{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pain+and+Anxiety&page=5",
    "query": {
      "condition": "Pain and Anxiety",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 356,
    "total_pages": 36,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pain+and+Anxiety&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pain+and+Anxiety&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-10T11:54:22.173Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01198197",
      "title": "PET Brain and Whole Body Distribution Studies for Nociceptin/Orphanin FQ Peptide (NOP) Receptor Using [11C]NOP-1A",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pain",
        "Anxiety",
        "Depression"
      ],
      "interventions": [
        {
          "name": "NOP-1A",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 41,
      "start_date": "2010-09-03",
      "completion_date": "2014-02-28",
      "has_results": false,
      "last_update_posted_date": "2019-12-17",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01198197"
    },
    {
      "nct_id": "NCT06723158",
      "title": "Oral Surgery Virtual Reality Glasses Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Procedural Anxiety",
        "Procedural Pain"
      ],
      "interventions": [
        {
          "name": "Virtual reality (VR) glasses with relaxation module",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "16 Years to 65 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-11-18",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-27",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06723158"
    },
    {
      "nct_id": "NCT05267704",
      "title": "Evaluating the Feasibility of VR for Pediatric Renal Biopsies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain, Procedural",
        "Procedural Anxiety",
        "Sedation Complication"
      ],
      "interventions": [
        {
          "name": "Oculus Go Virtual Reality Headset",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "5 Years to 17 Years"
      },
      "enrollment_count": 32,
      "start_date": "2022-10-11",
      "completion_date": "2024-09-10",
      "has_results": true,
      "last_update_posted_date": "2026-03-12",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05267704"
    },
    {
      "nct_id": "NCT06835504",
      "title": "Morphine or Ketamine for Analgesia",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Abdominal Pain",
        "Isolated Extremity Fracture",
        "Pain",
        "Pediatrics"
      ],
      "interventions": [
        {
          "name": "Ketamine hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Morphine sulphate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 1010,
      "start_date": "2026-09-01",
      "completion_date": "2030-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Sacramento, California • Wilmington, Delaware + 5 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06835504"
    },
    {
      "nct_id": "NCT02953691",
      "title": "Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anxiety",
        "Pain",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Galacto-Oligosaccharide",
          "type": "DRUG"
        },
        {
          "name": "Maltodextrin (Placebo)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jeff Taekman, M.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2017-06-09",
      "completion_date": "2018-01-01",
      "has_results": false,
      "last_update_posted_date": "2018-01-31",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02953691"
    },
    {
      "nct_id": "NCT02660385",
      "title": "Insomnia Self-Management in Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Failure",
        "Heart Failure",
        "Congestive Heart Failure",
        "Heart Failure, Congestive",
        "Sleep Initiation and Maintenance Disorders",
        "Chronic Insomnia",
        "Disorders of Initiating and Maintaining Sleep",
        "Fatigue",
        "Pain",
        "Depressive Symptoms",
        "Sleep Disorders",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-Management Education for Heart Failure",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 195,
      "start_date": "2016-03-07",
      "completion_date": "2021-11-30",
      "has_results": true,
      "last_update_posted_date": "2023-02-09",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02660385"
    },
    {
      "nct_id": "NCT06186960",
      "title": "Tandem VR: Synchronized Nature-Based Experiences in Virtual Reality for Hospice Patients and Their Caregivers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hospice",
        "End of Life",
        "Palliative Care",
        "Pain",
        "Anxiety",
        "Fear of Death"
      ],
      "interventions": [
        {
          "name": "Tandem Virtual Reality",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Prisma Health-Upstate",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2024-03-01",
      "completion_date": "2025-04-30",
      "has_results": true,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 1,
      "location_summary": "Seneca, South Carolina",
      "locations": [
        {
          "city": "Seneca",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06186960"
    },
    {
      "nct_id": "NCT04687085",
      "title": "Mindful Meditation for Epidural Catheter Placement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Pain"
      ],
      "interventions": [
        {
          "name": "10 minute mindful meditation recording",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2020-12-21",
      "completion_date": "2021-11-30",
      "has_results": false,
      "last_update_posted_date": "2022-03-04",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04687085"
    },
    {
      "nct_id": "NCT02697435",
      "title": "Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain",
        "Hip Ostearthritis",
        "Myofascial Pain Syndrome",
        "Fibromyalgia",
        "Depression",
        "Maladaptive Coping",
        "Lumbar Spinal Stenosis",
        "Insomnia",
        "Sacroiliac Joint Pain",
        "Lateral Hip and Thigh Pain",
        "Anxiety",
        "Dementia",
        "Recent Leg Length Discrepancy"
      ],
      "interventions": [
        {
          "name": "Patient-Centered Care",
          "type": "OTHER"
        },
        {
          "name": "Imaging-Directed Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "60 Years to 89 Years"
      },
      "enrollment_count": 55,
      "start_date": "2016-04-01",
      "completion_date": "2018-08-31",
      "has_results": true,
      "last_update_posted_date": "2019-08-19",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania • Richmond, Virginia",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02697435"
    },
    {
      "nct_id": "NCT07221786",
      "title": "Preoperative Opioid Tapering Before Spine Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Consumption, Postoperative",
        "Pain After Surgery",
        "Opioid Dependency"
      ],
      "interventions": [
        {
          "name": "Opioid tapering with CBT and education",
          "type": "OTHER"
        },
        {
          "name": "Opioid tapering with education alone",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2025-12-01",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-24",
      "last_synced_at": "2026-10-10T11:54:22.173Z",
      "location_count": 1,
      "location_summary": "Philadephia, Pennsylvania",
      "locations": [
        {
          "city": "Philadephia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07221786"
    }
  ]
}