{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Patent+Ductus+Arteriosus+in+Premature+Infants",
    "query": {
      "condition": "Patent Ductus Arteriosus in Premature Infants"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 21,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Patent+Ductus+Arteriosus+in+Premature+Infants&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T10:16:34.128Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06587282",
      "title": "PREEMIE: Study for Treatment of PDA in Premature Infants",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patent Ductus Arteriosus (PDA)"
      ],
      "interventions": [
        {
          "name": "Bloom Micro Occluder System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Merit Medical Systems, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Days",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Days and older"
      },
      "enrollment_count": 55,
      "start_date": "2025-03-06",
      "completion_date": "2029-03",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 9,
      "location_summary": "Sacramento, California • San Diego, California • Hollywood, Florida + 6 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06587282"
    },
    {
      "nct_id": "NCT03551600",
      "title": "Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infant, Premature",
        "Congenital Heart Disease",
        "Patent Ductus Arteriosus",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Near-infrared spectroscopy (NIRS)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Days",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "12 Days to 6 Months"
      },
      "enrollment_count": 64,
      "start_date": "2015-10",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2023-04-04",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 3,
      "location_summary": "Murray, Utah • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03551600"
    },
    {
      "nct_id": "NCT00767039",
      "title": "Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Prematurity",
        "Respiratory Distress Syndrome",
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "Survanta (beractant)",
          "type": "DRUG"
        },
        {
          "name": "Curosurf (poractant)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alan Fujii",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Hours",
        "sex": "ALL",
        "summary": "Up to 8 Hours"
      },
      "enrollment_count": 52,
      "start_date": "2005-01",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2011-10-03",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00767039"
    },
    {
      "nct_id": "NCT01628133",
      "title": "Packed Red Blood Cell Transfusion and Intestinal Blood Flow in Preterm Neonates",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intestinal Blood Flow"
      ],
      "interventions": [
        {
          "name": "ultrasound",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "3 Months",
        "sex": "ALL",
        "summary": "Up to 3 Months"
      },
      "enrollment_count": 25,
      "start_date": "2011-12",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2014-06-20",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01628133"
    },
    {
      "nct_id": "NCT03008876",
      "title": "IV Acetaminophen and Patent Ductus Arteriosus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "Acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Albany Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "2 Weeks",
        "sex": "ALL",
        "summary": "1 Minute to 2 Weeks"
      },
      "enrollment_count": 10,
      "start_date": "2017-01-01",
      "completion_date": "2019-06-30",
      "has_results": false,
      "last_update_posted_date": "2019-07-08",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03008876"
    },
    {
      "nct_id": "NCT05011149",
      "title": "Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCT",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Patent Ductus Arteriosus After Premature Birth"
      ],
      "interventions": [
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "IWK Health Centre",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "Up to 72 Hours"
      },
      "enrollment_count": 100,
      "start_date": "2022-01-10",
      "completion_date": "2024-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-06-21",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 3,
      "location_summary": "Orange, California • San Diego, California • Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05011149"
    },
    {
      "nct_id": "NCT02750228",
      "title": "PDA Post NICU Discharge",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Pediatrix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Weeks",
        "maximum_age": "32 Weeks",
        "sex": "ALL",
        "summary": "22 Weeks to 32 Weeks"
      },
      "enrollment_count": 208,
      "start_date": "2016-05",
      "completion_date": "2020-06-30",
      "has_results": false,
      "last_update_posted_date": "2020-06-30",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 16,
      "location_summary": "Anchorage, Alaska • Phoenix, Arizona • Tucson, Arizona + 11 more",
      "locations": [
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Sunrise",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02750228"
    },
    {
      "nct_id": "NCT03026192",
      "title": "Near Infrared Spectroscopy to Determine Patent Ductus Arteriosus Closure",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "near infrared spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Albany Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "1 Week",
        "sex": "ALL",
        "summary": "1 Minute to 1 Week"
      },
      "enrollment_count": 4,
      "start_date": "2016-12",
      "completion_date": "2018-06-30",
      "has_results": false,
      "last_update_posted_date": "2019-01-23",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03026192"
    },
    {
      "nct_id": "NCT03701074",
      "title": "Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus Arteriosus",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Patent Ductus Arteriosus",
        "Preterm Infant",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Ibuprofen and acetaminophen",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen and placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of South Alabama",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Days",
        "maximum_age": "21 Days",
        "sex": "ALL",
        "summary": "5 Days to 21 Days"
      },
      "enrollment_count": 1,
      "start_date": "2018-12-15",
      "completion_date": "2020-12-02",
      "has_results": true,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 1,
      "location_summary": "Mobile, Alabama",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03701074"
    },
    {
      "nct_id": "NCT03277768",
      "title": "Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Premature Infant",
        "Patent Ductus Arteriosus",
        "Hemodynamic Instability"
      ],
      "interventions": [
        {
          "name": "Resonance Raman Spectroscopy (RRS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 55,
      "start_date": "2015-05-01",
      "completion_date": "2018-08-23",
      "has_results": false,
      "last_update_posted_date": "2019-09-10",
      "last_synced_at": "2026-07-23T10:16:34.128Z",
      "location_count": 2,
      "location_summary": "Gainesville, Florida • Boston, Massachusetts",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03277768"
    }
  ]
}