{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Parotid+Tumor", "query": { "condition": "Parotid Tumor" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 18, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Parotid+Tumor&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-05-21T23:18:46.681Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05926765", "title": "A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands" ], "interventions": [ { "name": "AAV2-hAQP1 Concentration 1", "type": "GENETIC" }, { "name": "AAV2-hAQP1 Concentration 2", "type": "GENETIC" }, { "name": "Placebo", "type": "OTHER" }, { "name": "AAV2-hAQP1 Concentration 3", "type": "GENETIC" }, { "name": "AAV2-hAQP1 Concentration 4", "type": "GENETIC" } ], "intervention_types": [ "GENETIC", "OTHER" ], "sponsor": "MeiraGTx, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 276, "start_date": "2023-06-13", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-02-02", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 18, "location_summary": "Gilbert, Arizona • Duarte, California • Miami, Florida + 14 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Duarte", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05926765" }, { "nct_id": "NCT06054178", "title": "Identification of Nerves Using Fluorescein Sodium", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pleomorphic Adenoma of the Parotid", "Warthin Tumor", "Head and Neck Disorder", "Head and Neck", "Thyroid Disease", "Thyroidectomy" ], "interventions": [ { "name": "Fluorescein Sodium", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 8, "start_date": "2024-11-07", "completion_date": "2025-05-22", "has_results": true, "last_update_posted_date": "2026-05-20", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 1, "location_summary": "Palo Alto, California", "locations": [ { "city": "Palo Alto", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06054178" }, { "nct_id": "NCT04028479", "title": "The Registry of Oncology Outcomes Associated With Testing and Treatment", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Adenocarcinoma", "Adenocystic Carcinoma", "Anal Cancer", "Appendix Cancer", "Brain Tumor", "Glioblastoma", "Astrocytoma", "Bile Duct Cancer", "Cholangiocarcinoma", "Bladder Cancer", "Bone Cancer", "Synovial Sarcoma", "Chondrosarcoma", "Liposarcoma", "Sarcoma, Kaposi", "Sarcoma,Soft Tissue", "Sarcoma", "Osteosarcoma", "CNS Cancer", "Brain Stem Neoplasms", "Breast Cancer", "Cervical Cancer", "Colorectal Cancer", "Rectal Cancer", "Colon Cancer", "Esophageal Cancer", "Esophagus Cancer", "Cancer of Colon", "Pancreatic Cancer", "Cancer of Pancreas", "Testis Cancer", "Testicular Cancer", "Ureter Cancer", "Renal Cell Carcinoma", "Kidney Cancer", "Gestational Trophoblastic Tumor", "Head and Neck Neoplasms", "Parotid Tumor", "Larynx Cancer", "Tongue Cancer", "Pharynx Cancer", "Salivary Gland Cancer", "Acute Myeloid Leukemia", "Chronic Myeloid Leukemia", "Acute Lymphoblastic Leukemia", "Multiple Myeloma", "Non Hodgkin Lymphoma", "Carcinoid Tumor", "Lung Cancer", "Neuroendocrine Tumors", "Mesothelioma", "Thyroid Cancer", "Parathyroid Neoplasms", "Adrenal Cancer", "Small Bowel Cancer", "Stomach Cancer", "Liver Cancer", "Hepatic Cancer", "Melanoma", "Skin Cancer", "Unknown Primary Tumors", "Uterine Cancer", "Fallopian Tube Cancer", "Ovarian Cancer", "Prostate Cancer", "Vaginal Cancer", "Penile Cancer", "Vulvar Cancer", "Waldenstrom Macroglobulinemia", "Cancer, Advanced", "Thymus Cancer", "Nasopharyngeal Carcinoma", "Multiple Endocrine Neoplasia", "Pheochromocytoma", "Small Cell Carcinoma", "Pulmonary Carcinoma" ], "interventions": [ { "name": "Biomarker Testing (L)", "type": "DIAGNOSTIC_TEST" }, { "name": "Systemic Treatment (T)", "type": "DRUG" }, { "name": "Patient Reported Outcomes (P)", "type": "OTHER" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "DRUG", "OTHER" ], "sponsor": "Taproot Health", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 167, "start_date": "2021-05-05", "completion_date": "2024-10-31", "has_results": false, "last_update_posted_date": "2024-12-18", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 2, "location_summary": "Idaho Falls, Idaho • Laredo, Texas", "locations": [ { "city": "Idaho Falls", "state": "Idaho" }, { "city": "Laredo", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04028479" }, { "nct_id": "NCT04296266", "title": "Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Submandibular Gland Tumor", "Parotid Gland Tumor" ], "interventions": [ { "name": "Alda-341", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 10, "start_date": "2016-02", "completion_date": "2017-12-21", "has_results": false, "last_update_posted_date": "2020-03-05", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04296266" }, { "nct_id": "NCT06544798", "title": "Long-term