{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pathophysiology&page=105",
    "query": {
      "condition": "Pathophysiology",
      "page": 105
    },
    "page_size": 10
  },
  "pagination": {
    "page": 105,
    "page_size": 10,
    "total_count": 3983,
    "total_pages": 399,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pathophysiology&page=106&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pathophysiology&page=104&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-10T15:50:43.067Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00394173",
      "title": "Efficacy, Safety and Tolerability of DNK333 (25 mg Bid) in Women With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Irritable Bowel Syndrome With Diarrhea (IBS-D)"
      ],
      "interventions": [
        {
          "name": "DNK333",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 180,
      "start_date": "2006-09",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2017-02-27",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 37,
      "location_summary": "Tucson, Arizona • North Little Rock, Arkansas • Los Angeles, California + 34 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "North Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Riverside",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00394173"
    },
    {
      "nct_id": "NCT04901494",
      "title": "SSRI's and the Rate of Progression From MCI to Dementia",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mild Cognitive Impairment",
        "Dementia",
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "SSRI",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2021-09-01",
      "completion_date": "2023-10-06",
      "has_results": false,
      "last_update_posted_date": "2023-10-11",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04901494"
    },
    {
      "nct_id": "NCT05380180",
      "title": "Enhancing Quality of Life for Older Adults With and Without Mild Cognitive Impairment (MCI) Through Social Engagement Over Video Technology",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Mild Cognitive Impairment",
        "Aging Well"
      ],
      "interventions": [
        {
          "name": "OneClick Social Engagement Intervention",
          "type": "OTHER"
        },
        {
          "name": "OneClick Social Engagement Intervention Extension",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 99,
      "start_date": "2022-04-15",
      "completion_date": "2023-06-06",
      "has_results": true,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 2,
      "location_summary": "Champaign, Illinois • Chicago, Illinois",
      "locations": [
        {
          "city": "Champaign",
          "state": "Illinois"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05380180"
    },
    {
      "nct_id": "NCT06027554",
      "title": "The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Frailty",
        "Mild Cognitive Impairment",
        "Aging"
      ],
      "interventions": [
        {
          "name": "Mitoquinone Mesylate",
          "type": "DRUG"
        },
        {
          "name": "Placebo capsule",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "65 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2024-10-07",
      "completion_date": "2028-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-12",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06027554"
    },
    {
      "nct_id": "NCT04466722",
      "title": "The A-LIST WMM Insights Series",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Dementia",
        "Mild Cognitive Impairment"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "UsAgainstAlzheimer's",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 10000,
      "start_date": "2018-08-15",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-06-15",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04466722"
    },
    {
      "nct_id": "NCT03098459",
      "title": "Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Delirium",
        "Cognitive Impairment",
        "Alzheimer; Early Onset",
        "Trauma",
        "Polytrauma",
        "Traumatic Brain Injury",
        "ICU",
        "Critical Illness"
      ],
      "interventions": [
        {
          "name": "Non-interventional observational prospective cohort study",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 432,
      "start_date": "2017-11-02",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2026-01-13",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03098459"
    },
    {
      "nct_id": "NCT06105242",
      "title": "Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "CTEPH"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Intermountain Health Care, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2022-05-30",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-10-27",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 1,
      "location_summary": "Murray, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06105242"
    },
    {
      "nct_id": "NCT03968731",
      "title": "Meibomian Gland Dysfunction Management With ZEST Protocol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meibomian Gland Dysfunction",
        "Dry Eye Syndromes",
        "Ocular Surface Disease"
      ],
      "interventions": [
        {
          "name": "Zocular Eyelid System Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of the Incarnate Word",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2019-06-10",
      "completion_date": "2020-05-31",
      "has_results": false,
      "last_update_posted_date": "2022-07-14",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03968731"
    },
    {
      "nct_id": "NCT00903695",
      "title": "MemoryXL Effects on Mild Cognitive Impairment Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Memory XL",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "55 Years to 85 Years"
      },
      "enrollment_count": 10,
      "start_date": "2009-06",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2012-01-26",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 2,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00903695"
    },
    {
      "nct_id": "NCT06999265",
      "title": "Effect of Peripheral Neuromodulation on Vaginal Blood Flow - Study 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Female Sexual Dysfunction",
        "Female Sexual Dysfunction Due to Physical Condition"
      ],
      "interventions": [
        {
          "name": "Transcutaneous electrical nerve stimulation - Tibial Nerve",
          "type": "DEVICE"
        },
        {
          "name": "Transcutaneous electrical nerve stimulation - Genital Nerve",
          "type": "DEVICE"
        },
        {
          "name": "Neutral and Erotic Film Clip Alternation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 15,
      "start_date": "2022-09-14",
      "completion_date": "2024-06-05",
      "has_results": true,
      "last_update_posted_date": "2025-07-16",
      "last_synced_at": "2026-11-10T15:50:43.067Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06999265"
    }
  ]
}