "2021-06-11",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04060875"
    },
    {
      "nct_id": "NCT02295644",
      "title": "Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia: Randomized Single Blinded Investigational Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Temporomandibular Joint Dysfunction Syndrome"
      ],
      "interventions": [
        {
          "name": "Ultrasound Sonicator 740",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 28,
      "start_date": "2014-11",
      "completion_date": "2015-10",
      "has_results": true,
      "last_update_posted_date": "2018-06-07",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02295644"
    },
    {
      "nct_id": "NCT05129332",
      "title": "Vaginal Dilator Therapy Among Women With Gynecologic and Breast Cancers Experiencing Dyspareunia",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dyspareunia"
      ],
      "interventions": [
        {
          "name": "Vaginal Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "Vaginal Dilator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2022-08-03",
      "completion_date": "2024-02-07",
      "has_results": false,
      "last_update_posted_date": "2024-04-04",
      "last_synced_at": "2026-07-24T08:27:22.015Z",
      "location_count": 2,
      "location_summary": "New York, New York • Providence, Rhode Island",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05129332"
    }
  ]
}