{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pain+and+Anxiety",
    "query": {
      "condition": "Pain and Anxiety"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 341,
    "total_pages": 35,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pain+and+Anxiety&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T02:18:03.286Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03238976",
      "title": "Nature Sounds as a Pain and Anxiety Reducing Strategy in Patients Undergoing Breast Core Biopsy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Nature sounds",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 200,
      "start_date": "2017-09-11",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-04",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03238976"
    },
    {
      "nct_id": "NCT01411943",
      "title": "Epigenetics and Psychoneurologic Symptoms in Women With Breast Cancer",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "81 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 81 Years · Female only"
      },
      "enrollment_count": 75,
      "start_date": "2011-01",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2015-12-08",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 2,
      "location_summary": "Newport News, Virginia • Richmond, Virginia",
      "locations": [
        {
          "city": "Newport News",
          "state": "Virginia"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01411943"
    },
    {
      "nct_id": "NCT00785135",
      "title": "Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Binocular Dysfunction",
        "Vertical Heterophoria",
        "Vision, Binocular",
        "Vision Disparity"
      ],
      "interventions": [
        {
          "name": "Lenses containing prismatic correction",
          "type": "DEVICE"
        },
        {
          "name": "Lenses not containing prismatic correction",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vision Specialists of Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2008-11",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2020-10-12",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 1,
      "location_summary": "Birmingham, Michigan",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00785135"
    },
    {
      "nct_id": "NCT07122843",
      "title": "VR AI Meditation for Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain and Anxiety"
      ],
      "interventions": [
        {
          "name": "VR Guided Meditation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Christopher Almario",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2025-11-06",
      "completion_date": "2027-01-20",
      "has_results": false,
      "last_update_posted_date": "2025-11-26",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07122843"
    },
    {
      "nct_id": "NCT04942561",
      "title": "VR to Reduce Pain/Anxiety During IV Starts",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Radiology"
      ],
      "interventions": [
        {
          "name": "Samsung Gear VR",
          "type": "DEVICE"
        },
        {
          "name": "Merge VR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "10 Years to 21 Years"
      },
      "enrollment_count": 107,
      "start_date": "2017-04-12",
      "completion_date": "2019-07-24",
      "has_results": false,
      "last_update_posted_date": "2021-07-01",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04942561"
    },
    {
      "nct_id": "NCT05708586",
      "title": "Virtual Reality Decreases Child Anxiety and Pain as Well as Caregiver Anxiety and Pain Perception During Orthopaedic Clinic Office Procedures",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Virtual Reality (VR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "4 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2021-12-08",
      "completion_date": "2023-01-25",
      "has_results": true,
      "last_update_posted_date": "2024-03-27",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05708586"
    },
    {
      "nct_id": "NCT05830201",
      "title": "The Presence of a Therapy Dog Reduces Pain and Anxiety During Pediatric Elbow Pin Removal",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Elbow Injury"
      ],
      "interventions": [
        {
          "name": "No Dog Present",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Dog is Present",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "3 Years to 10 Years"
      },
      "enrollment_count": 52,
      "start_date": "2024-10-01",
      "completion_date": "2026-01-06",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05830201"
    },
    {
      "nct_id": "NCT07317271",
      "title": "VR-PMR for Post-Burn Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burn",
        "Chronic Pain Following Thermal Burn Injury",
        "Non-Pharmacological Interventions",
        "Virtual Reality",
        "Sleep Disturbance",
        "Anxiety",
        "Depressive Symptoms",
        "Fatigue Symptom",
        "Pruritus",
        "Burn Injury",
        "Progressive Muscle Relaxation"
      ],
      "interventions": [
        {
          "name": "Virtual Reality-Enhanced Progressive Muscle Relaxation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Progressive Muscle Relaxation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2026-02-27",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07317271"
    },
    {
      "nct_id": "NCT06644573",
      "title": "Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Insomnia",
        "Sleep Deprivation",
        "REM Behavior Disorder",
        "REM Sleep Behavior Disorder",
        "REM Sleep Measurement",
        "Insomnia",
        "Insomnia Related to Specified Disorder",
        "Insomnia Due to Other Mental Disorder",
        "Insomnia Comorbid to Psychiatric Disorder",
        "Insomnia Due to Anxiety and Fear",
        "Insomnia Related to Another Mental Condition",
        "Insomnia Disorders",
        "Idiopathic Hypersomnia",
        "Sleep Disorders, Circadian Rhythm",
        "Post Trauma Nightmares",
        "PTSD - Post Traumatic Stress Disorder",
        "Sleep Quality",
        "Anesthesia",
        "Anxiety",
        "Depression",
        "Mental Health",
        "Alzheimer Disease or Associated Disorder",
        "Parkinsons",
        "Circadian Rhythm",
        "Circadian Dysregulation",
        "PTSD",
        "Post-Traumatic",
        "Post-Traumatic Stress Disorder Complex",
        "Military Combat Stress Reaction",
        "Sleep",
        "Military Activity",
        "Veterans",
        "Shift Work Sleep Disorder",
        "Menopause Related Conditions",
        "Pain",
        "Cancer Pain",
        "Athletes"
      ],
      "interventions": [
        {
          "name": "PROSOMNIA Sleep Therapy™ (PSTx)",
          "type": "PROCEDURE"
        },
        {
          "name": "Anesthesia-Induced Sleep Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Diprivan (propofol), Astra-Zeneca",
          "type": "DRUG"
        },
        {
          "name": "Continuous EEG Monitoring",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Nyree Penn",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-11-01",
      "completion_date": "2026-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-28",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 1,
      "location_summary": "Aventura, Florida",
      "locations": [
        {
          "city": "Aventura",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06644573"
    },
    {
      "nct_id": "NCT01902966",
      "title": "Feasibility - Beta Adrenergic Blockade (BB) in Cervical Cancer (CX)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervical Cancer"
      ],
      "interventions": [
        {
          "name": "Propranolol",
          "type": "DRUG"
        },
        {
          "name": "Diary",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Relaxation Audio Recording",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Questionnaires",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2013-09-11",
      "completion_date": "2020-08-14",
      "has_results": true,
      "last_update_posted_date": "2021-10-12",
      "last_synced_at": "2026-06-11T02:18:03.286Z",
      "location_count": 2,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01902966"
    }
  ]
}