{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Parenteral+Nutrition+Associated+Liver+Disease+PNALD",
    "query": {
      "condition": "Parenteral Nutrition Associated Liver Disease PNALD"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Parenteral+Nutrition+Associated+Liver+Disease+PNALD&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T18:05:24.933Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02476994",
      "title": "Pediatric Study to Evaluate Risk of Developing Essential Fatty Acid Deficiency When Receiving Clinolipid or Standard-of-Care Lipid Emulsion",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Essential Fatty Acid Deficiency (EFAD)"
      ],
      "interventions": [
        {
          "name": "Clinolipid",
          "type": "DRUG"
        },
        {
          "name": "Intralipid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baxter Healthcare Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 1,
      "start_date": "2015-05",
      "completion_date": "2016-10",
      "has_results": true,
      "last_update_posted_date": "2021-07-21",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 4,
      "location_summary": "Park Ridge, Illinois • Indianapolis, Indiana • Columbus, Ohio + 1 more",
      "locations": [
        {
          "city": "Park Ridge",
          "state": "Illinois"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02476994"
    },
    {
      "nct_id": "NCT02357576",
      "title": "Standard Lipid Therapy vs IVFE Minimization for Prevention of PNALD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cholestasis"
      ],
      "interventions": [
        {
          "name": "Intralipid 20% I.V. Fat Emulsion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 22,
      "start_date": "2016-05-21",
      "completion_date": "2019-11-08",
      "has_results": true,
      "last_update_posted_date": "2020-12-17",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 5,
      "location_summary": "Aurora, Colorado • Gainesville, Florida • Ann Arbor, Michigan + 2 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02357576"
    },
    {
      "nct_id": "NCT03072667",
      "title": "Omegaven for Compassionate Use in the Treatment of Parenteral Nutrition-Associated Liver Disease",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Cholestasis",
        "Liver Diseases"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Catherine Cibulskis, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2018-12-06",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03072667"
    },
    {
      "nct_id": "NCT01601652",
      "title": "Compassionate Use of an Intravenous Fish Oil Emulsion in Infants With Cholestasis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Parenteral Nutrition Associated Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Arthur J De Lorimier",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 12,
      "start_date": "2011-11",
      "completion_date": "2018-12",
      "has_results": true,
      "last_update_posted_date": "2021-01-27",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01601652"
    },
    {
      "nct_id": "NCT00910104",
      "title": "Cholestasis Reversal: Efficacy of IV Fish Oil",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Parenteral Nutrition Associated Liver Disease",
        "Short Bowel Syndrome",
        "Gastrointestinal Disease"
      ],
      "interventions": [
        {
          "name": "Omegaven®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mark Puder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 91,
      "start_date": "2006-08",
      "completion_date": "2019-01-23",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00910104"
    },
    {
      "nct_id": "NCT00826020",
      "title": "Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Parenteral Nutrition Associated Liver Disease PNALD",
        "Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven™",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2009-05-01",
      "completion_date": "2017-10-06",
      "has_results": true,
      "last_update_posted_date": "2023-10-05",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00826020"
    },
    {
      "nct_id": "NCT02929303",
      "title": "Expanded Access of Omegaven IV Fat Emulsion to Infants and Children With PNALD",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven IV lipid emulsion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 1,
      "location_summary": "Park Ridge, Illinois",
      "locations": [
        {
          "city": "Park Ridge",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02929303"
    },
    {
      "nct_id": "NCT06274788",
      "title": "Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parenteral Nutrition Associated Liver Disease (PNALD)",
        "Essential Fatty Acid Deficiency",
        "Malnutrition",
        "Pediatric ALL"
      ],
      "interventions": [
        {
          "name": "Omegaven® (fish oil triglycerides) Injectable Emulsion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Fresenius Kabi",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "1 Day to 17 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-12-15",
      "completion_date": "2027-03-01",
      "has_results": false,
      "last_update_posted_date": "2025-09-05",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 10,
      "location_summary": "Fountain Valley, California • Los Angeles, California • Chicago, Illinois + 7 more",
      "locations": [
        {
          "city": "Fountain Valley",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06274788"
    },
    {
      "nct_id": "NCT01323907",
      "title": "Compassionate Use of Omegaven IV Fat Emulsion",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven IV lipid emulsion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sivan Kinberg",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "2 Months to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": "2011-01",
      "completion_date": "2019-02-13",
      "has_results": false,
      "last_update_posted_date": "2020-02-06",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01323907"
    },
    {
      "nct_id": "NCT02121769",
      "title": "Omegaven Expanded Access Protocol",
      "overall_status": "NO_LONGER_AVAILABLE",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Parenteral Nutrition Associated Liver Disease"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Luke's Health System, Boise, Idaho",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2019-04-10",
      "last_synced_at": "2026-07-23T18:05:24.933Z",
      "location_count": 1,
      "location_summary": "Boise, Idaho",
      "locations": [
        {
          "city": "Boise",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02121769"
    }
  ]
}