{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Paranasal+Sinus+Diseases&page=16", "query": { "condition": "Paranasal Sinus Diseases", "page": 16 }, "page_size": 10 }, "pagination": { "page": 16, "page_size": 10, "total_count": 474, "total_pages": 48, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Paranasal+Sinus+Diseases&page=17&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Paranasal+Sinus+Diseases&page=15&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-15T02:58:09.896Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03867461", "title": "The Effects of MAP and EtCO2 on Venous Sinus Pressures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Idiopathic Intracranial Hypertension" ], "interventions": [ { "name": "Venous Sinus Stenting", "type": "PROCEDURE" }, { "name": "Adjustment to end-tidal carbon dioxide concentrations ( 38-40 mmHg range)", "type": "OTHER" }, { "name": "Adjustment to Mean Arterial Pressure (100-110 mmHg range)", "type": "OTHER" }, { "name": "Adjustment to Mean Arterial Pressure (60-80 mmHg range)", "type": "OTHER" }, { "name": "Adjustment to end-tidal carbon dioxide concentrations (24-26 mmHg range)", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 8, "start_date": "2019-06-20", "completion_date": "2019-09-25", "has_results": false, "last_update_posted_date": "2020-05-12", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03867461" }, { "nct_id": "NCT01156142", "title": "Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Head and Neck Cancer", "Mucositis", "Oral Complications of Radiation Therapy", "Pain" ], "interventions": [ { "name": "doxepin hydrochloride", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 155, "start_date": "2010-12", "completion_date": "2015-03-02", "has_results": true, "last_update_posted_date": "2017-08-09", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 120, "location_summary": "Scottsdale, Arizona • Hartford, Connecticut • Jacksonville, Florida + 77 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Augusta", "state": "Georgia" }, { "city": "Boise", "state": "Idaho" } ], "official_url": "https://clinicaltrials.gov/study/NCT01156142" }, { "nct_id": "NCT00552773", "title": "Pilot Study to Determine Efficacy of Cyclamen Europaeum Extract Nasal Spray in Patients With Acute Sinusitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "ACUTE SINUSITIS" ], "interventions": [ { "name": "Cyclamen Europaeum", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Dey", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 48, "start_date": "2007-11", "completion_date": "2009-12", "has_results": false, "last_update_posted_date": "2013-06-04", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 25, "location_summary": "Birmingham, Alabama • Oxford, Alabama • Jonesboro, Arkansas + 19 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Oxford", "state": "Alabama" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "Gainsville", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00552773" }, { "nct_id": "NCT00262470", "title": "Treatment of Orthostatic Intolerance", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Tachycardia", "Chronic Orthostatic Intolerance" ], "interventions": [ { "name": "Acetazolamide", "type": "DRUG" }, { "name": "Atomoxetine", "type": "DRUG" }, { "name": "NO Drug", "type": "OTHER" }, { "name": "Clonidine", "type": "DRUG" }, { "name": "Entacapone", "type": "DRUG" }, { "name": "Entacapone & Propranolol", "type": "DRUG" }, { "name": "Atomoxetine & Propranolol", "type": "DRUG" }, { "name": "Indomethacin", "type": "DRUG" }, { "name": "Mecamylamine", "type": "DRUG" }, { "name": "Isosorbide Dinitrate", "type": "DRUG" }, { "name": "Melatonin", "type": "DIETARY_SUPPLEMENT" }, { "name": "Midodrine", "type": "DRUG" }, { "name": "Modafinil", "type": "DRUG" }, { "name": "Octreotide", "type": "DRUG" }, { "name": "Placebo", "type": "RADIATION" }, { "name": "Propranolol", "type": "DRUG" }, { "name": "Modafinil & Propranolol", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "IV Saline", "type": "PROCEDURE" }, { "name": "Drinking Water", "type": "OTHER" }, { "name": "Breathing Device", "type": "DEVICE" }, { "name": "memantine", "type": "DRUG" }, { "name": "Abdominal binder", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "OTHER", "DIETARY_SUPPLEMENT", "RADIATION", "PROCEDURE", "DEVICE" ], "sponsor": "Satish R. Raj", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 150, "start_date": "1997-04", "completion_date": "2029-12", "has_results": false, "last_update_posted_date": "2025-10-08", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00262470" }, { "nct_id": "NCT00245440", "title": "Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Maxillary Sinusitis" ], "interventions": [ { "name": "Azithromycin", "type": "DRUG" }, { "name": "Telithromycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "CPL Associates", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 192, "start_date": "2005-12", "completion_date": "2006-07", "has_results": false, "last_update_posted_date": "2007-10-31", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 1, "location_summary": "Taylors, South Carolina", "locations": [ { "city": "Taylors", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00245440" }, { "nct_id": "NCT01391910", "title": "Response Shift in Sinus Surgery Outcomes", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Chronic Rhinosinusitis" ], "interventions": [], "intervention_types": [], "sponsor": "Greg Davis", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 32, "start_date": "2011-06", "completion_date": "2013-06", "has_results": false, "last_update_posted_date": "2013-12-12", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01391910" }, { "nct_id": "NCT01121445", "title": "The Impact of Daily Sinus Irrigation on Nasal Symptoms in Continuous Positive Airway Pressure (CPAP) Users - A Pilot Study", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Obstructive Sleep Apnea" ], "interventions": [ { "name": "NeilMed nose and sinus irrigation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Bridgeport Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 30, "start_date": "2010-05", "completion_date": "2011-03", "has_results": false, "last_update_posted_date": "2010-05-12", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 1, "location_summary": "Bridgeport, Connecticut", "locations": [ { "city": "Bridgeport", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT01121445" }, { "nct_id": "NCT03358329", "title": "Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Sinusitis", "Nasal Polyposis" ], "interventions": [ { "name": "S8 Sinus Implant", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Intersect ENT", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2017-11-13", "completion_date": "2019-01-17", "has_results": true, "last_update_posted_date": "2019-11-27", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 9, "location_summary": "Sacramento, California • New Haven, Connecticut • Naperville, Illinois + 6 more", "locations": [ { "city": "Sacramento", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Naperville", "state": "Illinois" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Covington", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03358329" }, { "nct_id": "NCT00639769", "title": "Irinotecan and Cisplatin in Treating Patients With Recurrent or Metastatic Head and Neck Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Head and Neck Cancer" ], "interventions": [ { "name": "cisplatin", "type": "DRUG" }, { "name": "irinotecan hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt-Ingram Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 41, "start_date": "2002-02", "completion_date": "2008-07", "has_results": true, "last_update_posted_date": "2012-09-14", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 8, "location_summary": "Macon, Georgia • Chattanooga, Tennessee • Jackson, Tennessee + 3 more", "locations": [ { "city": "Macon", "state": "Georgia" }, { "city": "Chattanooga", "state": "Tennessee" }, { "city": "Jackson", "state": "Tennessee" }, { "city": "Johnson City", "state": "Tennessee" }, { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00639769" }, { "nct_id": "NCT03390257", "title": "Study to Evaluate the Safety and Initial Effectiveness of the Sinusway™ for Endoscopy of Sinuses in Conjunction With BSD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Sinusitis" ], "interventions": [ { "name": "3NT flexible endoscope", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "3NT Medical Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2017-04-25", "completion_date": "2019-05-02", "has_results": true, "last_update_posted_date": "2020-12-08", "last_synced_at": "2026-10-15T02:58:09.896Z", "location_count": 2, "location_summary": "San Francisco, California • Salt Lake City, Utah", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT03390257" } ] }