{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Patent+Ductus+Arteriosus",
    "query": {
      "condition": "Patent Ductus Arteriosus"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 44,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Patent+Ductus+Arteriosus&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:48:04.740Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01958320",
      "title": "Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Patent Ductus Arteriosus",
        "Surgery",
        "Necrotizing Enterocolitis",
        "Intestinal Perforation"
      ],
      "interventions": [
        {
          "name": "pharmacologic treatment of the PDA",
          "type": "OTHER"
        },
        {
          "name": "no pharmacologic treatment of the PDA",
          "type": "OTHER"
        },
        {
          "name": "NSAID",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Days",
        "maximum_age": "14 Days",
        "sex": "ALL",
        "summary": "5 Days to 14 Days"
      },
      "enrollment_count": 202,
      "start_date": "2013-12",
      "completion_date": "2017-06",
      "has_results": true,
      "last_update_posted_date": "2018-11-30",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 13,
      "location_summary": "San Diego, California • San Francisco, California • San Jose, California + 9 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Santa Clara",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01958320"
    },
    {
      "nct_id": "NCT00713700",
      "title": "AMPLATZER Duct Occluder II Clinical Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "AMPLATZER Duct Occluder II",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Months to 18 Years"
      },
      "enrollment_count": 192,
      "start_date": "2008-08",
      "completion_date": "2016-10-05",
      "has_results": true,
      "last_update_posted_date": "2019-02-04",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 25,
      "location_summary": "San Diego, California • San Francisco, California • Aurora, Colorado + 22 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00713700"
    },
    {
      "nct_id": "NCT02100683",
      "title": "Nit-Occlud PDA Post-Approval Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Patent Ductus Arteriosus (PDA)"
      ],
      "interventions": [
        {
          "name": "PDA Coil",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "PFM Medical, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "6 Months to 21 Years"
      },
      "enrollment_count": 184,
      "start_date": "2014-08",
      "completion_date": "2022-08-10",
      "has_results": false,
      "last_update_posted_date": "2022-10-04",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 11,
      "location_summary": "Loma Linda, California • Los Angeles, California • Madera, California + 8 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Madera",
          "state": "California"
        },
        {
          "city": "Oak Lawn",
          "state": "Illinois"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02100683"
    },
    {
      "nct_id": "NCT03456336",
      "title": "Management of the PDA Trial",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Premature",
        "Patent Ductus Arteriosus",
        "Infant, Newborn, Diseases",
        "Patent Ductus Arteriosus After Premature Birth"
      ],
      "interventions": [
        {
          "name": "Active Treatment",
          "type": "OTHER"
        },
        {
          "name": "Expectant Management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "48 Hours",
        "maximum_age": "21 Days",
        "sex": "ALL",
        "summary": "48 Hours to 21 Days"
      },
      "enrollment_count": 482,
      "start_date": "2019-02-22",
      "completion_date": "2027-05-30",
      "has_results": true,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 19,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • San Diego, California + 15 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03456336"
    },
    {
      "nct_id": "NCT06587282",
      "title": "PREEMIE: Study for Treatment of PDA in Premature Infants",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patent Ductus Arteriosus (PDA)"
      ],
      "interventions": [
        {
          "name": "Bloom Micro Occluder System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Merit Medical Systems, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Days",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Days and older"
      },
      "enrollment_count": 55,
      "start_date": "2025-03-06",
      "completion_date": "2029-03",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 9,
      "location_summary": "Sacramento, California • San Diego, California • Hollywood, Florida + 6 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06587282"
    },
    {
      "nct_id": "NCT00187447",
      "title": "Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "indomethacin (two different dosing regimens)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "48 Hours",
        "sex": "ALL",
        "summary": "Up to 48 Hours"
      },
      "enrollment_count": 100,
      "start_date": "2003-08",
      "completion_date": "2006-07",
      "has_results": false,
      "last_update_posted_date": "2008-06-04",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 3,
      "location_summary": "Davis, California • Chicago, Illinois • Providence, Rhode Island",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00187447"
    },
    {
      "nct_id": "NCT02620761",
      "title": "Fenoldopam to Prevent Renal Dysfunction in Indomethacin Treated Preterm Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Patent Ductus Arteriosus (PDA)",
        "Acute Kidney Injury (AKI)"
      ],
      "interventions": [
        {
          "name": "Fenoldopam",
          "type": "DRUG"
        },
        {
          "name": "0.9%NS",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "28 Days",
        "sex": "ALL",
        "summary": "0 Days to 28 Days"
      },
      "enrollment_count": 1,
      "start_date": "2019-02-06",
      "completion_date": "2020-01-31",
      "has_results": true,
      "last_update_posted_date": "2022-09-16",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02620761"
    },
    {
      "nct_id": "NCT01497054",
      "title": "Do Elevated BNP Levels Predict Hemodynamically Significant PDAs",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Albany Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 24 Hours"
      },
      "enrollment_count": 109,
      "start_date": "2011-12",
      "completion_date": "2013-04",
      "has_results": false,
      "last_update_posted_date": "2013-07-04",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01497054"
    },
    {
      "nct_id": "NCT04379843",
      "title": "The Efficacy of Implementing a Treatment Algorithm in Managing Patent Ductus Arteriosus (PDA) in the Extremely Low Birth Weight Neonatal Population.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PDA",
        "Low; Birthweight, Extremely (999 Grams or Less)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Pediatrix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 208,
      "start_date": "2016-07-27",
      "completion_date": "2021-07-31",
      "has_results": false,
      "last_update_posted_date": "2021-09-01",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 2,
      "location_summary": "Mesa, Arizona • Phoenix, Arizona",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04379843"
    },
    {
      "nct_id": "NCT00728117",
      "title": "Feeding During Ibuprofen or Indomethacin Treatment of Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "feeding",
          "type": "OTHER"
        },
        {
          "name": "fasting",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "33 Weeks",
        "sex": "ALL",
        "summary": "23 Weeks to 33 Weeks"
      },
      "enrollment_count": 177,
      "start_date": "2008-07",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2012-11-09",
      "last_synced_at": "2026-05-22T06:48:04.740Z",
      "location_count": 14,
      "location_summary": "San Francisco, California • San Jose, California • Chicago, Illinois + 11 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00728117"
    }
  ]
}