Follow-up of Gene Therapy for Radiation-Induced Xerostomia", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands" ], "interventions": [ { "name": "AAV2-hAQP1", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "MeiraGTx, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 276, "start_date": "2024-08-02", "completion_date": "2032-02", "has_results": false, "last_update_posted_date": "2025-10-16", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 7, "location_summary": "Gilbert, Arizona • Miami, Florida • Iowa City, Iowa + 4 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Miami", "state": "Florida" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Columbia", "state": "Missouri" }, { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06544798" }, { "nct_id": "NCT00001523", "title": "Structure and Functional Status of Parotid Glands Exposed to Therapeutic Irradiation", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Radiation Injuries", "Xerostomia" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 20, "start_date": "1996-05", "completion_date": "2000-03", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00001523" }, { "nct_id": "NCT04420689", "title": "Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Parotid Neoplasm", "Thyroid Neoplasms", "Head and Neck Neoplasms", "Surgery", "Nerve Injury", "Imaging" ], "interventions": [ { "name": "Bevonescein", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alume Biosciences, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 27, "start_date": "2020-06-18", "completion_date": "2022-02-15", "has_results": true, "last_update_posted_date": "2025-05-08", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 3, "location_summary": "San Diego, California • Stanford, California • Boston, Massachusetts", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04420689" }, { "nct_id": "NCT04870762", "title": "Customized 3D Printed Oral Stents During Head and Neck Radiotherapy", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Head and Neck Carcinoma", "Malignant Parotid Gland Neoplasm", "Maxillary Sinus Carcinoma", "Nasal Cavity Carcinoma", "Oral Cavity Carcinoma", "Tongue Carcinoma", "Tonsillar Carcinoma" ], "interventions": [ { "name": "Best Practice", "type": "OTHER" }, { "name": "Medical Device Usage and Evaluation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 119, "start_date": "2021-05-26", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-04-15", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 7, "location_summary": "Phoenix, Arizona • Jacksonville, Florida • Indianapolis, Indiana + 2 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04870762" }, { "nct_id": "NCT02527226", "title": "Post-parotidectomy Facial Paresis: Intraoperative and Postoperative Factors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Parotid Neoplasms", "Facial Paralysis" ], "interventions": [ { "name": "Facial exercises", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 76, "start_date": "2015-08", "completion_date": "2016-07", "has_results": false, "last_update_posted_date": "2016-09-16", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 2, "location_summary": "Scottsdale, Arizona • Rochester, Minnesota", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02527226" }, { "nct_id": "NCT04043104", "title": "A Phase 1 Open-Label, Dose Escalation Study to Determine the Optimal Dose, Safety, and Activity of AAV2hAQP1 in Subjects With Radiation-Induced Parotid Gland Hypofunction and Xerostomia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Radiation-Induced Parotid Gland Hypofunction", "Xerostomia Due to Radiotherapy", "Head and Neck Cancer" ], "interventions": [ { "name": "AAV2hAQP1: 1 x 10^11 vg/gland (single gland)", "type": "DRUG" }, { "name": "AAV2hAQP1: 3 x 10^10 vg/gland (both glands)", "type": "DRUG" }, { "name": "AAV2hAQP1: 3 x 10^11 vg/gland (single gland)", "type": "DRUG" }, { "name": "AAV2hAQP1: 1 x 10^11 vg/gland (both glands)", "type": "DRUG" }, { "name": "AAV2hAQP1: 1 x 10^12 vg/gland (single gland)", "type": "DRUG" }, { "name": "AAV2hAQP1: 3 x 10^11 vg/gland (both glands)", "type": "DRUG" }, { "name": "AAV2hAQP1: 3 x 10^12 vg/gland (single gland)", "type": "DRUG" }, { "name": "AAV2hAQP1: 1 x 10^12 vg/gland (both glands)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MeiraGTx UK II Ltd", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 24, "start_date": "2019-06-30", "completion_date": "2023-03-28", "has_results": false, "last_update_posted_date": "2023-04-24", "last_synced_at": "2026-05-21T23:18:46.681Z", "location_count": 5, "location_summary": "Stanford, California • Louisville, Kentucky • Boston, Massachusetts + 2 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" }, { "city": "Charlotte", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04043104" } ] }