{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Patent+Ductus+Arteriosus+%28PDA%29",
    "query": {
      "condition": "Patent Ductus Arteriosus (PDA)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 44,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Patent+Ductus+Arteriosus+%28PDA%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T19:33:18.288Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00713700",
      "title": "AMPLATZER Duct Occluder II Clinical Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "AMPLATZER Duct Occluder II",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "6 Months to 18 Years"
      },
      "enrollment_count": 192,
      "start_date": "2008-08",
      "completion_date": "2016-10-05",
      "has_results": true,
      "last_update_posted_date": "2019-02-04",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 25,
      "location_summary": "San Diego, California • San Francisco, California • Aurora, Colorado + 22 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00713700"
    },
    {
      "nct_id": "NCT05880576",
      "title": "The Arch Watch Study: An Integrated Evaluation of Hemodynamics in Infants With Suspected Coarctation of the Aorta",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coarctation of the Aorta",
        "Aortic Arch Obstruction"
      ],
      "interventions": [
        {
          "name": "Monitoring using resonance Raman spectroscopy, pulse oximetry, blood pressure, and near-infrared spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "60 Days",
        "sex": "ALL",
        "summary": "0 Days to 60 Days"
      },
      "enrollment_count": 60,
      "start_date": "2023-10-01",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-08-20",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05880576"
    },
    {
      "nct_id": "NCT02750228",
      "title": "PDA Post NICU Discharge",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Pediatrix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Weeks",
        "maximum_age": "32 Weeks",
        "sex": "ALL",
        "summary": "22 Weeks to 32 Weeks"
      },
      "enrollment_count": 208,
      "start_date": "2016-05",
      "completion_date": "2020-06-30",
      "has_results": false,
      "last_update_posted_date": "2020-06-30",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 16,
      "location_summary": "Anchorage, Alaska • Phoenix, Arizona • Tucson, Arizona + 11 more",
      "locations": [
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Sunrise",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02750228"
    },
    {
      "nct_id": "NCT03026192",
      "title": "Near Infrared Spectroscopy to Determine Patent Ductus Arteriosus Closure",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "near infrared spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Albany Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "1 Week",
        "sex": "ALL",
        "summary": "1 Minute to 1 Week"
      },
      "enrollment_count": 4,
      "start_date": "2016-12",
      "completion_date": "2018-06-30",
      "has_results": false,
      "last_update_posted_date": "2019-01-23",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03026192"
    },
    {
      "nct_id": "NCT00961753",
      "title": "Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "optimized ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Standard Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "OSF Healthcare System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "29 Days",
        "sex": "ALL",
        "summary": "1 Day to 29 Days"
      },
      "enrollment_count": 10,
      "start_date": "2009-08",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2014-01-28",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 1,
      "location_summary": "Peoria, Illinois",
      "locations": [
        {
          "city": "Peoria",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00961753"
    },
    {
      "nct_id": "NCT03537144",
      "title": "Acetaminophen vs Indomethacin in Treating hsPDA",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "Indomethacin",
          "type": "DRUG"
        },
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Weeks",
        "maximum_age": "32 Weeks",
        "sex": "ALL",
        "summary": "22 Weeks to 32 Weeks"
      },
      "enrollment_count": 37,
      "start_date": "2016-06",
      "completion_date": "2018-09",
      "has_results": false,
      "last_update_posted_date": "2019-12-03",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 3,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03537144"
    },
    {
      "nct_id": "NCT07114718",
      "title": "Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Heart Disease",
        "Congenital Heart Disease (CHD)"
      ],
      "interventions": [
        {
          "name": "Ductus Arteriosus Stent",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Starlight Cardiovascular Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "1 Minute to 6 Months"
      },
      "enrollment_count": 35,
      "start_date": "2026-01-16",
      "completion_date": "2028-04",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Stanford, California • Aurora, Colorado + 5 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07114718"
    },
    {
      "nct_id": "NCT01628133",
      "title": "Packed Red Blood Cell Transfusion and Intestinal Blood Flow in Preterm Neonates",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intestinal Blood Flow"
      ],
      "interventions": [
        {
          "name": "ultrasound",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "3 Months",
        "sex": "ALL",
        "summary": "Up to 3 Months"
      },
      "enrollment_count": 25,
      "start_date": "2011-12",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2014-06-20",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01628133"
    },
    {
      "nct_id": "NCT01758913",
      "title": "Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Taipei Medical University Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 110,
      "start_date": "2007-02",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2013-01-03",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01758913"
    },
    {
      "nct_id": "NCT01028183",
      "title": "Impact of Maternal-infant Therapeutics on Safety, Mortality, and Disability",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gastroesophageal Reflux",
        "Presumed Sepsis",
        "Patent Ductus Arteriosus",
        "Chronic Lung Disease",
        "Neurodevelopmental Impairment"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "5 Days",
        "sex": "ALL",
        "summary": "Up to 5 Days"
      },
      "enrollment_count": 0,
      "start_date": "2010-08",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2013-01-16",
      "last_synced_at": "2026-06-10T19:33:18.288Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01028183"
    }
  ]
}